Publications by authors named "Yuko Nabeshima"

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Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors.
Takeshi Yokoyama, Satoru Fujiwara, Kai Nishikubo, Mineyuki Mizuguchi, Yuko Nabeshima

J Med Chem· January 2025

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Divergent Total Synthesis of Isoflavone Natural Products and Their Potential as Therapeutic Agents for TTR Amyloidosis.
Nguyen Ngoc Thanh Luan, Takuya Okada, Takeshi Yokoyama, Mie Suzuki, Yuko Nabeshima

J Nat Prod· November 2024

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SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD-binding pocket.
Takeshi Yokoyama, Yuki Takayama, Mineyuki Mizuguchi, Yuko Nabeshima, Katsuhiro Kusaka

FEBS Lett· September 2024

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Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis.
Mineyuki Mizuguchi, Takayuki Obita, Seiya Yamada, Yuko Nabeshima

FEBS J· April 2024

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Enzymatic activity of cGAS in the presence of three types of DNAs: limited cGAS stimulation by single-stranded HIV-1 SL2 DNA.
Mineyuki Mizuguchi, Niko Kyan, Suzuka Nishimata, Yuko Nabeshima, Takayuki Obita

Biosci Rep· April 2024

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Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
Mineyuki Mizuguchi, Yusuke Nakagawa, Takeshi Yokoyama, Takuya Okada, Kanako Fujii, Yuko Nabeshima

J Med Chem· April 2024

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Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin.
Takeshi Yokoyama, Mineyuki Mizuguchi, Yuko Nabeshima, Yusuke Nakagawa, Takuya Okada

FEBS J· November 2023

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Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
Takeshi Yokoyama, Katsuhiro Kusaka, Mineyuki Mizuguchi, Yuko Nabeshima, Satoru Fujiwara

J Med Chem· November 2023

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Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity.
Takuya Okada, Kaho Yamabe, Michiko Jo, Yuko Sakajiri, Tomokazu Shibata, Yuko Nabeshima

Bioorg Med Chem Lett· September 2023

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Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.
Mineyuki Mizuguchi, Takeshi Yokoyama, Takuya Okada, Yusuke Nakagawa, Kanako Fujii, Yuko Nabeshima

Bioorg Med Chem· July 2023

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Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin-inducing activity.
Mineyuki Mizuguchi, Takeshi Yokoyama, Takahito Otani, Shiori Kuribara, Yuko Nabeshima

FEBS Lett· June 2023

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Design, synthesis, structure-activity relationship studies, and evaluation of novel GLS1 inhibitors.
Michiko Jo, Keiichi Koizumi, Mizuho Suzuki, Daisuke Kanayama, Yurie Watanabe, Yuko Nabeshima

Bioorg Med Chem Lett· May 2023

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Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis.
Mineyuki Mizuguchi, Yusuke Nakagawa, Kishin Inui, Wakana Katayama, Yurika Sawai, Yuko Nabeshima

J Med Chem· December 2022

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Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
Takeshi Yokoyama, Shiho Fujii, Andreas Ostermann, Tobias E Schrader, Yuko Nabeshima

IUCrJ· September 2022

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Usefulness of the whole-body counter for infants and small children (BABYSCAN) as a risk communication tool after the Fukushima Daiichi nuclear power plant incident.
Masaharu Tsubokura, Yuko Nabeshima, Michio Murakami, Tsuyoshi Nemoto, Toshiyuki Kambe

Proc Jpn Acad Ser B Phys Biol Sci· April 2020

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Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4.
Takeshi Yokoyama, Kazunori Matsumoto, Andreas Ostermann, Tobias E Schrader, Yuko Nabeshima

FEBS J· May 2019

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Allosteric modulation of the binding affinity between PQBP1 and the spliceosomal protein U5-15kD.
Mineyuki Mizuguchi, Takayuki Obita, Asagi Kajiyama, Yuki Kozakai, Tsuyoshi Nakai, Yuko Nabeshima

FEBS Lett· July 2016

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Segmental isotope-labeling of the intrinsically disordered protein PQBP1.
Yuko Nabeshima, Mineyuki Mizuguchi, Asagi Kajiyama, Hitoshi Okazawa

FEBS Lett· December 2014

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Localization of serine racemase and its role in the skin.
Ran Inoue, Yoko Yoshihisa, Yosuke Tojo, Chieko Okamura, Yuzo Yoshida, Yuko Nabeshima

J Invest Dermatol· June 2014

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Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15 kD.
Mineyuki Mizuguchi, Takayuki Obita, Tomohito Serita, Rieko Kojima, Yuko Nabeshima

Nat Commun· April 2014

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Hydrogen-bond network and pH sensitivity in human transthyretin.
Takeshi Yokoyama, Mineyuki Mizuguchi, Yuko Nabeshima, Katsuhiro Kusaka, Taro Yamada

J Synchrotron Radiat· November 2013

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Structural characterization of a trapped folding intermediate of pyrrolidone carboxyl peptidase from a hyperthermophile.
Mineyuki Mizuguchi, Makoto Takeuchi, Shinya Ohki, Yuko Nabeshima, Takahide Kouno

Biochemistry· August 2012

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Quaternary structure, aggregation and cytotoxicity of transthyretin.
Mineyuki Mizuguchi, Takeshi Yokoyama, Yuko Nabeshima, Keiichi Kawano, Ichiro Tanaka

Amyloid· June 2012

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Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin.
Takeshi Yokoyama, Mineyuki Mizuguchi, Yuko Nabeshima, Katsuhiro Kusaka, Taro Yamada

J Struct Biol· February 2012

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The Structure of Physarum polycephalum hemagglutinin I suggests a minimal carbohydrate recognition domain of legume lectin fold.
Takahide Kouno, Nobuhisa Watanabe, Naoki Sakai, Takashi Nakamura, Yuko Nabeshima

J Mol Biol· January 2011

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