Publications by authors named "Zen Itoh"

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Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride.
Yugo Matsunaga, Takao Tanaka, Koji Yoshinaga, Shigeru Ueki, Yuko Hori, Zen Itoh

J Pharmacol Exp Ther· March 2011

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House musk shrew (Suncus murinus, order: Insectivora) as a new model animal for motilin study.
Chihiro Tsutsui, Kie Kajihara, Takatsugu Yanaka, Ichiro Sakata, Zen Itoh

Peptides· February 2009

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Effects of mitemcinal (GM-611), an orally active erythromycin-derived prokinetic agent, on delayed gastric emptying and postprandial glucose in a new minipig model of diabetes.
Ken-ichi Ozaki, Makoto Monnai, Mitsu Onoma, Hiroyasu Muramatsu, Kenji Yogo, Zen Itoh

J Diabetes Complications· December 2008

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Characterization of multinuclear hepatocytes induced in rats by mitemcinal (GM-611), an erythromycin derivative.
Shuji Hayashi, Etsuko Fujii, Atsuhiko Kato, Kazuya Kimura, Keiji Mizoguchi, Zen Itoh

Toxicol Pathol· October 2008

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Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis.
Mitsu Onoma, Ken-ichi Ozaki, Kenji Yogo, Makoto Monnai, Hiroyasu Muramatsu, Zen Itoh

Clin Exp Pharmacol Physiol· July 2008

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Effects of oral mitemcinal (GM-611), erythromycin, EM-574 and cisapride on gastric emptying in conscious rhesus monkeys.
Kenji Yogo, Mitsu Onoma, Ken-Ichi Ozaki, Masao Koto, Zen Itoh

Dig Dis Sci· April 2008

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Assessment of the carcinogenic potential of mitemcinal (GM-611): increased incidence of malignant lymphoma in a rat carcinogenicity study.
Etsuko Fujii, Kazuya Kimura, Keiji Mizoguchi, Atsuhiko Kato, Hisanori Takanashi, Zen Itoh

Toxicol Appl Pharmacol· April 2008

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Oral mitemcinal (GM-611), an erythromycin-derived prokinetic, accelerates normal and experimentally delayed gastric emptying in conscious dogs.
Mitsu Onoma, Kenji Yogo, Ken-Ichi Ozaki, Kenshi Kamei, Michitaka Akima, Zen Itoh

Clin Exp Pharmacol Physiol· January 2008

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Nonlinear intestinal pharmacokinetics of mitemcinal, the first acid-resistant non-peptide motilin receptor agonist, in rats.
Ryoichi Saitoh, Takashi Miyayama, Tetsuya Mitsui, Yuko Akiba, Atsuko Higashida, Zen Itoh

Xenobiotica· December 2007

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Effects of mitemcinal (GM-611), an acid-resistant nonpeptide motilin receptor agonist, on the gastrointestinal contractile activity in conscious dogs.
Ken-ichi Ozaki, Kenji Yogo, Hirokazu Sudo, Mitsu Onoma, Kenshi Kamei, Zen Itoh

Pharmacology· November 2007

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Effects of motilin and mitemcinal (GM-611) on gastrointestinal contractile activity in rhesus monkeys in vivo and in vitro.
Kenji Yogo, Ken-Ichi Ozaki, Hisanori Takanashi, Masao Koto, Zen Itoh

Dig Dis Sci· November 2007

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Preclinical electrophysiology assays of mitemcinal (GM-611), a novel prokinetic agent derived from erythromycin.
Kazuya Kimura, Mitsuyasu Tabo, Misae Itoh, Keiji Mizoguchi, Atsuhiko Kato, Zen Itoh

J Toxicol Sci· August 2007

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Hemodynamic and electrophysiological effects of mitemcinal (GM-611), a novel prokinetic agent derived from erythromycin in a halothane-anesthetized canine model.
Kazuya Kimura, Mitsuyasu Tabo, Keiji Mizoguchi, Atsuhiko Kato, Masami Suzuki, Zen Itoh

J Toxicol Sci· August 2007

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In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.
Hisanori Takanashi, Kenji Yogo, Ken-ichi Ozaki, Hiroshi Koga, Zen Itoh

Pharmacology· July 2007

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Effects of nitric oxide synthase inhibitor on the digestive system measured by simultaneous monitoring of gastric motility, gastric emptying activity and postprandial pancreaticobiliary secretion in dogs.
Toshiyuki Tanaka, Akiyoshi Mizumoto, Zen Itoh

Exp Anim· July 2005

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Relationship between intraduodenal 5-hydroxytryptamine release and interdigestive contractions in dogs.
Toshiyuki Tanaka, Akiyoshi Mizumoto, Erito Mochiki, Norihiro Haga, Hideki Suzuki, Zen Itoh

J Smooth Muscle Res· June 2004

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Effect of motilin on endogenous release of insulin in conscious dogs in the fed state.
Hideki Suzuki, Hiroyuki Kuwano, Erito Mochiki, Norihiro Haga, Tatuo Shimura, Zen Itoh

Dig Dis Sci· December 2003

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