Publications by authors named "Yoshihiko Funae"

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Pravastatin-induced proangiogenic effects depend upon extracellular FGF-2.
Masayuki Shiota, Yuko Hikita, Yukiko Kawamoto, Hiromi Kusakabe, Masako Tanaka, Yoshihiko Funae

J Cell Mol Med· September 2012

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Progesterone induced mesenchymal differentiation and rescued cystic dilation of renal tubules of Pkd1(-/-) mice.
Tomoka Wachi, Noriyuki Yoshida, Yoshihiko Funae, Munehisa Ueno, Gregory G Germino

Biochem Biophys Res Commun· August 2012

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Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells.
Ami Oguro, Koichi Sakamoto, Yoshihiko Funae, Susumu Imaoka

Drug Metab Pharmacokinet· February 2012

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Coadministration of carvedilol attenuates nitrate tolerance by preventing cytochrome p450 depletion.
Atsushi Nakahira, Yukiko Minamiyama, Shigekazu Takemura, Hidekazu Hirai, Yasuyuki Sasaki, Yoshihiko Funae

Circ J· August 2010

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LKM-1 sera from autoimmune hepatitis patients that recognize ERp57, carboxylesterase 1 and CYP2D6.
Ryo Komurasaki, Susumu Imaoka, Naomichi Tada, Kazushi Okada, Shuhei Nishiguchi, Yoshihiko Funae

Drug Metab Pharmacokinet· June 2010

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Heat shock cognate protein 70 is essential for Akt signaling in endothelial function.
Masayuki Shiota, Hiromi Kusakabe, Yasukatsu Izumi, Yuko Hikita, Takafumi Nakao, Yoshihiko Funae

Arterioscler Thromb Vasc Biol· March 2010

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Hydroxylated polychlorinated biphenyls (PCBs) interact with protein disulfide isomerase and inhibit its activity.
Kazushi Okada, Shoko Hashimoto, Yoshihiko Funae, Susumu Imaoka

Chem Res Toxicol· May 2009

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The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol.
Shizuo Narimatsu, Daichi Kazamori, Kazufumi Masuda, Takashi Katsu, Yoshihiko Funae

Biochem Pharmacol· March 2009

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Epoxyeicosatrienoic acids and/or their metabolites promote hypoxic response of cells.
Sachiko Suzuki, Ami Oguro, Mayuko Osada-Oka, Yoshihiko Funae, Susumu Imaoka

J Pharmacol Sci· September 2008

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Analysis of gene and protein expression of cytochrome P450 and stress-associated molecules in rat liver after spaceflight.
Taisuke Baba, Masuhiro Nishimura, Yoshikazu Kuwahara, Nobuhiko Ueda, Shinsaku Naitoh, Yoshihiko Funae

Pathol Int· September 2008

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The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.
Shizuo Narimatsu, Kimio Kiryu, Rei Yonemoto, Manabu Yoshino, Mitsuko Kobatake, Yoshihiko Funae

Chem Biol Interact· March 2008

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Effect of psychotropic drugs on the 21-hydroxylation of neurosteroids, progesterone and allopregnanolone, catalyzed by rat CYP2D4 and human CYP2D6 in the brain.
Toshiro Niwa, Kazushi Okada, Toyoko Hiroi, Susumu Imaoka, Shizuo Narimatsu, Yoshihiko Funae

Biol Pharm Bull· March 2008

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Overexpression of CYP3A aggravates endotoxin-induced liver injury in hypophysectomized female rats.
Shigekazu Takemura, Yukiko Minamiyama, Shinya Toyokuni, Susumu Imaoka, Seikan Hai, Yoshihiko Funae

Hepatol Res· January 2008

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Over-expression of protein disulfide isomerase reduces the release of growth hormone induced by bisphenol A and/or T3.
Kazushi Okada, Susumu Imaoka, Shoko Hashimoto, Toyoko Hiroi, Yoshihiko Funae

Mol Cell Endocrinol· November 2007

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Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors.
Tsutomu Shimada, Norie Murayama, Kazushi Okada, Yoshihiko Funae, Hiroshi Yamazaki

Chem Res Toxicol· March 2007

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Cytochrome P450 is responsible for nitric oxide generation from NO-aspirin and other organic nitrates.
Yukiko Minamiyama, Shigekazu Takemura, Susumu Imaoka, Yoshihiko Funae, Shigeru Okada

Drug Metab Pharmacokinet· February 2007

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Nicorandil elevates tissue cGMP levels in a nitric-oxide-independent manner.
Yukiko Minamiyama, Shigekazu Takemura, Seikan Hai, Shigefumi Suehiro, Shigeru Okada, Yoshihiko Funae

J Pharmacol Sci· January 2007

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CYP2A13 expressed in human bladder metabolically activates 4-aminobiphenyl.
Miki Nakajima, Masahiro Itoh, Haruko Sakai, Tatsuki Fukami, Miki Katoh, Yoshihiko Funae

Int J Cancer· December 2006

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Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes.
Rawiwan Puatanachokchai, Keiichirou Morimura, Hideki Wanibuchi, Mayuko Oka, Anna Kinoshita, Yoshihiko Funae

Cancer Lett· August 2006

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Recovery of hepatic function determined by cytochrome P450-dependent drug metabolism lags after compensatory hepatic volume changes after portal vein ligation in rats.
Shigekazu Takemura, Yukiko Minamiyama, Kazuhiro Hirohashi, Shoji Kubo, Yoshihiko Funae

J Surg Res· August 2006

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Bisphenol A binds to protein disulfide isomerase and inhibits its enzymatic and hormone-binding activities.
Toyoko Hiroi, Kazushi Okada, Susumu Imaoka, Mayuko Osada, Yoshihiko Funae

Endocrinology· June 2006

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A new epitope of CYP2D6 recognized by liver kidney microsomal autoantibody from japanese patients with autoimmune hepatitis.
Susumu Imaoka, Noriko Obata, Toyoko Hiroi, Mayuko Osada-Oka, Rie Hara, Yoshihiko Funae

Biol Pharm Bull· December 2005

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Localization of rat cytochrome P450 in various tissues and comparison of arachidonic acid metabolism by rat P450 with that by human P450 orthologs.
Susumu Imaoka, Takanori Hashizume, Yoshihiko Funae

Drug Metab Pharmacokinet· December 2005

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Inhibitory effects of environmental chemicals on protein disulfide isomerase in vitro.
Kazushi Okada, Toyoko Hiroi, Susumu Imaoka, Yoshihiko Funae

Osaka City Med J· December 2005

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Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol: evidence for a threshold.
Masahiko Kushida, Hideki Wanibuchi, Keiichirou Morimura, Anna Kinoshita, Jin Seok Kang, Yoshihiko Funae

Cancer Sci· November 2005

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