Publications by authors named "You-Take Oh"

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Spatially resolved subcellular protein-protein interactomics in drug-perturbed lung-cancer cultures and tissues.
Shuangyi Cai, Thomas Hu, Abhijeet Venkataraman, Felix G Rivera Moctezuma, Efe Ozturk, You-Take Oh

Nat Biomed Eng· July 2025

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Induction of IL6/STAT3-dependent TRAIL expression that contributes to the therapeutic efficacy of osimertinib in EGFR mutant NSCLC cells.
You-Take Oh, Zhen Chen, Dongsheng Wang, Suresh S Ramalingam, Shi-Yong Sun

Oncogene· July 2025

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Rictor, an essential component of mTOR complex 2, undergoes caspase-mediated cleavage during apoptosis induced by multiple stimuli.
Liqun Zhao, Lei Zhu, You-Take Oh, Guoqing Qian, Zhen Chen

Apoptosis· June 2021

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Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling.
You-Take Oh, Shi-Yong Sun

Biomolecules· March 2021

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RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization.
Jian Wang, You-Take Oh, Zhentian Li, Juan Dou, Siyuan Tang

Cell Rep· January 2021

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Correction: Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.
You-Take Oh, Ping Yue, Wei Zhou, Justin M Balko, Esther P Black

J Biol Chem· June 2020

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Correction: Expression of death receptor 4 is positively regulated by MEK/ERK/AP-1 signaling and suppressed upon MEK inhibition.
Weilong Yao, You-Take Oh, Jiusheng Deng, Ping Yue, Liang Deng

J Biol Chem· June 2020

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Ionizing radiation-induced growth in soft agar is associated with miR-21 upregulation in wild-type and DNA double strand break repair deficient cells.
Siyuan Tang, Bailong Liu, Min Liu, Zhentian Li, Jiaqi Liu, You-Take Oh

DNA Repair (Amst)· June 2019

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Monocyte chemotactic protein-induced protein-1 enhances DR5 degradation and negatively regulates DR5 activation-induced apoptosis through its deubiquitinase function.
You-Take Oh, Guoqing Qian, Jiusheng Deng, Shi-Yong Sun

Oncogene· June 2018

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Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation.
Puyu Shi, You-Take Oh, Liang Deng, Guojing Zhang, Guoqing Qian

Clin Cancer Res· November 2017

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The proteasome deubiquitinase inhibitor b-AP15 enhances DR5 activation-induced apoptosis through stabilizing DR5.
You-Take Oh, Liang Deng, Jiusheng Deng, Shi-Yong Sun

Sci Rep· August 2017

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DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion.
You-Take Oh, Ping Yue, Shi-Yong Sun

Cell Commun Signal· May 2017

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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
Puyu Shi, You-Take Oh, Guojing Zhang, Weilong Yao, Ping Yue

Cancer Lett· October 2016

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Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition.
Weilong Yao, You-Take Oh, Jiusheng Deng, Ping Yue, Liang Deng

J Biol Chem· October 2016

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Paradoxical activation of MEK/ERK signaling induced by B-Raf inhibition enhances DR5 expression and DR5 activation-induced apoptosis in Ras-mutant cancer cells.
You-Take Oh, Jiusheng Deng, Ping Yue, Shi-Yong Sun

Sci Rep· May 2016

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Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling.
You-Take Oh, Ping Yue, Dongsheng Wang, Jing-Shan Tong, Zhuo G Chen

Oncotarget· December 2015

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The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5.
Bo Han, Weilong Yao, You-Take Oh, Jing-Shan Tong, Shaohua Li

Oncotarget· July 2015

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Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.
You-Take Oh, Ping Yue, Wei Zhou, Justin M Balko, Esther P Black

J Biol Chem· January 2012

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Establishment of novel cell lines latently infected with human immunodeficiency virus 1.
You-Take Oh, Kyung-Chang Kim, Kee-Jong Hong, Hak-Sung Lee, Dae-Ho Jang

Acta Virol· September 2011

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ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1.
You-Take Oh, Xiangguo Liu, Ping Yue, Sumin Kang, Jing Chen

J Biol Chem· December 2010

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Novel histone deacetylase inhibitors CG05 and CG06 effectively reactivate latently infected HIV-1.
Byeong-Sun Choi, Hak Sung Lee, You-Take Oh, Young-Lan Hyun, Sunggu Ro

AIDS· February 2010

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Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced apoptosis.
Joon-Seok Choi, Soona Shin, Ying Hua Jin, Hyungshin Yim, Kyo-Tan Koo, You-Take Oh

Apoptosis· July 2007

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Regulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1 by protein kinase Cdelta-mediated phosphorylation.
You-Take Oh, Kwang Hoon Chun, Byoung Duck Park, Joon-Seok Choi, Seung Ki Lee

Apoptosis· July 2007

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PKCdelta modulates p21WAF1/CIP1 ability to bind to Cdk2 during TNFalpha-induced apoptosis.
You-Take Oh, Kwang Hoon Chun, Jeong In Oh, Jeong Ae Park, Yong Ung Kim

Biochem Biophys Res Commun· January 2006

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Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells.
Jeong-In Oh, Kwang-Hoon Chun, Sang-Hoon Joo, You-Take Oh, Seung-Ki Lee

Cancer Lett· December 2005

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