Publications by authors named "Xavier Meckler"

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Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments.
Xavier Meckler, Frédéric Checler

J Biol Chem· June 2016

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Visualization of specific γ-secretase complexes using bimolecular fluorescence complementation.
Xavier Meckler, Frédéric Checler

J Alzheimers Dis· October 2014

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A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production.
Virginie Buggia-Prévot, Celia G Fernandez, Vinod Udayar, Kulandaivelu S Vetrivel, Aureliane Elie, Xavier Meckler

Cell Rep· December 2013

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Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of gamma-secretase activity toward amyloid precursor protein and other substrates.
Ping Gong, Kulandaivelu S Vetrivel, Phuong D Nguyen, Xavier Meckler, Haipeng Cheng

J Biol Chem· December 2010

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Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin.
Xavier Meckler, Jelita Roseman, Pritam Das, Haipeng Cheng, Susan Pei

J Neurosci· December 2010

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Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts.
Kulandaivelu S Vetrivel, Xavier Meckler, Ying Chen, Phuong D Nguyen, Nabil G Seidah

J Biol Chem· February 2009

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S-palmitoylation of gamma-secretase subunits nicastrin and APH-1.
Haipeng Cheng, Kulandaivelu S Vetrivel, Renaldo C Drisdel, Xavier Meckler, Ping Gong

J Biol Chem· January 2009

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Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
Kulandaivelu S Vetrivel, Xulun Zhang, Xavier Meckler, Haipeng Cheng, Sungho Lee

J Biol Chem· July 2008

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Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts.
Haipeng Cheng, Kulandaivelu S Vetrivel, Ping Gong, Xavier Meckler, Angèle Parent

Nat Clin Pract Neurol· July 2007

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