Publications by authors named "Yuk-Ching Tse-Dinh"

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The SWIB domain-containing DNA topoisomerase I of mediates DNA relaxation.
Li Shen, Abigail R Swoboda, Caitlynn Diggs, Shomita Ferdous, Andrew Terrebonne, Yuk-Ching Tse-Dinh

J Bacteriol· September 2025

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Search for Specific Inhibitors Targeting Type IA Topoisomerases.
Somaia Haque Chadni, Shomita Ferdous, Yuk-Ching Tse-Dinh

J Mol Biol· July 2025

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Networked Salt-Bridges Mediate Magnesium-Dependent Conformational Dynamics and Functional Regulation in Type IA Topoisomerases.
Yeonee Seol, Yuk-Ching Tse-Dinh, Keir C Neuman

Res Sq· July 2025

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Substituted Triazole-3,5-Diamine Compounds as Novel Human Topoisomerase III Beta Inhibitors.
Yasir Mamun, Somaia Haque Chadni, Ramanjaneyulu Rayala, Hasham Shafi, Shomita Ferdous, Yuk-Ching Tse-Dinh

Int J Mol Sci· June 2025

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Bacterial Topoisomerase I Growth Complementation Assay.
Thirunavukkarasu Annamalai, Yuk-Ching Tse-Dinh

Methods Mol Biol· May 2025

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Identification of novel human topoisomerase III beta inhibitors.
Yasir Mamun, Somaia Haque Chadni, Ramanjaneyulu Rayala, Shomita Ferdous, Rudramani Pokhrel, Yuk-Ching Tse-Dinh

bioRxiv· March 2025

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Substrate binding of human and bacterial type IA topoisomerase: An experimentation with AlphaFold 3.0.
Yasir Mamun, Ally Aguado, Ana Preza, Abhilasha Kadel, Anjani Mogallur, Yuk-Ching Tse-Dinh

Comput Struct Biotechnol J· March 2025

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The SWIB domain-containing DNA topoisomerase I of mediates DNA relaxation.
Li Shen, Caitlynn Diggs, Shomita Ferdous, Amanda Santos, Neol Wolf, Yuk-Ching Tse-Dinh

bioRxiv· December 2024

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Small Molecule Inhibitors of Topoisomerase I Identified by Machine Learning and In Vitro Assays.
Somaia Haque Chadni, Matthew A Young, Pedro Igorra, Md Anisur Rahman Bhuiyan, Victor Kenyon, Yuk-Ching Tse-Dinh

Int J Mol Sci· November 2024

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Insights into the DNA and RNA Interactions of Human Topoisomerase III Beta Using Molecular Dynamics Simulations.
Yasir Mamun, Yuk-Ching Tse-Dinh, Prem Chapagain

J Chem Inf Model· August 2024

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Characterization and antimicrobial activity of endophytic fungi from medicinal plant Agave americana.
Ganesh Khadka, Kateel G Shetty, Thirunavukkarasu Annamalai, Yuk-Ching Tse-Dinh, Krish Jayachandran

Lett Appl Microbiol· March 2024

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Variation of Structure and Cellular Functions of Type IA Topoisomerases across the Tree of Life.
Kemin Tan, Yuk-Ching Tse-Dinh

Cells· March 2024

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The interaction between transport-segment DNA and topoisomerase IA-crystal structure of MtbTOP1 in complex with both G- and T-segments.
Shomita Ferdous, Tumpa Dasgupta, Thirunavukkarasu Annamalai, Kemin Tan, Yuk-Ching Tse-Dinh

Nucleic Acids Res· January 2023

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Potent Inhibition of Bacterial DNA Gyrase by Digallic Acid and Other Gallate Derivatives.
Eddy E Alfonso, Rogelio Troche, Zifang Deng, Thirunavukkarasu Annamalai, Prem Chapagain, Yuk-Ching Tse-Dinh

ChemMedChem· December 2022

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Localization of topoisomerase I C-terminal sequence motif required for inhibition by endogenous toxin MazF4.
Pamela K Garcia, Rosemarie Martinez Borrero, Thirunavukkarasu Annamalai, Esnel Diaz, Steve Balarezo, Yuk-Ching Tse-Dinh

Front Microbiol· December 2022

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Proton Motive Force-Disrupting Antimycobacterial Guanylurea Polymer.
Michelle Miranda-Velez, Golam Sabbir Sarker, Priya Ramisetty, Sandra Geden, Priscila Cristina Bartolomeu Halicki, Yuk-Ching Tse-Dinh

Biomacromolecules· November 2022

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Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and Combination.
Brenda Diaz, Christopher Mederos, Kemin Tan, Yuk-Ching Tse-Dinh

Int J Mol Sci· August 2022

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A Yeast-Based Screening System for Differential Identification of Poisons and Suppressors of Human Topoisomerase I.
Ahmed Seddek, Christian Madeira, Thirunavukkarasu Annamalai, Christopher Mederos, Purushottam B Tiwari, Yuk-Ching Tse-Dinh

Front Biosci (Landmark Ed)· March 2022

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Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes.
Shar-Yin N Huang, Stephanie A Michaels, Brianna B Mitchell, Nadim Majdalani, Arnaud Vanden Broeck, Yuk-Ching Tse-Dinh

Sci Adv· March 2021

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Trapped Ion Mobility Spectrometry of Native Macromolecular Assemblies.
Kevin Jeanne Dit Fouque, Alyssa Garabedian, Fenfei Leng, Yuk-Ching Tse-Dinh, Mark E Ridgeway

Anal Chem· February 2021

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Type IA Topoisomerases as Targets for Infectious Disease Treatments.
Ahmed Seddek, Thirunavukkarasu Annamalai, Yuk-Ching Tse-Dinh

Microorganisms· January 2021

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DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.
Sourav Saha, Yilun Sun, Shar-Yin Naomi Huang, Simone Andrea Baechler, Lorinc Sandor Pongor, Yuk-Ching Tse-Dinh

Cell Rep· December 2020

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A diverse global fungal library for drug discovery.
Guodong Niu, Thirunavukkarasu Annamalai, Xiaohong Wang, Sheng Li, Stephen Munga, Yuk-Ching Tse-Dinh

PeerJ· November 2020

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Mechanism of Type IA Topoisomerases.
Tumpa Dasgupta, Shomita Ferdous, Yuk-Ching Tse-Dinh

Molecules· October 2020

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Mechanistic insights from structure of Mycobacterium smegmatis topoisomerase I with ssDNA bound to both N- and C-terminal domains.
Nan Cao, Kemin Tan, Xiaobing Zuo, Thirunavukkarasu Annamalai, Yuk-Ching Tse-Dinh

Nucleic Acids Res· May 2020

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