Publications by authors named "Xin Ku"

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Proteomic portrait of degranulation program in human circulating neutrophils upon multi-inflammatory and infectious activation.
Ying Hua, Ziqi Zhou, Can Zhang, Hai Fang, Mingxing Wu, Xin Ku

Mol Cell Proteomics· September 2025

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Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance.
Jinghan Wang, Xin Ku, Qiuling Ma, Haikuo Li, Sujuan Huang

Genes Dis· July 2024

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O-glycosylation of SARS-CoV-2 spike protein by host O-glycosyltransferase strengthens its trimeric structure.
Zhijue Xu, Han Zhang, Jiaqi Tian, Xin Ku, Rumeng Wei, Atsushi Kuno

Acta Biochim Biophys Sin (Shanghai)· July 2024

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Proteomic Portrait of Human Lymphoma Reveals Protein Molecular Fingerprint of Disease Specific Subtypes and Progression.
Xin Ku, Jinghan Wang, Haikuo Li, Chen Meng, Fang Yu

Phenomics· April 2023

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HNRNPA2B1 as a potential therapeutic target for thymic epithelial tumor recurrence: An integrative network analysis.
Ziyun Zhou, Yu Lu, Zhitao Gu, Qiangling Sun, Wentao Fang, Xin Ku

Comput Biol Med· March 2023

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Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target.
Severin Lechner, Martin Ian P Malgapo, Christian Grätz, Raphael R Steimbach, Agnes Baron, Xin Ku, Bernhard Kuster

Nat Chem Biol· August 2022

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Author Correction: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target.
Severin Lechner, Martin Ian P Malgapo, Christian Grätz, Raphael R Steimbach, Agnes Baron, Xin Ku, Bernhard Kuster

Nat Chem Biol· August 2022

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Leveraging Protein Dynamics to Identify Functional Phosphorylation Sites using Deep Learning Models.
Fei Zhu, Sijie Yang, Fanwang Meng, Yuxiang Zheng, Xin Ku

J Chem Inf Model· July 2022

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Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy.
Jingjing Shi, Xin Ku, Xia Zou, Jingli Hou, Wei Yan

Biochim Biophys Acta Gen Subj· October 2021

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O-linked N-acetylgalactosamine modification is present on the tumor suppressor p53.
Zhijue Xu, Xin Ku, Azusa Tomioka, Wenxian Xie, Tao Liang

Biochim Biophys Acta Gen Subj· August 2020

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In-Depth Characterization of Mass Spectrometry-Based Proteomic Profiles Revealed Novel Signature Proteins Associated with Liver Metastatic Colorectal Cancers.
Xin Ku, Yan Xu, Chunlin Cai, Yili Yang, Long Cui

Anal Cell Pathol (Amst)· May 2020

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Comprehensive Map of the Artemisia annua Proteome and Quantification of Differential Protein Expression in Chemotypes Producing High versus Low Content of Artemisinin.
Minghui Chen, Tingxiang Yan, Liyun Ji, Yu Dong, Simone Sidoli, Xin Ku

Proteomics· May 2020

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Deciphering tissue-based proteome signatures revealed novel subtyping and prognostic markers for thymic epithelial tumors.
Xin Ku, Qiangling Sun, Lei Zhu, Zhitao Gu, Yuchen Han

Mol Oncol· April 2020

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Data independent acquisition-mass spectrometry (DIA-MS)-based comprehensive profiling of bone metastatic cancers revealed molecular fingerprints to assist clinical classifications for bone metastasis of unknown primary (BMUP).
Xin Ku, Chunlin Cai, Yan Xu, Su Chen, Zhenhua Zhou

Transl Cancer Res· April 2020

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Discovering Protein Biomarkers from Clinical Peripheral Blood Mononuclear Cells Using Data-Independent Acquisition Mass Spectrometry.
Xin Ku, Wei Yan

Methods Mol Biol· July 2019

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Data-independent acquisition-based quantitative proteomic analysis reveals differences in host immune response of peripheral blood mononuclear cells to sepsis.
Yiqing Tong, Xin Ku, Chunrong Wu, Jianjun Liu, Chunhui Yang

Scand J Immunol· April 2019

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Exosomal proteome analysis of human plasma to monitor sepsis progression.
Yan Xu, Xin Ku, Chunrong Wu, Chunlin Cai, Jianguo Tang

Biochem Biophys Res Commun· May 2018

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Optimized chemical proteomics assay for kinase inhibitor profiling.
Guillaume Médard, Fiona Pachl, Benjamin Ruprecht, Susan Klaeger, Stephanie Heinzlmeir, Xin Ku, Thomas Kuehne, Bernhard Kuster

J Proteome Res· March 2015

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New affinity probe targeting VEGF receptors for kinase inhibitor selectivity profiling by chemical proteomics.
Xin Ku, Stephanie Heinzlmeir, Dominic Helm, Guillaume Médard, Bernhard Kuster

J Proteome Res· May 2014

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A new chemical probe for quantitative proteomic profiling of fibroblast growth factor receptor and its inhibitors.
Xin Ku, Stephanie Heinzlmeir, Xiaofeng Liu, Guillaume Médard, Bernhard Kuster

J Proteomics· January 2014

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Discovery of pteridin-7(8H)-one-based irreversible inhibitors targeting the epidermal growth factor receptor (EGFR) kinase T790M/L858R mutant.
Wei Zhou, Xiaofeng Liu, Zhengchao Tu, Lianwen Zhang, Xin Ku

J Med Chem· October 2013

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ChemMapper: a versatile web server for exploring pharmacology and chemical structure association based on molecular 3D similarity method.
Jiayu Gong, Chaoqian Cai, Xiaofeng Liu, Xin Ku, Hualiang Jiang

Bioinformatics· July 2013

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A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity.
He Huang, Qin Chen, Xin Ku, Linghua Meng, Liping Lin

J Med Chem· April 2010

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Efficient iron/copper cocatalyzed S-arylations of thiols with aryl halides.
Xin Ku, He Huang, Hualiang Jiang, Hong Liu

J Comb Chem· July 2009

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