Publications by authors named "Yue Webster"

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The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment.
Giulia Callegaro, Steven J Kunnen, Panuwat Trairatphisan, Solène Grosdidier, Marije Niemeijer, Yue W Webster

Arch Toxicol· December 2021

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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib.
Wayne D Blosser, Jack A Dempsey, Ann M McNulty, Xi Rao, Philip J Ebert, Yue Wang Webster

Oncotarget· January 2020

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Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.
Jian Du, Lei Yan, Raquel Torres, Xueqian Gong, Huimin Bian, Yue W Webster

Mol Cancer Ther· December 2019

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A Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results.
Jeffrey J Sutherland, James L Stevens, Kamin Johnson, Navin Elango, Yue W Webster

Toxicol Sci· August 2019

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Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the Tumor Suppressor Gene.
Xueqian Gong, Jian Du, Stephen H Parsons, Farhana F Merzoug, Yue Webster

Cancer Discov· February 2019

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Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling.
Michele Dowless, Caitlin D Lowery, Terry Shackleford, Matthew Renschler, Jennifer Stephens, Yue Webster

Clin Cancer Res· December 2018

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Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib.
Xueqian Gong, Lacey M Litchfield, Yue Webster, Li-Chun Chio, Swee Seong Wong

Cancer Cell· December 2017

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Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with or Mutations.
Yung-Mae M Yao, Gregory P Donoho, Philip W Iversen, Youyan Zhang, Robert D Van Horn, Yue Wang Webster

Clin Cancer Res· September 2017

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Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
Sheng-Bin Peng, James R Henry, Michael D Kaufman, Wei-Ping Lu, Bryan D Smith, Yue Webster

Cancer Cell· September 2015

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Leveraging health social networking communities in translational research.
Yue W Webster, Ernst R Dow, Jacob Koehler, Ranga C Gudivada, Mathew J Palakal

J Biomed Inform· August 2011

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The role of translational bioinformatics in drug discovery.
Natalie S Buchan, Deepak K Rajpal, Yue Webster, Carlos Alatorre, Ranga Chandra Gudivada

Drug Discov Today· May 2011

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Structure-guided expansion of kinase fragment libraries driven by support vector machine models.
Jon A Erickson, Mary M Mader, Ian A Watson, Yue W Webster, Richard E Higgs

Biochim Biophys Acta· March 2010

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GPU accelerated support vector machines for mining high-throughput screening data.
Quan Liao, Jibo Wang, Yue Webster, Ian A Watson

J Chem Inf Model· December 2009

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Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.
Michal Vieth, Jon Erickson, Jibo Wang, Yue Webster, Mary Mader

J Med Chem· October 2009

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