Publications by authors named "Yousef Alhammad"

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Mutations differentially affecting the coronavirus Mac1 ADP-ribose binding and hydrolysis activities indicate that it promotes multiple stages of the viral replication cycle.
Joseph J O'Connor, Anuradha Roy, Reem Khattabi, Catherine Kerr, Nancy Schwarting, Yousef M Alhammad

J Virol· August 2025

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Laryngoscopic evaluation of arytenoid movements in pure Arabian horses.
Ghaliah Al Shehab, Razan Naji, Fatimah Alali, Anfal Alali, Ahmad Allowaim, Yousef M A Alhammad

Open Vet J· June 2025

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Mutation of a highly conserved isoleucine residue in loop 2 of several β-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental for replication.
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M Alhammad, Joseph J O'Connor, Roshan Ghimire

J Virol· November 2024

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Pharmacological inhibition of ENT1 enhances the impact of specific dietary fats on energy metabolism gene expression.
Erwann Pain, Stuart Snowden, Joseph Oddy, Sonia Shinhmar, Yousef M A Alhammad

Proc Natl Acad Sci U S A· September 2024

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Mutation of a highly conserved isoleucine residue in loop 2 of several -coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection.
Catherine M Kerr, Jessica J Pfannenstiel, Yousef M Alhammad, Joseph J O'Connor, Roshan Ghimire

bioRxiv· July 2024

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SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice.
Yousef M Alhammad, Srivatsan Parthasarathy, Roshan Ghimire, Catherine M Kerr, Joseph J O'Connor

Proc Natl Acad Sci U S A· August 2023

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SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice.
Yousef M Alhammad, Srivatsan Parthasarathy, Roshan Ghimire, Joseph J O'Connor, Catherine M Kerr

bioRxiv· April 2023

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Full-Length Genome of the Equine Influenza A Virus Subtype H3N8 from 2019 Outbreak in Saudi Arabia.
Fanan A Alaql, Ali N Alhafufi, Samy Kasem, Yousef M O Alhammad, Hassan Albaqshi

Animals (Basel)· October 2022

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Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain.
Lavinia M Sherrill, Elva E Joya, AnnMarie Walker, Anuradha Roy, Yousef M Alhammad

Bioorg Med Chem· August 2022

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Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening.
Anu Roy, Yousef M Alhammad, Peter McDonald, David K Johnson, Junlin Zhuo

Antiviral Res· July 2022

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Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening.
Anu Roy, Yousef M Alhammad, Peter McDonald, David K Johnson, Junlin Zhuo

bioRxiv· March 2022

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Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain.
Lavinia M Sherrill, Elva E Joya, AnnMarie Walker, Anuradha Roy, Yousef M Alhammad

bioRxiv· February 2022

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High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain.
Morgan Dasovich, Junlin Zhuo, Jack A Goodman, Ajit Thomas, Robert Lyle McPherson, Yousef M O Alhammad

ACS Chem Biol· January 2022

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The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.
Yousef M O Alhammad, Maithri M Kashipathy, Anuradha Roy, Jean-Philippe Gagné, Peter McDonald

J Virol· January 2021

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.
Collin D Heer, Daniel J Sanderson, Lynden S Voth, Yousef M O Alhammad, Mark S Schmidt

J Biol Chem· December 2020

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Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity.
Collin D Heer, Daniel J Sanderson, Lynden S Voth, Yousef M O Alhammad, Mark S Schmidt

bioRxiv· October 2020

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The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase.
Yousef M O Alhammad, Maithri M Kashipathy, Anuradha Roy, Jean-Philippe Gagné, Peter McDonald

bioRxiv· October 2020

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The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation.
Yousef M O Alhammad, Anthony R Fehr

Viruses· March 2020

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Circulation of Influenza A(H5N8) Virus, Saudi Arabia.
Hussain Al-Ghadeer, Daniel K W Chu, Ehab M A Rihan, Ehab A Abd-Allah, Haogao Gu, Yousef M O Alhammad

Emerg Infect Dis· October 2018

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Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes.
Jun Gu, Joshua Hardy, Irene Boo, Patricia Vietheer, Kathleen McCaffrey, Yousef Alhammad

J Virol· May 2018

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Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection.
Yousef M O Alhammad, Sanvir Maharajh, Rebecca Butcher, John-Sebastian Eden, Peter A White

PLoS One· February 2016

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Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region.
Yousef Alhammad, Jun Gu, Irene Boo, David Harrison, Kathleen McCaffrey

J Virol· December 2015

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