Publications by authors named "Zsofia Digby"

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Anti-Neuroinflammatory and Anti-Inflammatory Effects of the NLRP3 Inhibitor NT-0796 in Subjects with Parkinson's Disease.
Nicholas Clarke, Peter Thornton, Valérie Reader, Nicola Lindsay, Zsofia Digby

Mov Disord· October 2025

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Profile of NT-0527, a brain penetrant NLRP3 Inflammasome inhibitor suitable as an tool compound for neuroinflammatory disorders.
David Harrison, Andy Billinton, Mark G Bock, Nicholas P Clarke, Zsofia Digby

RSC Med Chem· September 2025

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The NLRP3 inhibitor NT-0796 enhances and sustains GLP-1R agonist-mediated weight loss in a murine diet-induced obesity model.
Peter Thornton, Valérie Reader, Zsofia Digby, John Doedens, Nicola Lindsay

Obesity (Silver Spring)· July 2025

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Reversal of High Fat Diet-Induced Obesity, Systemic Inflammation, and Astrogliosis by the NLRP3 Inflammasome Inhibitors NT-0249 and NT-0796.
Peter Thornton, Valérie Reader, Zsofia Digby, Pamela Smolak, Nicola Lindsay

J Pharmacol Exp Ther· February 2024

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A high-resolution mRNA expression time course of embryonic development in zebrafish.
Richard J White, John E Collins, Ian M Sealy, Neha Wali, Christopher M Dooley, Zsofia Digby

Elife· November 2017

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The age of heterozygous mutant parents influences the adult phenotype of their offspring irrespective of genotype in zebrafish.
Catherine M Scahill, Zsofia Digby, Ian M Sealy, Richard J White, Neha Wali

Wellcome Open Res· September 2017

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Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.
Catherine M Scahill, Zsofia Digby, Ian M Sealy, Sonia Wojciechowska, Richard J White

PLoS Genet· August 2017

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