Publications by authors named "Zoran Rankovic"

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Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics.
Martin Steger, Gisele Nishiguchi, Qiong Wu, Bjoern Schwalb, Bachuki Shashikadze, Zoran Rankovic

Nat Commun· August 2025

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LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia.
Jun J Yang, Gisele Nishiguchi, Satoshi Yoshimura, Marisa Actis, Justin T Seffernick, Zoran Rankovic

bioRxiv· July 2025

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Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target.
Shiekh Tanveer Ahmad, Yiran Li, Jesus Garcia-Lopez, Brian L Gudenas, Jennifer Hadley, Zoran Rankovic

Cancer Cell· June 2025

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HTS Identifies NUP98-KDM5A-PHD3 Domain Ligands with Novel Scaffolds.
Wenwei Lin, P Jake Slavish, Aaron H Phillips, Marlon Trotter, Guangwei Yang, Zoran Rankovic

ACS Med Chem Lett· June 2025

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Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs.
Marisa Actis, Joel Cresser-Brown, Elizabeth A Caine, Martin Steger, Anup Aggarwal, Zoran Rankovic

J Med Chem· February 2025

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Continuous collective analysis of chemical reactions.
Maowei Hu, Lei Yang, Nathaniel Twarog, Jason Ochoada, Yong Li, Zoran Rankovic

Nature· December 2024

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Structure-Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α.
Gisele Nishiguchi, Elizabeth A Caine, Kevin McGowan, Zhe Shi, Anup Aggarwal, Zoran Rankovic

ACS Med Chem Lett· October 2024

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Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length.
Shariq S Ansari, Miriam E Dillard, Yan Zhang, Mary Ashley Austria, Naoko Boatwright, Zoran Rankovic

J Cell Biol· September 2024

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Development of an Orally Bioavailable LCK PROTAC Degrader as a Potential Therapeutic Approach to T-Cell Acute Lymphoblastic Leukemia.
Jamie A Jarusiewicz, Satoshi Yoshimura, Marisa Actis, Yong Li, Xiang Fu, Zoran Rankovic

J Med Chem· July 2024

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Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy.
Marc Zuckermann, Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Zoran Rankovic

Mol Cancer· June 2024

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Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma.
Ahmed Abu-Zaid, Jie Fang, Hongjian Jin, Shivendra Singh, Prahalathan Pichavaram, Zoran Rankovic

Cell Rep Med· March 2024

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A high-throughput quality control method for assessing the serial dilution performance of dose-response plates with acoustic ejection mass spectrometry.
Mary Ashley Rimmer, Nathaniel R Twarog, Yong Li, Anang A Shelat, Zoran Rankovic

SLAS Technol· February 2024

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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Gisele Nishiguchi, Lauren G Mascibroda, Sarah M Young, Elizabeth A Caine, Sherif Abdelhamed, Zoran Rankovic

Nat Commun· January 2024

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Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Sensitive Analysis of Residual Protein Tat Bh1-101 in Lentiviral Vectors for Gene Therapy.
Yan Lu, Chao-Xuan Zhang, Patrick Rodrigues, Lei Yang, Aaron Shafer, Zoran Rankovic

Hum Gene Ther· November 2023

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ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.
Jia Xie, Teneema Kuriakose, Brandon Bianski, Nathaniel Twarog, Evan Savage, Zoran Rankovic

Neuro Oncol· October 2023

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The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia.
Yunchao Chang, Fatemeh Keramatnia, Pankaj S Ghate, Gisele Nishiguchi, Qingsong Gao, Zoran Rankovic

Blood· August 2023

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Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia.
Chun Shik Park, Hiroki Yoshihara, Qingsong Gao, Chunxu Qu, Ilaria Iacobucci, Zoran Rankovic

Cell Rep· July 2023

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Design of Class I/IV Bromodomain-Targeting Degraders for Chromatin Remodeling Complexes.
Huda Zahid, Jeff P Costello, Yao Li, Jennifer R Kimbrough, Marisa Actis, Zoran Rankovic

ACS Chem Biol· June 2023

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From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors.
Mladen Koravovic, Anand Mayasundari, Gordana Tasic, Fatemeh Keramatnia, Timothy R Stachowski, Zoran Rankovic

Eur J Med Chem· May 2023

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Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
Peter J Slavish, Maxime G Cuypers, Mary Ashley Rimmer, Alireza Abdolvahabi, Trushar Jeevan, Zoran Rankovic

Eur J Med Chem· February 2023

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Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design.
Jamie A Jarusiewicz, Satoshi Yoshimura, Anand Mayasundari, Marisa Actis, Anup Aggarwal, Zoran Rankovic

ACS Med Chem Lett· February 2023

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Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo.
Barbara Jonchere, Justin Williams, Frederique Zindy, Jingjing Liu, Sarah Robinson, Zoran Rankovic

Mol Cancer Ther· January 2023

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Small molecule SJ572946 activates BAK to initiate apoptosis.
Giridhar Sekar, Geetika Singh, Xingping Qin, Cristina D Guibao, Brittany Schwam, Zoran Rankovic

iScience· October 2022

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Preclinical evaluation of proteolytic targeting of LCK as a therapeutic approach in T cell acute lymphoblastic leukemia.
Jianzhong Hu, Jamie Jarusiewicz, Guoqing Du, Gisele Nishiguchi, Satoshi Yoshimura, Zoran Rankovic

Sci Transl Med· August 2022

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Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.
Shivendra Singh, Ahmed Abu-Zaid, Hongjian Jin, Jie Fang, Qiong Wu, Zoran Rankovic

Sci Transl Med· July 2022

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