Publications by authors named "Wouter van Winden"

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Single Cell Protein Production From Ethanol: Model-Based Bioreactor Operation at Industrial Scale.
Eduardo Almeida Benalcázar, Wouter A van Winden, Lars Puiman, John A Posada, Mickel L A Jansen

Biotechnol Bioeng· June 2025

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Enzyme-constrained metabolic model and metabolic engineering of for the development of sustainable production processes.
Antonio Caivano, Wouter van Winden, Giuliano Dragone, Solange I Mussatto

Comput Struct Biotechnol J· September 2023

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Towards closed carbon loop fermentations: Cofeeding of Yarrowia lipolytica with glucose and formic acid.
Wouter A van Winden, Robert Mans, Stefaan Breestraat, Rob A J Verlinden, Álvaro Mielgo-Gómez

Biotechnol Bioeng· August 2022

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A 9-pool metabolic structured kinetic model describing days to seconds dynamics of growth and product formation by Penicillium chrysogenum.
Wenjun Tang, Amit T Deshmukh, Cees Haringa, Guan Wang, Walter van Gulik, Wouter van Winden

Biotechnol Bioeng· August 2017

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Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes.
Jurgen R Haanstra, Arjen van Tuijl, Jan van Dam, Wouter van Winden, Aloysius G M Tielens

Int J Parasitol· June 2012

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Identification of informative metabolic responses using a minibioreactor: a small step change in the glucose supply rate creates a large metabolic response in Saccharomyces cerevisiae.
Fredrick O Aboka, Wouter A van Winden, Mashego M Reginald, Walter M van Gulik, Marco van de Berg

Yeast· March 2012

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Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol.
Zheng Zhao, Karel Kuijvenhoven, Walter M van Gulik, Joseph J Heijnen, Wouter A van Winden

Appl Microbiol Biotechnol· January 2011

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Fast dynamic response of the fermentative metabolism of Escherichia coli to aerobic and anaerobic glucose pulses.
Alvaro R Lara, Hilal Taymaz-Nikerel, Mlawule R Mashego, Walter M van Gulik, Joseph J Heijnen, Wouter A van Winden

Biotechnol Bioeng· December 2009

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Simultaneous quantification of free nucleotides in complex biological samples using ion pair reversed phase liquid chromatography isotope dilution tandem mass spectrometry.
Reza M Seifar, Cor Ras, Jan C van Dam, Walter M van Gulik, Joseph J Heijnen, Wouter A van Winden

Anal Biochem· May 2009

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Dynamic 13C-tracer study of storage carbohydrate pools in aerobic glucose-limited Saccharomyces cerevisiae confirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate.
Fredrick O Aboka, Joseph J Heijnen, Wouter A van Winden

FEMS Yeast Res· March 2009

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Model reduction and a priori kinetic parameter identifiability analysis using metabolome time series for metabolic reaction networks with linlog kinetics.
I Emrah Nikerel, Wouter A van Winden, Peter J T Verheijen, Joseph J Heijnen

Metab Eng· January 2009

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Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum.
Zheng Zhao, Karel Kuijvenhoven, Cor Ras, Walter M van Gulik, Joseph J Heijnen, Wouter A van Winden

Metab Eng· July 2008

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Malic acid production by Saccharomyces cerevisiae: engineering of pyruvate carboxylation, oxaloacetate reduction, and malate export.
Rintze M Zelle, Erik de Hulster, Wouter A van Winden, Pieter de Waard, Cor Dijkema

Appl Environ Microbiol· May 2008

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Quantitative analysis of metabolites in complex biological samples using ion-pair reversed-phase liquid chromatography-isotope dilution tandem mass spectrometry.
Reza M Seifar, Zheng Zhao, Jan van Dam, Wouter van Winden, Walter van Gulik

J Chromatogr A· April 2008

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13C-Labeled metabolic flux analysis of a fed-batch culture of elutriated Saccharomyces cerevisiae.
Roeland Costenoble, Dirk Müller, Timo Barl, Walter M van Gulik, Wouter A van Winden

FEMS Yeast Res· June 2007

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Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived C-labelling data.
Roelco J Kleijn, Jan-Maarten A Geertman, Beckley K Nfor, Cor Ras, Dick Schipper, Wouter A van Winden

FEMS Yeast Res· March 2007

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Cytosolic NADPH metabolism in penicillin-G producing and non-producing chemostat cultures of Penicillium chrysogenum.
Roelco J Kleijn, Feng Liu, Wouter A van Winden, Walter M van Gulik, Cor Ras

Metab Eng· January 2007

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Characterization of an experimental miniature bioreactor for cellular perturbation studies.
Fredrick O Aboka, Huiling Yang, Lodewijk P de Jonge, Rob Kerste, Wouter A van Winden

Biotechnol Bioeng· December 2006

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A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics.
I Emrah Nikerel, Wouter A van Winden, Walter M van Gulik, Joseph J Heijnen

BMC Bioinformatics· December 2006

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13C-labeled gluconate tracing as a direct and accurate method for determining the pentose phosphate pathway split ratio in Penicillium chrysogenum.
Roelco J Kleijn, Wouter A van Winden, Cor Ras, Walter M van Gulik, Dick Schipper

Appl Environ Microbiol· July 2006

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Short-term metabolome dynamics and carbon, electron, and ATP balances in chemostat-grown Saccharomyces cerevisiae CEN.PK 113-7D following a glucose pulse.
Liang Wu, Jan van Dam, Dick Schipper, M T A Penia Kresnowati, Angela M Proell, Wouter A van Winden

Appl Environ Microbiol· May 2006

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In vivo kinetics of primary metabolism in Saccharomyces cerevisiae studied through prolonged chemostat cultivation.
Liang Wu, Mlawule R Mashego, Angela M Proell, Jacobus L Vinke, Cor Ras, Wouter A van Winden

Metab Eng· March 2006

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Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence.
Roelco J Kleijn, Wouter A van Winden, Walter M van Gulik, Joseph J Heijnen

FEBS J· October 2005

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Application of metabolome data in functional genomics: a conceptual strategy.
Liang Wu, Wouter A van Winden, Walter M van Gulik, Joseph J Heijnen

Metab Eng· July 2005

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Determination of elasticities, concentration and flux control coefficients from transient metabolite data using linlog kinetics.
M T A Penia Kresnowati, Wouter A van Winden, Joseph J Heijnen

Metab Eng· March 2005

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