Publications by authors named "You-Hong Fan"

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Molecular basis of microRNA stability and degradation in plants.
Meng-Wei Guo, You-Hong Fan, Guo-Dong Ren

Yi Chuan· August 2025

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Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer.
Kasey R Cargill, C Allison Stewart, Elizabeth M Park, Kavya Ramkumar, Carl M Gay, You-Hong Fan

Cancer Metab· September 2021

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Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.
Xiuning Le, Marcelo V Negrao, Alexandre Reuben, Lorenzo Federico, Lixia Diao, You-Hong Fan

J Thorac Oncol· April 2021

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AXL Inhibition Induces DNA Damage and Replication Stress in Non-Small Cell Lung Cancer Cells and Promotes Sensitivity to ATR Inhibitors.
Kavya Ramkumar, C Allison Stewart, Kasey R Cargill, Carminia M Della Corte, Qi Wang, You-Hong Fan

Mol Cancer Res· March 2021

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Patterns of protein expression in human head and neck cancer cell lines differ after proton vs photon radiotherapy.
Li Wang, Liuqing Yang, Shichao Han, Jinming Zhu, Yuting Li, You-Hong Fan

Head Neck· February 2020

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Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer.
Pierre Saintigny, William N William, Jean-Philippe Foy, Vassiliki Papadimitrakopoulou, Wenhua Lang, You Hong Fan

J Natl Cancer Inst· March 2018

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Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies.
Robert J Cardnell, Lerong Li, Triparna Sen, Rasha Bara, Pan Tong, You-Hong Fan

Oncotarget· September 2017

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CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib.
Triparna Sen, Pan Tong, C Allison Stewart, Sandra Cristea, Aly Valliani, You Hong Fan

Cancer Res· July 2017

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Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer.
Heath D Skinner, Uma Giri, Liang P Yang, Manish Kumar, Ying Liu, You Hong Fan

Clin Cancer Res· June 2017

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Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer.
Heath D Skinner, Uma Giri, Liang Yang, Sang Hyeok Woo, Michael D Story, You Hong Fan

Clin Cancer Res· September 2016

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Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer.
Robert J Cardnell, Ying Feng, Seema Mukherjee, Lixia Diao, Pan Tong, YouHong Fan

PLoS One· August 2016

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Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma.
Yanyan Lou, Lixia Diao, Edwin Roger Parra Cuentas, Warren L Denning, Limo Chen, You Hong Fan

Clin Cancer Res· July 2016

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8-Chloroadenosine Sensitivity in Renal Cell Carcinoma Is Associated with AMPK Activation and mTOR Pathway Inhibition.
Alper Y Kearney, You-Hong Fan, Uma Giri, Babita Saigal, Varsha Gandhi

PLoS One· May 2016

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An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.
Robert J G Cardnell, Carmen Behrens, Lixia Diao, YouHong Fan, Ximing Tang

Clin Cancer Res· August 2015

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A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma.
Tuhina Mazumdar, Lauren A Byers, Patrick Kwok Shing Ng, Gordon B Mills, Shaohua Peng, You-Hong Fan

Mol Cancer Ther· November 2014

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Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer.
Robert J Cardnell, Ying Feng, Lixia Diao, You-Hong Fan, Fatemah Masrorpour

Clin Cancer Res· November 2013

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Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling.
Humam Kadara, Li Shen, Junya Fujimoto, Pierre Saintigny, Chi-Wan Chow, You-Hong Fan

Cancer Prev Res (Phila)· January 2013

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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
Lauren Averett Byers, Jing Wang, Monique B Nilsson, Junya Fujimoto, Pierre Saintigny, You Hong Fan

Cancer Discov· September 2012

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Gene expression profiling predicts the development of oral cancer.
Pierre Saintigny, Li Zhang, You-Hong Fan, Adel K El-Naggar, Vassiliki A Papadimitrakopoulou

Cancer Prev Res (Phila)· February 2011

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Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer.
Mohammed Taoudi Benchekroun, Pierre Saintigny, Sufi M Thomas, Adel K El-Naggar, Vassiliki Papadimitrakopoulou, You-Hong Fan

Cancer Prev Res (Phila)· July 2010

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DeltaNp63 overexpression, alone and in combination with other biomarkers, predicts the development of oral cancer in patients with leukoplakia.
Pierre Saintigny, Adel K El-Naggar, Vali Papadimitrakopoulou, Hening Ren, You-Hong Fan

Clin Cancer Res· October 2009

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Impact of smoking cessation on global gene expression in the bronchial epithelium of chronic smokers.
Li Zhang, J Jack Lee, Hongli Tang, You-Hong Fan, Lianchun Xiao

Cancer Prev Res (Phila)· July 2008

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Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the lungs.
Manisha Bhutani, Ashutosh Kumar Pathak, You-Hong Fan, Diane D Liu, J Jack Lee

Cancer Prev Res (Phila)· June 2008

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Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy.
Hidetoshi Kawaguchi, Adel K El-Naggar, Vali Papadimitrakopoulou, Hening Ren, You-Hong Fan

J Clin Oncol· January 2008

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In vitro expression levels of cell-cycle checkpoint proteins are associated with cellular DNA repair capacity in peripheral blood lymphocytes: a multivariate analysis.
You-Hong Fan, Zhibin Hu, Chunying Li, Li-E Wang, Zhaozheng Guo

J Proteome Res· April 2007

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