Publications by authors named "Zeki Topcu"

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Molecular biology as a "playground" in the life sciences: Questions on the current status of molecular biology.
Zeki Topcu, Matthis Krischel, Heiner Fangerau

Endeavour· March 2025

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Techno-ethical concerns related to genetic sequencing reports.
Zeki Topcu, Sevil Zencir, Matthis Krischel, Heiner Fangerau

Biosystems· December 2024

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Bimodal Array-Based Fluorescence Sensor and Microfluidic Technology for Protein Fingerprinting and Clinical Diagnosis.
Monica Swetha Bosco, Delphine Naud-Martin, Carlos Gonzalez-Galindo, Marie Auvray, Monica Araya-Farias, Zeki Topcu

ACS Appl Bio Mater· December 2024

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Cucurbit[7]uril Macrocyclic Sensors for Optical Fingerprinting: Predicting Protein Structural Changes to Identifying Disease-Specific Amyloid Assemblies.
Nilanjana Das Saha, Soumen Pradhan, Ranjan Sasmal, Aritra Sarkar, Christian M Berač

J Am Chem Soc· August 2022

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Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase-negative cells.
Sevil Zencir, Meng-Hsun Hsieh, Joel-Sean Hsu, Yavuz Ergun, Guan-Ling Chou, Zeki Topcu

J Cancer Res Clin Oncol· July 2020

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Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes.
Gizem Caliskan, Ikbal C Baris, Ferhan Ayaydin, Melanie J Dobson, Muge Senarisoy, Zeki Topcu

PLoS One· January 2018

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Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives.
Kendra R Vann, Yavuz Ergün, Sevil Zencir, Serkan Oncuoglu, Neil Osheroff, Zeki Topcu

Bioorg Med Chem Lett· April 2016

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Anticancer Properties of Natural Products.
István Zupkó, Walter Jaeger, Zeki Topcu, Chin-Chung Wu

Biomed Res Int· March 2016

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Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.
Kendra R Vann, Güner Ekiz, Sevil Zencir, Erdal Bedir, Zeki Topcu

Chem Res Toxicol· March 2016

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Anticancer and multidrug resistance-reversal effects of solanidine analogs synthetized from pregnadienolone acetate.
István Zupkó, Judit Molnár, Borbála Réthy, Renáta Minorics, Eva Frank, Zeki Topcu

Molecules· February 2014

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Gossypol interferes with both type I and type II topoisomerase activities without generating strand breaks.
Muge Senarisoy, Pakize Canturk, Sevil Zencir, Yusuf Baran, Zeki Topcu

Cell Biochem Biophys· May 2013

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Identification of transcriptional and phosphatase regulators as interaction partners of human ADA3, a component of histone acetyltransferase complexes.
Sevil Zencir, Adam Sike, Melanie J Dobson, Ferhan Ayaydin, Imre Boros, Zeki Topcu

Biochem J· March 2013

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New partner proteins containing novel internal recognition motif for human glutaminase interacting protein (hGIP).
Sevil Zencir, Monimoy Banerjee, Melanie J Dobson, Ferhan Ayaydin, Elfrieda Ayaydin Fodor, Zeki Topcu

Biochem Biophys Res Commun· March 2013

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Recombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity.
Evelina Basenko, Zeki Topcu, Michael J McEachern

Eukaryot Cell· August 2011

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Identification of brain-specific angiogenesis inhibitor 2 as an interaction partner of glutaminase interacting protein.
Sevil Zencir, Mohiuddin Ovee, Melanie J Dobson, Monimoy Banerjee, Zeki Topcu

Biochem Biophys Res Commun· August 2011

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Oxidative stress and apoptosis in relation to exposure to magnetic field.
Mustafa Emre, Salih Cetiner, Sevil Zencir, Isa Unlukurt, Ibrahim Kahraman, Zeki Topcu

Cell Biochem Biophys· March 2011

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Oxidative stress in relation to telomere length maintenance in vascular smooth muscle cells following balloon angioplasty.
Gonen Ozsarlak-Sozer, Zeliha Kerry, Goksel Gokce, Ismail Oran, Zeki Topcu

J Physiol Biochem· March 2011

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Biological activity of 1-aryl-3-phenethylamino-1-propanone hydrochlorides and 3-aroyl-4-aryl-1-phenethyl-4-piperidinols on PC-3 cells and DNA topoisomerase I enzyme.
Ebru Mete, Halise Inci Gul, Pakize Canturk, Zeki Topcu, Bulbul Pandit

Z Naturforsch C J Biosci· March 2011

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The mRNA expression of cytochrome P450 isoforms in human gastric tissue.
Pakize Canturk, Vildan Caner, Nevin Oruc, Ulus Salih Akarca, Emre Tepeli, Zeki Topcu

Hepatogastroenterology· August 2010

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Cytotoxic activity of 4'-hydroxychalcone derivatives against Jurkat cells and their effects on mammalian DNA topoisomerase I.
Halise Inci Gul, Murat Cizmecioglu, Sevil Zencir, Mustafa Gul, Pakize Canturk, Zeki Topcu

J Enzyme Inhib Med Chem· June 2009

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Biological activity of bis-benzimidazole derivatives on DNA topoisomerase I and HeLa, MCF7 and A431 cells.
A Selcen Alpan, Sevil Zencir, István Zupkó, Gunes Coban, Borbála Réthy, Zeki Topcu

J Enzyme Inhib Med Chem· June 2009

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Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays.
Gunes Coban, Sevil Zencir, István Zupkó, Borbála Réthy, H Semih Gunes, Zeki Topcu

Eur J Med Chem· May 2009

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Effect of some bis Mannich bases and corresponding piperidinols on DNA topoisomerase I.
Pakize Canturk, Kaan Kucukoglu, Zeki Topcu, Mustafa Gul, Halise Inci Gul

Arzneimittelforschung· March 2009

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Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype.
Laura H Bechard, Bilge D Butuner, George J Peterson, Will McRae, Zeki Topcu

Mol Cell Biol· February 2009

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Detection of cytochrome P450-2A6, -3A5 and -4B1 with real-time polymerase chain reaction in prostate tissue.
Sevil Zencir, Davut Alptekin, Medih Celiktas, Pakize Canturk, Deniz Colak, Zeki Topcu

Z Naturforsch C J Biosci· December 2008

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