Publications by authors named "Xiangzheng Fu"

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ViruSeg: Harnessing the Power of Large Language-Image Model for Enhanced Virus Image Segmentation.
Shengxiang Wang, Xiangzheng Fu, Zhenya Du, Xinxin Liu, Qiaochu Mai

Interdiscip Sci· December 2025

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MicroEnvPPI: Microenvironment-Aware Optimization Enables Generalizable Protein-Protein Interaction Prediction.
Kun Yang, Yifan Chen, Yanshi Wei, Mingrong Xiang, Linlin Zhuo, Xiangzheng Fu

J Chem Inf Model· November 2025

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MOFormer: navigating the antimicrobial peptide design space with Pareto-based multi-objective transformer.
Li Wang, Xiangzheng Fu, Jiahao Yang, Xinyi Zhang, Xiucai Ye

Brief Bioinform· November 2025

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ST-GCP: a graph convolutional network model with contrastive consistency and permutation for spatial transcriptomics.
Yajie Meng, Yongkang Wang, Cheng Guo, Xianfang Tang, Zilong Zhang, Xiangzheng Fu

Brief Bioinform· November 2025

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PKAN: Leveraging Kolmogorov-Arnold Networks and Multi-Modal Learning for Peptide Prediction With Advanced Language Models.
Li Wang, Xiangzheng Fu, Xiucai Ye, Tetsuya Sakurai, Xiangxiang Zeng

IEEE J Biomed Health Inform· October 2025

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An image-based protein-ligand binding representation learning framework via multi-level flexible dynamics trajectory pre-training.
Hongxin Xiang, Mingquan Liu, Linlin Hou, Shuting Jin, Jianmin Wang, Xiangzheng Fu

Bioinformatics· October 2025

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A Innovative Strategy for Identifying Subtypes Through the Analysis of Multi-Omics Data with Adversarial Autoencoders.
Xia Chen, Hao Nie, Quanwei Chen, Xiang Zhang, Zixing He, Xiangzheng Fu

J Comput Biol· September 2025

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Uncertainty-Aware Deep Learning and Structural Feature Analysis for Reliable Nephrotoxicity Prediction.
Jian-Wang Liu, Ke-Yi Liu, You-Chao Deng, Shao-Hua Shi, Xiang-Zheng Fu

J Chem Inf Model· September 2025

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Decoding the limits of deep learning in molecular docking for drug discovery.
Yue Li, Jiacai Yi, Hui Li, Kun Li, Fenghua Kang, Xiangzheng Fu

Chem Sci· September 2025

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Multi-scale information fusion and decoupled representation learning for robust microbe-disease interaction prediction.
Wentao Wang, Qiaoying Yan, Qingquan Liao, Xinyuan Jin, Yinyin Gong, Xiangzheng Fu

J Pharm Anal· August 2025

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GRAPE: graph-regularized protein language modeling unlocks TCR-epitope binding specificity.
Xiangzheng Fu, Li Peng, Haowen Chen, Mingqiang Rong, Yifan Chen

Brief Bioinform· August 2025

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GH-UNet: group-wise hybrid convolution-VIT for robust medical image segmentation.
Shengxiang Wang, Ge Li, Min Gao, Linlin Zhuo, Mingzhe Liu, Xiangzheng Fu

NPJ Digit Med· July 2025

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PhytoCluster: a generative deep learning model for clustering plant single-cell RNA-seq data.
Hao Wang, Xiangzheng Fu, Lijia Liu, Yi Wang, Jingpeng Hong

aBIOTECH· June 2025

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DrugKANs: A Paradigm to Enhance Drug-Target Interaction Prediction With KANs.
Xiangzheng Fu, Zhenya Du, Yifan Chen, Haiting Chen, Linlin Zhuo

IEEE J Biomed Health Inform· May 2025

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Leveraging explainable multi-scale features for fine-grained circRNA-miRNA interaction prediction.
Li Peng, Wang Wang, Zongyi Yang, Xiangzheng Fu, Wei Liang

BMC Biol· May 2025

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MultiCTox: Empowering Accurate Cardiotoxicity Prediction through Adaptive Multimodal Learning.
Lin Feng, Xiangzheng Fu, Zhenya Du, Yuting Guo, Linlin Zhuo

J Chem Inf Model· April 2025

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HMAMP: Designing Highly Potent Antimicrobial Peptides Using a Hypervolume-Driven Multiobjective Deep Generative Model.
Li Wang, Yiping Liu, Xiangzheng Fu, Xiucai Ye, Junfeng Shi

J Med Chem· April 2025

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CardiOT: Towards Interpretable Drug Cardiotoxicity Prediction Using Optimal Transport and Kolmogorov--Arnold Networks.
Xinyu Zhang, Hao Wang, Zhenya Du, Linlin Zhuo, Xiangzheng Fu

IEEE J Biomed Health Inform· March 2025

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AnomalGRN: deciphering single-cell gene regulation network with graph anomaly detection.
Zhecheng Zhou, Jinhang Wei, Mingzhe Liu, Linlin Zhuo, Xiangzheng Fu

BMC Biol· March 2025

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metaCDA: A Novel Framework for CircRNA-Driven Drug Discovery Utilizing Adaptive Aggregation and Meta-Knowledge Learning.
Li Peng, Huaping Li, Sisi Yuan, Tao Meng, Yifan Chen, Xiangzheng Fu

J Chem Inf Model· February 2025

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Deep learning-based cell-specific gene regulatory networks inferred from single-cell multiome data.
Junlin Xu, Changcheng Lu, Shuting Jin, Yajie Meng, Xiangzheng Fu

Nucleic Acids Res· February 2025

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AtML: An Arabidopsis thaliana root cell identity recognition tool for medicinal ingredient accumulation.
Shicong Yu, Lijia Liu, Hao Wang, Shen Yan, Shuqin Zheng, Xiangzheng Fu

Methods· November 2024

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BloodPatrol: Revolutionizing Blood Cancer Diagnosis - Advanced Real-Time Detection Leveraging Deep Learning & Cloud Technologies.
Jinhang Wei, Longyue Wang, Zhecheng Zhou, Linlin Zhuo, Xiangxiang Zeng, Xiangzheng Fu

IEEE J Biomed Health Inform· November 2024

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ET-PROTACs: modeling ternary complex interactions using cross-modal learning and ternary attention for accurate PROTAC-induced degradation prediction.
Lijun Cai, Guanyu Yue, Yifan Chen, Li Wang, Xiaojun Yao, Xiangzheng Fu

Brief Bioinform· November 2024

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DrugReAlign: a multisource prompt framework for drug repurposing based on large language models.
Jinhang Wei, Linlin Zhuo, Xiangzheng Fu, XiangXiang Zeng, Li Wang

BMC Biol· October 2024

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