Publications by authors named "Xavier Thuru"

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HR-MS Analysis of the Covalent Binding of Edaravone to 5-Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5-Formylcytidine Residue.
Romain Regnault, Mostafa Kouach, Laurence Goossens, Xavier Thuru, Christian Bailly

Rapid Commun Mass Spectrom· July 2025

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Activity of pyridyl-pyrazolone derivatives against Trypanosoma cruzi.
Denise da Gama Jaen Batista, Ludmila Ferreira de Almeida Fiuza, Frédérique Klupsch, Krislayne Nunes da Costa, Marcos Meuser Batista, Xavier Thuru

Exp Parasitol· July 2024

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MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma.
Lama Hasan Bou Issa, Léa Fléchon, William Laine, Aicha Ouelkdite, Silvia Gaggero, Xavier Thuru

iScience· April 2024

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Targeting of Tetraspanin CD81 with Monoclonal Antibodies and Small Molecules to Combat Cancers and Viral Diseases.
Christian Bailly, Xavier Thuru

Cancers (Basel)· April 2023

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Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties.
Romain Regnault, Frédérique Klupsch, Hassiba El-Bouazzati, Romain Magnez, Raphaël Le Biannic, Xavier Thuru

Molecules· April 2023

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Soluble TIM-3 as a biomarker of progression and therapeutic response in cancers and other of human diseases.
Christian Bailly, Xavier Thuru, Laurence Goossens, Jean-François Goossens

Biochem Pharmacol· March 2023

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A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition.
Xavier Thuru, Romain Magnez, Gérard Vergoten, Christian Bailly

Biomed Hub· January 2023

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IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.
Silvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, Paul K Fyfe, Malo Leprohon, Xavier Thuru

Sci Immunol· December 2022

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Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease.
Ilda Coku, Eugénie Mutez, Sabiha Eddarkaoui, Sébastien Carrier, Antoine Marchand, Xavier Thuru

Mov Disord· August 2022

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Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors.
Xavier Thuru, Romain Magnez, Hassiba El-Bouazzati, Gérard Vergoten, Bruno Quesnel

Cancers (Basel)· July 2022

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Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases.
Romain Magnez, Christian Bailly, Xavier Thuru

Int J Mol Sci· July 2022

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Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction.
Raphaël Le Biannic, Romain Magnez, Frédérique Klupsch, Natascha Leleu-Chavain, Bryan Thiroux, Xavier Thuru

Eur J Med Chem· June 2022

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Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents.
Natascha Leleu-Chavain, Romain Regnault, Hania Ahouari, Raphaël Le Biannic, Mostafa Kouach, Xavier Thuru

Molecules· May 2022

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p65/RelA NF-κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics.
Yasmine Touil, Céline Latreche-Carton, Hassiba El Bouazzati, Anne-Lucie Nugues, Nathalie Jouy, Xavier Thuru

J Cell Biochem· March 2022

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A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.
Antoine Marchand, Alessia Sarchione, Panagiotis S Athanasopoulos, Hélène Bauderlique-Le Roy, Liesel Goveas, Xavier Thuru

Cells· March 2022

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Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells.
Sarah Trouvilliez, Julien Cicero, Romain Lévêque, Léo Aubert, Cyril Corbet, Xavier Thuru

J Exp Clin Cancer Res· March 2022

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Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.
Manon Sturbaut, Fabrice Bailly, Mathilde Coevoet, Pasquale Sileo, Martine Pugniere, Xavier Thuru

Eur J Med Chem· December 2021

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Modulation of the Gal-9/TIM-3 Immune Checkpoint with α-Lactose. Does Anomery of Lactose Matter?
Christian Bailly, Xavier Thuru, Bruno Quesnel

Cancers (Basel)· December 2021

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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis.
Nicolas Stoup, Maxime Liberelle, Céline Schulz, Sumeyye Cavdarli, Romain Vasseur, Xavier Thuru

Cancers (Basel)· November 2021

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Tau Stabilizes Chromatin Compaction.
Thomas Rico, Melissa Gilles, Alban Chauderlier, Thomas Comptdaer, Romain Magnez, Xavier Thuru

Front Cell Dev Biol· October 2021

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Properties and reactivity of the folic acid and folate photoproduct 6-formylpterin.
Jean-François Goossens, Xavier Thuru, Christian Bailly

Free Radic Biol Med· August 2021

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Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases.
Christian Bailly, Xavier Thuru, Bruno Quesnel

Cancers (Basel)· June 2021

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Aggressiveness Potential of Spontaneous Canine Mucosal Melanoma Can Dictate Distinct Cancer Stem Cell Compartment Behaviors in Regard to Their Initial Size and Expansion Abilities.
Yasmine Touil, Zacharie Segaoula, Xavier Thuru, Sylvie Galiègue-Zouitina, Dominique Tierny

Stem Cells Dev· July 2020

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Publisher Correction: MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis.
Maxime Liberelle, Romain Magnez, Xavier Thuru, Yamina Bencheikh, Severine Ravez

Sci Rep· April 2020

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Measurement of Protein-Protein Interactions through Microscale Thermophoresis (MST).
Magnez Romain, Bryan Thiroux, Morgane Tardy, Bruno Quesnel, Xavier Thuru

Bio Protoc· April 2020

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