Publications by authors named "Xianjun Qu"

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Inhibition of sphingosine-1-phosphate receptor-2 attenuates chronic gastritis via blocking nuclear translocation of S1P receptors in epithelial cells.
Ke-Qin Li, Zhi-Meng Sun, Han-Bing Shao, Ming-Yong Tan, Ming Yang, Xian-Jun Qu

Br J Pharmacol· December 2025

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Activation of sphingosine-1-phosphate receptor 2 (S1PR2) upregulates dihydropyrimidine dehydrogenase (DPD) expression in colon cancer cells.
Zhi-Kun Guo, Xin-Feng Wu, Ming-Yong Tan, Wei-Shi Liang, Yu-Meng Yang, Xian-Jun Qu

J Adv Res· November 2025

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Comparison of Hybrid Surgery and Two-Level ACDF in Treating Consecutive Cervical Degenerative Disc Disease: A Systematic Review and Meta-Analysis.
Yihan Yang, Weishi Liang, Duan Sun, Bo Han, Zhangfu Li, Xianjun Qu

Global Spine J· November 2025

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Rutin Attenuates Distraction Spinal Cord Injury by Inhibiting Microglial Inflammation Through Downregulation of P38 MAPK/NF-κB/STAT3 Pathway.
Junrui Jonathan Hai, Weishi Liang, Duan Sun, Peng Yin, Bo Han, Xianjun Qu

Mol Neurobiol· May 2025

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Conjugated bile acids promote metabolic dysfunction-associated steatotic liver disease through inducing nuclear translocation of sphingosine-1-phosphate receptor 2 to disrupt peroxisome proliferator-activated receptor alpha.
Rong-Rong Miao, Ming-Yong Tan, Han-Bing Shao, Zhi-Meng Sun, Sheng Zhan, Xian-Jun Qu

Cell Commun Signal· May 2025

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Inhibition of sphingosine-1-phosphate receptor-2 attenuates idiopathic pulmonary fibrosis by preventing its binding to dapper1 in bronchial epithelial cells.
Si-Yuan Mu, Rui Xu, Xin-Feng Wu, Yu-Yao Cheng, Zhi-Meng Sun, Xian-Jun Qu

Br J Pharmacol· April 2025

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PRDX1 inhibits ferroptosis by binding to Cullin-3 as a molecular chaperone in colorectal cancer.
Yujia Song, Xiaohui Wang, Yuqi Sun, Nianhua Yu, Yajie Tian, Xianjun Qu

Int J Biol Sci· October 2024

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Hydrogel and Nanomedicine-Based Multimodal Therapeutic Strategies for Spinal Cord Injury.
Peng Yin, Weishi Liang, Bo Han, Yihan Yang, Duan Sun, Xianjun Qu

Small Methods· January 2024

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PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood.
Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu

Mediators Inflamm· January 2024

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Novel ProTide prodrugs of 5-fluoro-2'-deoxyuridine for the treatment of liver cancer.
Leilei Jiang, Ting Pan, Qin Lv, Wenmin Yuan, Xiaochun Liu, Xianjun Qu

Eur J Med Chem· November 2023

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LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines.
Xiaoqian Wei, Shushan Pan, Zirui Wang, Jieru Chen, Li Lu, Xianjun Qu

Cell Death Dis· October 2023

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Translocation of IGF-1R in endoplasmic reticulum enhances SERCA2 activity to trigger Ca perturbation in hepatocellular carcinoma.
Yanan Li, Keqin Li, Ting Pan, Qiaobo Xie, Yuyao Cheng, Xianjun Qu

Acta Pharm Sin B· September 2023

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Activation of insulin-like growth factor-1 receptor (IGF-1R) promotes growth of colorectal cancer through triggering the MEX3A-mediated degradation of RIG-I.
Qiaobo Xie, Yanyan Chu, Wenmin Yuan, Yanan Li, Keqin Li, Xianjun Qu

Acta Pharm Sin B· July 2023

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Design, synthesis, and evaluation of JTE-013 derivatives as novel potent S1PR2 antagonists for recovering the sensitivity of colorectal cancer to 5-fluorouracil.
Zhikun Guo, Shuai Zhang, Xiaochun Liu, Guangjian Zhao, Yingzhi Zhang, Xianjun Qu

Bioorg Chem· February 2023

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Correction to "Rational Design, Synthesis, and Biological Evaluation of Novel S1PR2 Antagonists for Reversing 5-FU-Resistance in Colorectal Cancer".
Dongdong Luo, Xiaochun Liu, Leilei Jiang, Zhikun Guo, Yan Lv, Xianjun Qu

J Med Chem· December 2022

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Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Juan Yang, Rong-Rong Miao, Ya-Nan Li, Ting Pan, Shu-Hua Wu, Xian-Jun Qu

Acta Pharmacol Sin· November 2022

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Rational Design, Synthesis, and Biological Evaluation of Novel S1PR2 Antagonists for Reversing 5-FU-Resistance in Colorectal Cancer.
Dongdong Luo, Xiaochun Liu, Leilei Jiang, Zhikun Guo, Yan Lv, Xianjun Qu

J Med Chem· November 2022

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CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Mahan Si, Yujia Song, Xiaohui Wang, Dong Wang, Xiaohui Liu, Xianjun Qu

Cell Biosci· October 2022

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Intestinal aberrant sphingolipid metabolism shaped-gut microbiome and bile acids metabolome in the development of hepatic steatosis.
Rong-Rong Miao, Sheng Zhan, Shu-Xiang Cui, Xian-Jun Qu

FASEB J· August 2022

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Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Dong Wang, Xiaohui Wang, Yujia Song, Mahan Si, Yuqi Sun, Xianjun Qu

Cell Death Dis· April 2022

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ZnO nanoparticles promote the malignant transformation of colorectal epithelial cells in APC mice.
Jian Meng, Juan Yang, Ting Pan, Xianjun Qu, Shuxiang Cui

Environ Int· January 2022

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Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists.
Dongdong Luo, Zhikun Guo, Xuecui Zhao, Lijuan Wu, Xiaochun Liu, Xianjun Qu

Eur J Med Chem· January 2022

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Corrigendum to "Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages" [Canc. Lett. 474 (2020) 36-52].
Dong Wang, Xiaohui Wang, Mahan Si, Juan Yang, Shiyue Sun, Xianjun Qu

Cancer Lett· January 2022

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Design, synthesis and biological evaluation of sphingosine-1-phosphate receptor 2 antagonists as potent 5-FU-resistance reversal agents for the treatment of colorectal cancer.
Dongdong Luo, Yuhang Zhang, Shuang Yang, Xiaochen Tian, Yan Lv, Xianjun Qu

Eur J Med Chem· December 2021

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Myricetin and M10, a myricetin-3-O-β-d-lactose sodium salt, modify composition of gut microbiota in mice with ulcerative colitis.
Rong-Rong Miao, Sheng Zhan, Xue-Tao Hu, Wen-Min Yuan, Li-Juan Wu, Xian-Jun Qu

Toxicol Lett· August 2021

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