Publications by authors named "Yves Matthess"

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Multi-scale classification decodes the complexity of the human E3 ligome.
Arghya Dutta, Alberto Cristiani, Siddhanta V Nikte, Jonathan Eisert, Yves Matthess

Nat Commun· December 2025

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Correction: A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1.
Monika Raab, Yves Matthess, Christopher A Raab, Niklas Gutfreund, Volker Dötsch

Oncogene· August 2023

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Optimized metrics for orthogonal combinatorial CRISPR screens.
Ronay Cetin, Martin Wegner, Leah Luwisch, Sarada Saud, Tatjana Achmedov, Yves Matthess

Sci Rep· May 2023

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A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1.
Monika Raab, Yves Matthess, Christopher A Raab, Niklas Gutfreund, Volker Dötsch

Oncogene· January 2022

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Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome.
Martin Wegner, Valentina Diehl, Verena Bittl, Rahel de Bruyn, Svenja Wiechmann, Yves Matthess

Elife· March 2019

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Synthetic lethality in -amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics.
Sabrina Noack, Monika Raab, Yves Matthess, Mourad Sanhaji, Andrea Krämer

Oncotarget· May 2018

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PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
Monika Raab, Mourad Sanhaji, Yves Matthess, Albrecht Hörlin, Ioana Lorenz

Nat Commun· March 2018

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Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8.
Christina Helmke, Monika Raab, Franz Rödel, Yves Matthess, Thomas Oellerich

Cell Res· August 2016

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Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy.
Franz Rödel, Daniel Martin, Christina Helmke, Panagiotis Balermpas, Emmanouil Fokas, Yves Matthess

Oncotarget· August 2016

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Thoughts on the current assessment of Polo-like kinase inhibitor drug discovery.
Klaus Strebhardt, Sven Becker, Yves Matthess

Expert Opin Drug Discov· January 2015

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Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis.
Yves Matthess, Monika Raab, Rainald Knecht, Sven Becker, Klaus Strebhardt

Mol Oncol· May 2014

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pERK 1/2 inhibit Caspase-8 induced apoptosis in cancer cells by phosphorylating it in a cell cycle specific manner.
Ranadip Mandal, Monika Raab, Yves Matthess, Sven Becker, Rainald Knecht

Mol Oncol· March 2014

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SKAP1 protein PH domain determines RapL membrane localization and Rap1 protein complex formation for T cell receptor (TCR) activation of LFA-1.
Monika Raab, Xin Smith, Yves Matthess, Klaus Strebhardt, Christopher E Rudd

J Biol Chem· August 2011

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Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.
Monika Raab, Sven Kappel, Andrea Krämer, Mourad Sanhaji, Yves Matthess

Nat Commun· July 2011

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Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity.
Yves Matthess, Monika Raab, Mourad Sanhaji, Inna N Lavrik, Klaus Strebhardt

Mol Cell Biol· December 2010

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Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1).
Nina-Naomi Kreis, Katharina Sommer, Mourad Sanhaji, Andrea Krämer, Yves Matthess

Cell Cycle· February 2009

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Silencing of mammalian genes by tetracycline-inducible shRNA expression.
Sven Kappel, Yves Matthess, Manfred Kaufmann, Klaus Strebhardt

Nat Protoc· February 2008

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Tumor inhibition by genomically integrated inducible RNAi-cassettes.
Sven Kappel, Yves Matthess, Brigitte Zimmer, Manfred Kaufmann, Klaus Strebhardt

Nucleic Acids Res· October 2006

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Conditional inhibition of cancer cell proliferation by tetracycline-responsive, H1 promoter-driven silencing of PLK1.
Yves Matthess, Sven Kappel, Birgit Spänkuch, Brigitte Zimmer, Manfred Kaufmann

Oncogene· April 2005

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Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1.
Birgit Spänkuch, Yves Matthess, Rainald Knecht, Brigitte Zimmer, Manfred Kaufmann

J Natl Cancer Inst· June 2004

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