Publications by authors named "Youyi Peng"

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A Weldable, Low-Cost Graphite-Based Electrode for Mn/MnO Redox Chemistry with High Volumetric Energy Density.
Zeqin Hu, Jianjun Su, Yiting Li, Youyi Peng, Rui Zhang

Small· December 2025

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BMP receptor 2 inhibition regulates mitochondrial bioenergetics to induce synergistic cell death with BCL-2 inhibitors in leukemia and NSLC cells.
Ashley Toussaint, Manohar Singh, Guoquiang Wang, Monica Driscoll, Vrushank Bhatt, Youyi Peng

Res Sq· September 2024

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Preclinical Evaluation of Sigma 1 Receptor Antagonists as a Novel Treatment for Painful Diabetic Neuropathy.
Youyi Peng, Allen H Zhang, Liping Wei, William J Welsh

ACS Pharmacol Transl Sci· August 2024

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Recent advances in drug discovery efforts targeting the sigma 1 receptor system: Implications for novel medications designed to reduce excessive drug and food seeking.
Liam G Knowles, Abanoub J Armanious, Youyi Peng, William J Welsh, Morgan H James

Addict Neurosci· December 2023

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Bone morphogenetic protein inhibitors and mitochondria targeting agents synergistically induce apoptosis-inducing factor (AIF) caspase-independent cell death in lung cancer cells.
Arindam Mondal, Jacques Roberge, John Gilleran, Youyi Peng, Dongxuan Jia

Cell Commun Signal· June 2022

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Bone morphogenetic protein receptor 2 inhibition destabilizes microtubules promoting the activation of lysosomes and cell death of lung cancer cells.
Arindam Mondal, Rachel NeMoyer, Mehul Vora, Logan Napoli, Zoya Syed, Youyi Peng

Cell Commun Signal· September 2021

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QSAR-Based Computational Approaches to Accelerate the Discovery of Sigma-2 Receptor (S2R) Ligands as Therapeutic Drugs.
Yangxi Yu, Hiep Dong, Youyi Peng, William J Welsh

Molecules· August 2021

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Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management.
Youyi Peng, Qiang Zhang, William J Welsh

J Med Chem· January 2021

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Identification of an irreversible PPARγ antagonist with potent anticancer activity.
Youyi Peng, Qiang Zhang, Robert M Zielinski, Richard D Howells, William J Welsh

Pharmacol Res Perspect· December 2020

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Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein.
Rachel NeMoyer, Arindam Mondal, Mehul Vora, Elaine Langenfeld, Danea Glover, Youyi Peng

Cell Commun Signal· November 2019

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Antagonizing α7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition.
Nick P van Goethem, Dean Paes, Daniela Puzzo, Ernesto Fedele, Claudia Rebosio, Youyi Peng

Cell Signal· October 2019

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Comprehensive 3D-QSAR Model Predicts Binding Affinity of Structurally Diverse Sigma 1 Receptor Ligands.
Youyi Peng, Hiep Dong, William J Welsh

J Chem Inf Model· January 2019

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Phosphodiesterase 1: A Unique Drug Target for Degenerative Diseases and Cognitive Dysfunction.
Lawrence P Wennogle, Helen Hoxie, Youyi Peng, Joseph P Hendrick

Adv Neurobiol· January 2018

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Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity.
Stanley G Kimani, Sushil Kumar, Nitu Bansal, Kamalendra Singh, Vladyslav Kholodovych, Youyi Peng

Sci Rep· March 2017

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Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.
Peng Li, Qiang Zhang, Albert J Robichaud, Taekyu Lee, John Tomesch, Youyi Peng

J Med Chem· March 2014

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Discovery of novel alpha7 nicotinic receptor antagonists.
Youyi Peng, Qiang Zhang, Gretchen L Snyder, Hongwen Zhu, Wei Yao

Bioorg Med Chem Lett· August 2010

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Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain.
Hongwen Zhu, Jennifer J O'Brien, James P O'Callaghan, Diane B Miller, Qiang Zhang, Youyi Peng

Brain Res· June 2010

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Synthesis and antiproliferative activity of 7-azaindirubin-3'-oxime, a 7-aza isostere of the natural indirubin pharmacophore.
Marina Kritsanida, Prokopios Magiatis, Alexios-Leandros Skaltsounis, Youyi Peng, Peng Li

J Nat Prod· December 2009

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Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.
Youyi Peng, Qiang Zhang, Sonia Arora, Susan M Keenan, Sandhya Kortagere

Bioorg Med Chem· September 2009

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Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.
Sonia Arora, Xin I Wang, Susan M Keenan, Christina Andaya, Qiang Zhang, Youyi Peng

Cancer Res· March 2009

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Highly potent triazole-based tubulin polymerization inhibitors.
Qiang Zhang, Youyi Peng, Xin I Wang, Susan M Keenan, Sonia Arora

J Med Chem· February 2007

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Discovery of novel triazole-based opioid receptor antagonists.
Qiang Zhang, Susan M Keenan, Youyi Peng, Anil C Nair, Seong Jae Yu

J Med Chem· July 2006

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3D-QSAR comparative molecular field analysis on delta opioid receptor agonist SNC80 and its analogs.
Youyi Peng, Susan M Keenan, Qiang Zhang, William J Welsh

J Mol Graph Model· September 2005

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Structural model of the Plasmodium CDK, Pfmrk, a novel target for malaria therapeutics.
Youyi Peng, Susan M Keenan, William J Welsh

J Mol Graph Model· September 2005

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3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies.
Youyi Peng, Susan M Keenan, Qiang Zhang, Vladyslav Kholodovych, William J Welsh

J Med Chem· March 2005

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