Publications by authors named "Xuwang Chen"

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Selective MMP-13 Inhibitors: Promising Agents for the Therapy of Osteoarthritis.
Yichao Wan, Wei Li, Zhipeng Liao, Mi Yan, Xuwang Chen

Curr Med Chem· July 2020

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Pharmacokinetic, metabolic profiling and elimination of brusatol in rats.
Nan Guo, Xin Xu, Guiyan Yuan, Xuwang Chen, Qing Wen, Ruichen Guo

Biomed Chromatogr· December 2018

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A simple and economical method of gas chromatography-mass spectrometry to determine the presence of 6 pesticides in human plasma and its clinical application in patients with acute poisoning.
Guiyan Yuan, Rui Zhang, Xuwang Chen, Benjie Wang, Ruichen Guo

Biosci Trends· October 2018

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Comparison of the docetaxel concentration in human plasma measured with liquid chromatography-tandem mass spectrometry (LC-MS/MS) and a nanoparticle immunoassay and clinical applications of that assay.
Chunmei Geng, Pingli Li, Xuwang Chen, Guiyan Yuan, Nan Guo, Ruichen Guo

Biosci Trends· May 2017

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Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket.
Qing Meng, Xuwang Chen, Dongwei Kang, Boshi Huang, Wenxin Li

Eur J Med Chem· June 2016

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Recent advance of the hepatitis B virus inhibitors: a medicinal chemistry overview.
Haiyong Jia, Diwakar Rai, Peng Zhan, Xuwang Chen, Xuemei Jiang

Future Med Chem· January 2016

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Design, Synthesis, and Anti-HIV Evaluation of Novel Triazine Derivatives Targeting the Entrance Channel of the NNRTI Binding Pocket.
Xuwang Chen, Qing Meng, Liyun Qiu, Peng Zhan, Huiqing Liu

Chem Biol Drug Des· July 2015

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Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs.
Lingzi Zhang, Peng Zhan, Xuwang Chen, Zhenyu Li, Zhoumeng Xie

Bioorg Med Chem· January 2014

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Design, synthesis and biological evaluation of 3-benzyloxy-linked pyrimidinylphenylamine derivatives as potent HIV-1 NNRTIs.
Diwakar Rai, Wenmin Chen, Ye Tian, Xuwang Chen, Peng Zhan

Bioorg Med Chem· December 2013

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Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu

Bioorg Med Chem Lett· December 2013

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Recent advances of diaryl ether family as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Xuwang Chen, Shufang Ding, Peng Zhan, Xinyong Liu

Curr Pharm Des· September 2013

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Discovery of piperidine-linked pyridine analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque

ChemMedChem· July 2013

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HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and implications for drug design.
Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq

Med Res Rev· June 2013

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Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs.
Peng Zhan, Xiao Li, Zhenyu Li, Xuwang Chen, Ye Tian, Wenmin Chen

Bioorg Med Chem Lett· December 2012

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Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach.
Peng Zhan, Wenmin Chen, Zhenyu Li, Xiao Li, Xuwang Chen

Bioorg Med Chem· December 2012

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Arylazolyl(azinyl)thioacetanilides. Part 10: design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors.
Xiao Li, Peng Zhan, Hong Liu, Dongyue Li, Liu Wang, Xuwang Chen

Bioorg Med Chem· September 2012

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Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.
Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng

Bioorg Med Chem· June 2012

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Arylazolyl(azinyl)thioacetanilide. Part 9: Synthesis and biological investigation of thiazolylthioacetamides derivatives as a novel class of potential antiviral agents.
Peng Zhan, Liu Wang, Hong Liu, Xuwang Chen, Xiao Li

Arch Pharm Res· June 2012

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Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq

Eur J Med Chem· May 2012

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Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
Peng Zhan, Xuwang Chen, Xiao Li, Dongyue Li, Ye Tian, Wenwen Chen

Eur J Med Chem· October 2011

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Functional roles of azoles motif in anti-HIV agents.
Peng Zhan, Dongyue Li, Xuwang Chen, Xinyong Liu, Erik De Clercq

Curr Med Chem· May 2011

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Recent advances in DAPYs and related analogues as HIV-1 NNRTIs.
Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu

Curr Med Chem· May 2011

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