Publications by authors named "Xin Smith"

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LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.
Monika Raab, Yuning Lu, Karsten Kohler, Xin Smith, Klaus Strebhardt

Nat Commun· July 2017

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T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice.
Xin Smith, Alison Taylor, Christopher E Rudd

Immunol Lett· August 2016

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The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.
Xin Smith, Helga Schneider, Karsten Köhler, Hebin Liu, Yuning Lu

Sci Signal· July 2013

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SKAP1 protein PH domain determines RapL membrane localization and Rap1 protein complex formation for T cell receptor (TCR) activation of LFA-1.
Monika Raab, Xin Smith, Yves Matthess, Klaus Strebhardt, Christopher E Rudd

J Biol Chem· August 2011

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T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes.
Monika Raab, Hongyan Wang, Yuning Lu, Xin Smith, Zhonglin Wu

Immunity· April 2010

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Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells.
Helga Schneider, Hongyan Wang, Monika Raab, Elke Valk, Xin Smith

PLoS One· March 2008

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CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization.
Helga Schneider, Xin Smith, Hebin Liu, Georges Bismuth, Christopher E Rudd

Eur J Immunol· January 2008

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OX40 (CD134) blockade inhibits the co-stimulatory cascade and promotes heart allograft survival.
Allison J Curry, Jo Chikwe, Xin G Smith, Ming Cai, Herbert Schwarz

Transplantation· September 2004

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Targeting IL-15 as a therapeutic strategy in organ transplant rejection.
Xin G Smith, Eleanor M Bolton, J Andrew Bradley

Curr Opin Investig Drugs· March 2002

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