Publications by authors named "Yitzhak Zimmer"

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HPV and p53 Status as Precision Determinants of Head and Neck Cancer Response to DNA-PKcs Inhibition in Combination with Irradiation.
Liana Hayrapetyan, Selina M Roth, Aurélie Quintin, Lusine Hovhannisyan, Matúš Medo, Yitzhak Zimmer

Mol Cancer Ther· February 2025

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E2F1-Associated Purine Synthesis Pathway Is a Major Component of the MET-DNA Damage Response Network.
Michaela Poliaková Turan, Rahel Riedo, Matúš Medo, Chiara Pozzato, Manja Friese-Hamim, Yitzhak Zimmer

Cancer Res Commun· July 2024

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Author Correction: Tumour mutations in long noncoding RNAs enhance cell fitness.
Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Yitzhak Zimmer

Nat Commun· September 2023

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A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response.
Jonas P Koch, Selina M Roth, Aurélie Quintin, Jacopo Gavini, Eleonora Orlando, Yitzhak Zimmer

Oncogene· June 2023

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CAR T cell-based immunotherapy and radiation therapy: potential, promises and risks.
Lusine Hovhannisyan, Carsten Riether, Daniel M Aebersold, Michaela Medová, Yitzhak Zimmer

Mol Cancer· May 2023

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Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies.
Eleonora Orlando, Matúš Medo, Ariel Bensimon, Aurélie Quintin, Rahel Riedo, Yitzhak Zimmer

Cell Mol Life Sci· March 2023

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Beyond keratinocyte differentiation: emerging new biology of small proline-rich proteins.
Adam Zabini, Yitzhak Zimmer, Michaela Medová

Trends Cell Biol· January 2023

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An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies.
Eleonora Orlando, Matúš Medo, Ariel Bensimon, Aurélie Quintin, Rahel Riedo, Yitzhak Zimmer

Cell Mol Life Sci· December 2022

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Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review.
Daniel H Schanne, Alexander Koch, Olgun Elicin, Roland Giger, Michaela Medová, Yitzhak Zimmer

Biomedicines· December 2022

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Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury.
Nicolas Melin, Daniel Sánchez-Taltavull, René Fahrner, Adrian Keogh, Michel Dosch, Yitzhak Zimmer

Cell Death Dis· April 2021

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Enhancing CRISPR deletion via pharmacological delay of DNA-PKcs.
Núria Bosch-Guiteras, Tina Uroda, Hugo A Guillen-Ramirez, Rahel Riedo, Amiq Gazdhar, Yitzhak Zimmer

Genome Res· March 2021

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DNA-PK in human malignant disorders: Mechanisms and implications for pharmacological interventions.
Michaela Medová, Matúš Medo, Lusine Hovhannisyan, Carmen Muñoz-Maldonado, Daniel M Aebersold, Yitzhak Zimmer

Pharmacol Ther· November 2020

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Editorial: Exploiting DNA Damage Response in the Era of Precision Oncology.
Yitzhak Zimmer, Hans Christian Reinhardt, Michaela Medová

Front Oncol· October 2020

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Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomics.
Ariel Bensimon, Jonas P Koch, Paola Francica, Selina M Roth, Rahel Riedo, Yitzhak Zimmer

Mol Oncol· June 2020

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MET targeting: time for a rematch.
Jonas P Koch, Daniel M Aebersold, Yitzhak Zimmer, Michaela Medová

Oncogene· April 2020

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Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma.
Lluís Nisa, Paola Francica, Roland Giger, Matúš Medo, Olgun Elicin, Yitzhak Zimmer

Mol Cancer Ther· February 2020

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Verteporfin-induced lysosomal compartment dysregulation potentiates the effect of sorafenib in hepatocellular carcinoma.
Jacopo Gavini, Noëlle Dommann, Manuel O Jakob, Adrian Keogh, Laure C Bouchez, Yitzhak Zimmer

Cell Death Dis· October 2019

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A Comparative Analysis of Individual RAS Mutations in Cancer Biology.
Carmen Muñoz-Maldonado, Yitzhak Zimmer, Michaela Medová

Front Oncol· October 2019

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Metabolomics reveals tepotinib-related mitochondrial dysfunction in MET-activating mutations-driven models.
Michaela Poliaková, Andrea Felser, Katarzyna Pierzchala, Jean-Marc Nuoffer, Daniel Matthias Aebersold, Yitzhak Zimmer

FEBS J· July 2019

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Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase.
Eleonora Orlando, Daniel Matthias Aebersold, Michaela Medová, Yitzhak Zimmer

Cancer Lett· February 2019

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Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease.
Lluís Nisa, David Barras, Michaela Medová, Daniel M Aebersold, Matúš Medo, Yitzhak Zimmer

Mol Cancer Res· December 2018

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Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxia.
Astrid A Glück, Eleonora Orlando, Dominic Leiser, Michaela Poliaková, Lluís Nisa, Yitzhak Zimmer

Oncogene· July 2018

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The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer.
Michaela Poliaková, Daniel M Aebersold, Yitzhak Zimmer, Michaela Medová

Mol Cancer· February 2018

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PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models.
Lluís Nisa, Pascal Häfliger, Michaela Poliaková, Roland Giger, Paola Francica, Yitzhak Zimmer

Mol Cancer· May 2017

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