Publications by authors named "Ze Guang Han"

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De Novo Detection of Clonal Structure and Evolution in Single-Cell and Spatial Transcriptomes.
Shihao Bai, Xianbin Su, Ziyao Chen, Ze-Guang Han

Int J Mol Sci· November 2025

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Deciphering context-specific gene programs from single-cell and spatial transcriptomics data with DeCEP.
Lin Li, Xianbin Su, Ze-Guang Han

Genome Res· October 2025

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Arid1a Deficiency Drives Aristolochic Acid-Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair.
Lan Wang, Shi-Hao Bai, Shu-Jin Song, Xiao-Li Zhang, Xue-Ying Shang, Ze-Guang Han

Adv Sci (Weinh)· October 2025

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Characterization of the extrinsic and intrinsic signatures and therapeutic vulnerability of small cell lung cancers.
Gui-Zhen Wang, Zheng Wang, Shi-Hao Bai, Yun Tan, Wen-Zhao Zhong, Bin Zhang, Xiang-Wei Zhang, Si-Chong Han, Li Zhang, Chang-Li Wang, Ze-Guang Han, Yuan-Yuan Zhang

Signal Transduct Target Ther· September 2025

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Liquid Guardians: Biomolecular Condensates Shield Heterochromatin Against Cellular Senescence.
Jia Xie, Ze-Guang Han

Bioessays· August 2025

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SCARA5 deficiency inhibits ferroptosis via regulating iron homeostasis and results in sorafenib resistance in hepatocellular carcinoma.
Cong Chen, Lan Wang, Xiao-Fang Cui, Xu-Yang Shang, Shi-Hao Bai, Ze-Guang Han

Cell Signal· May 2025

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Dendritic-cell-targeting virus-like particles as potent mRNA vaccine carriers.
Di Yin, Yiye Zhong, Sikai Ling, Sicong Lu, Xiaoyuan Wang, Hang Yang, Yan Zhang, Ze-Guang Han

Nat Biomed Eng· February 2025

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Heterochromatin formation and remodeling by IRTKS condensates counteract cellular senescence.
Jia Xie, Zhao-Ning Lu, Shi-Hao Bai, Xiao-Fang Cui, He-Yuan Lian, Ze-Guang Han

EMBO J· October 2024

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BAIAP2L1 and BAIAP2L2 differently regulate hair cell stereocilia morphology.
Keji Yan, Haoqing Zhang, Chengli Qu, Yuehui Xi, Ze-Guang Han

FASEB J· August 2024

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Cooperation between IRTKS and deubiquitinase OTUD4 enhances the SETDB1-mediated H3K9 trimethylation that promotes tumor metastasis via suppressing E-cadherin expression.
Xiaofang Cui, Xueying Shang, Jia Xie, Chenyi Xie, Zhanyun Tang, Ze-Guang Han

Cancer Lett· October 2023

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DLK1-directed chimeric antigen receptor T-cell therapy for hepatocellular carcinoma.
Yangyang Zhai, Kunyan He, Liyu Huang, Xuyang Shang, Guangxing Wang, Ze-Guang Han

Liver Int· November 2022

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Accurate tumor clonal structures require single-cell analysis.
Xianbin Su, Shihao Bai, Gangcai Xie, Yi Shi, Linan Zhao, Ze-Guang Han

Ann N Y Acad Sci· November 2022

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Inhibition of Arid1a increases stem/progenitor cell-like properties of liver cancer.
Lan Wang, Chuan-Huai Deng, Qing Luo, Xian-Bin Su, Xue-Ying Shang, Ze-Guang Han

Cancer Lett· October 2022

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BRD4 inhibition induces synthetic lethality in ARID2-deficient hepatocellular carcinoma by increasing DNA damage.
Dan-Dan He, Xue-Ying Shang, Na Wang, Guang-Xing Wang, Kun-Yan He, Ze-Guang Han

Oncogene· March 2022

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Exposure to aristolochic acid I is associated with poor prognosis of liver cancer patients.
Lan Wang, Shi-Hao Bai, Shu-Jin Song, Zhao-Ning Lu, Jian Huang, Ze-Guang Han

Toxicol Res (Camb)· February 2022

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Cinobufagin Is a Selective Anti-Cancer Agent against Tumors with EGFR Amplification and PTEN Deletion.
Kunyan He, Guang-Xing Wang, Li-Nan Zhao, Xiao-Fang Cui, Xian-Bin Su, Shang-Wei Hou, Ze-Guang Han

Front Pharmacol· November 2021

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ARID1A deficiency weakens BRG1-RAD21 interaction that jeopardizes chromatin compactness and drives liver cancer cell metastasis.
Xue-Ying Shang, Yi Shi, Dan-Dan He, Lan Wang, Qing Luo, Ze-Guang Han

Cell Death Dis· October 2021

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Clonal evolution in liver cancer at single-cell and single-variant resolution.
Xianbin Su, Linan Zhao, Yi Shi, Rui Zhang, Qi Long, Bo Han, Shangwei Hou, Ze-Guang Han

J Hematol Oncol· February 2021

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LZP is required for hepatic triacylglycerol transportation through maintaining apolipoprotein B stability.
Jiao-Xiang Wu, Kun-Yan He, Zhuang-Zhuang Zhang, Yu-Lan Qu, Xian-Bin Su, Ze-Guang Han

PLoS Genet· February 2021

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DeepAntigen: a novel method for neoantigen prioritization via 3D genome and deep sparse learning.
Yi Shi, Zehua Guo, Xianbin Su, Luming Meng, Mingxuan Zhang, Xueyin Shang, Chaoyi Zhang, Ze-Guang Han

Bioinformatics· December 2020

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SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70.
He-Wei Jiang, Hai-Nan Zhang, Qing-Feng Meng, Jia Xie, Yang Li, Jing Zhang, Ze-Guang Han

Cell Mol Immunol· September 2020

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Investigating higher-order interactions in single-cell data with scHOT.
Shila Ghazanfar, Yingxin Lin, Xianbin Su, David Ming Lin, Ellis Patrick, Ze-Guang Han

Nat Methods· August 2020

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A novel neoantigen discovery approach based on chromatin high order conformation.
Yi Shi, Mingxuan Zhang, Luming Meng, Xianbin Su, Xueying Shang, Ze-Guang Han

BMC Med Genomics· August 2020

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[A method for reliable detection of genomic point mutations based on single-cell target-sequencing].
Li Nan Zhao, Na Wang, Guo Liang Yang, Xian Bin Su, Ze Guang Han

Yi Chuan· July 2020

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Mutational and transcriptomic landscapes of a rare human prostate basal cell carcinoma.
Xianbin Su, Qi Long, Juanjie Bo, Yi Shi, Li-Nan Zhao, Chao Zhang, Ze-Guang Han

Prostate· May 2020

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