Publications by authors named "Zachary D Smith"

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D
Direct genetic transformation bypasses tumor-associated DNA methylation alterations.
Sara Hetzel, Eran Hodis, Elena Torlai Triglia, Alexander Kovacsovics, Kathleen Steinmann, Zachary D Smith

Genome Biol· July 2025

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Evidence of secondary Notch signaling within the rat small intestine.
Eleanor Zagoren, Nicolas Dias, Anderson K Santos, Zachary D Smith, Nadia A Ameen

Development· June 2025

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Computational drug discovery of an inhibitor of APOBEC3B as a treatment for epithelial cancers.
Dominic A Caputa, Quin P Blankenship, Zachary D Smith, Molly M Huebner, Zoe A Vetter

J Biomol Struct Dyn· March 2025

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DNA methylation in mammalian development and disease.
Zachary D Smith, Sara Hetzel, Alexander Meissner

Nat Rev Genet· January 2025

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X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes.
Tim P Hasenbein, Sarah Hoelzl, Zachary D Smith, Chiara Gerhardinger, Marion O C Gonner

Nat Commun· December 2024

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A second wave of Notch signaling diversifies the intestinal secretory lineage.
Eleanor Zagoren, Nicolas Dias, Zachary D Smith, Nadia A Ameen, Kaelyn Sumigray

bioRxiv· July 2024

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Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids.
Adriano Bolondi, Benjamin K Law, Helene Kretzmer, Seher Ipek Gassaloglu, René Buschow, Zachary D Smith

Dev Cell· June 2024

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Autonomous transposons tune their sequences to ensure somatic suppression.
İbrahim Avşar Ilık, Petar Glažar, Kevin Tse, Björn Brändl, David Meierhofer, Zachary D Smith

Nature· February 2024

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Self-patterning of human stem cells into post-implantation lineages.
Monique Pedroza, Seher Ipek Gassaloglu, Nicolas Dias, Liangwen Zhong, Tien-Chi Jason Hou, Zachary D Smith

Nature· October 2023

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DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres.
Aushaq B Malla, Haoming Yu, Delaney Farris, Srilekha Kadimi, TuKiet T Lam, Zachary D Smith

EMBO Rep· August 2023

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DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement.
Aushaq B Malla, Shannon R Rainsford, Zachary D Smith, Bluma J Lesch

Development· May 2023

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Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A Ilik, Zachary D Smith

Nat Cell Biol· April 2023

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Hijacking of transcriptional condensates by endogenous retroviruses.
Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Zachary D Smith

Nat Genet· August 2022

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Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages.
Daniel Andergassen, Zachary D Smith, Helene Kretzmer, John L Rinn, Alexander Meissner

Dev Cell· November 2021

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Smart-RRBS for single-cell methylome and transcriptome analysis.
Hongcang Gu, Ayush T Raman, Xiaoxue Wang, Federico Gaiti, Ronan Chaligne, Zachary D Smith

Nat Protoc· August 2021

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Ulcerative Colitis With Concomitant Serrated Polyposis Syndrome: A Case Report and Literature Review.
Mahmoud M Mansour, Zachary D Smith, Yezaz Ghouri, Veysel Tahan

Cureus· April 2021

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TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers.
Jocelyn Charlton, Eunmi J Jung, Alexandra L Mattei, Nina Bailly, Jing Liao, Zachary D Smith

Nat Genet· August 2020

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Epigenetic regulator function through mouse gastrulation.
Stefanie Grosswendt, Helene Kretzmer, Zachary D Smith, Abhishek Sampath Kumar, Sara Hetzel

Nature· August 2020

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In vivo and deletion elucidates roles for autosomal gene regulation.
Daniel Andergassen, Zachary D Smith, Jordan P Lewandowski, Chiara Gerhardinger, Alexander Meissner

Elife· November 2019

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Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression.
Alexander M Tsankov, Marc H Wadsworth, Veronika Akopian, Jocelyn Charlton, Samuel J Allon, Zachary D Smith

Development· September 2019

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Differential regulation of OCT4 targets facilitates reacquisition of pluripotency.
Sudhir Thakurela, Camille Sindhu, Evgeny Yurkovsky, Christina Riemenschneider, Zachary D Smith

Nat Commun· September 2019

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Molecular recording of mammalian embryogenesis.
Michelle M Chan, Zachary D Smith, Stefanie Grosswendt, Helene Kretzmer, Thomas M Norman

Nature· June 2019

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Targets and genomic constraints of ectopic Dnmt3b expression.
Yingying Zhang, Jocelyn Charlton, Rahul Karnik, Isabel Beerman, Zachary D Smith

Elife· November 2018

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Global delay in nascent strand DNA methylation.
Jocelyn Charlton, Timothy L Downing, Zachary D Smith, Hongcang Gu, Kendell Clement

Nat Struct Mol Biol· April 2018

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Author Correction: Global delay in nascent strand DNA methylation.
Jocelyn Charlton, Timothy L Downing, Zachary D Smith, Hongcang Gu, Kendell Clement

Nat Struct Mol Biol· April 2018

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