June 2008 PMID 18408140

The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases.

Artemis P Simopoulos

Mentions

149
Peak: 7 in Apr 2019
across 7 sources since Apr 2019

Extended reach

601,432
potential audience

Total likes

2,329

Video views

100,584

Mentions per month

Apr 2019 – Nov 2025

Where it's discussed

  • X / Twitter57 posts
  • News39 articles
  • Facebook36 posts
  • Blogs8 articles
  • YouTube6 videos
  • Reddit2 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The group's discussions show strong consensus on the health importance of maintaining an appropriate omega-6 to omega-3 ratio, with references to scientific studies, dietary advice like hemp seed oil’s optimal ratio, and mentions of chronic diseases such as cardiovascular problems and cancer. The tone is analytical and supportive, emphasizing research findings and practical implications for diet and health.

AgreementStrong agreement

Most discussions express strong agreement with the importance of balancing omega-6/omega-3 ratios, citing studies and expert opinions supporting this view.

InterestHigh interest

The posts demonstrate high interest, frequently mentioning specific ratios, health conditions, and dietary sources, reflecting deep engagement.

EngagementModerate engagement

Participants reference research, share dietary advice, and discuss mechanisms like endocannabinoids, indicating active and thoughtful involvement.

ImpactHigh impact

The widespread sharing of studies and calls for dietary change suggest these discussions could influence health awareness and dietary habits, indicating high potential impact.

Abstract in brief

  • Human evolution favored a diet with a balanced omega6 to omega3 ratio of about 1:1, but Western diets today have a much higher ratio, often between 15:1 and 16:1, which is linked to increased risk of chronic diseases.
  • Excessive omega6 fatty acids and a high omega6 to omega3 ratio promote diseases like cardiovascular problems, cancer, and inflammation, while increasing omega3 intake and lowering the ratio can help prevent or mitigate these conditions.
  • The ideal omega6 to omega3 ratio for disease prevention varies depending on the specific illness, but generally, a lower ratio (around 4:1) appears to significantly reduce mortality and disease activity in conditions like heart disease, cancer, rheumatoid arthritis, and asthma.]

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer. Unfortunately, the Western diet promotes a high ratio. https://t.co/KZVgfFBeMu

Apr 24, 2019 · 55 likes · 9 shares · 291,091 followers View post →
Dr Dawn Arda
@DawnArda · X

Chronic #inflammation is linked to several long term illnesses such as cancer, heart disease and Alzheimer’s. One way to influence inflammation in the body is the ratio of #omega6 (pro-inflammatory) to #omega3 fats (anti-inflammatory) in the diet. https://t.co/flrFnLFwUL https://t.co/jhHMm3XcO3

Dec 5, 2020 · 8 likes · 8,141 followers View post →
Jacob Edward
@JacobEdwardInc · X

Studies have also demonstrated that a lower omega-6 to omega-3 ratio resulted in favorable outcomes compared to those with higher ratios in the following conditions: -Colorectal cancer -Breast cancer -Asthma -Rheumatoid arthritis… https://t.co/g0w66jGRlf

Feb 7, 2023 · 7 likes · 2 shares · 20,624 followers View post →
Reiner 
@erlesen · X

Human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids of ~ 1 whereas in Western diets the ratio is 15/1-16.7/1. Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty acids https://t.co/cQrBGG7J3t 2008 Apr

Jun 15, 2024 · 7 likes · 3 shares · 7,848 followers View post →
Tom Speed
@TomSpeed420 · X

The correct ratio of Omega 3:6 fats are crucial to preventing many disease states. It varies from one disease to another, but a ratio of around 1:4 (O3:6) is best overall, and that can be found in? Yup, Hemp Seed Oil.

Mar 6, 2024 · 7 likes · 2 shares · 2,040 followers View post →
Joshua Durham D.O.
@JoshuaDurhamDO · X

Normalize that omega 6:3 ratio back to an evolutionary level of <4:1 and see what happens. We are not all here to be sick! https://t.co/6j31Dore3m

Jan 6, 2024 · 6 likes · 2 shares · 582 followers View post →

All mentions

Tom Speed
@TomSpeed420 · X

@NTFabiano Eggs have more Omega 3, human diets are generally rich in Omega 6. O6/O3 imbalances actually promote many diease states. https://t.co/QiraDaMe3H Alzheimer's also involves ECS dysfunction, and Anandamide(AEA) deficiencies. O6/O3 are precursors to AEA too! https://t.co/BpERPdgZAf https://t.co/mndU9V5dUs

Jul 30, 2025 · 2,040 followers View post →
JonDel
@jondel747 · X

@GladstoneB81859 any validity in this study? https://t.co/QZDjz8f5GR

Jun 25, 2025 · 6 followers View post →
Darius Sharpe
@MurseDarius · X

@jondel747 @NutritionMadeS3 Artemis Simopoulos has done the best work on this subject https://t.co/IlOhmOfUH1

Jun 25, 2025 · 1 like · 355 followers View post →
Tom Speed
@TomSpeed420 · X

@dikaabaharuddin @dopamineWill @NTFabiano @Dr_Dale0 In fact, an incorrect ratio of Omega 3/6 fats is known to promote many commmon disease states. https://t.co/QiraDaLGe9 https://t.co/hil48Oc2JA

May 12, 2025 · 2 likes · 2,040 followers View post →
Tom Speed
@TomSpeed420 · X

@JoeLoganTalley @bugscotti @ramspacek @ClarkeMicah Deficiencies seem to be a common cause. https://t.co/BpERPdgrKH And may even be linked to the excess Omega6:Omega3 (endocannabinoid precursors) ratio found in western diets. 1:1 = good, many diets upto 17:1 ! https://t.co/QiraDaLGe9 Hemp Seed Oil = perfect. Around 3-4:1.

May 6, 2025 · 2,040 followers View post →
Raun Hargrove
@neotek421 · X

@hubermanlab These folks have some good cites: https://t.co/6JIO2hK1yo Had to pick through some, but this guy: https://t.co/Pp1zUe4g7T and https://t.co/oJRbnv5Hs3 Thank you for doing what you do!

Dec 10, 2024 · 59 followers View post →
Greg Mushen
@gregmushen · X

@LiesByLyingLiar It’s usually expressed in 6:3. So about three omega 6’s to every one omega three. There have been a lot of papers on it. More people are starting to focus on the omega index instead. https://t.co/QSn2xbryz2 https://t.co/Ba35XSeaLR

Nov 25, 2024 · 1 like · 28,504 followers View post →
Kae
@kaethebae321 · X

@SwipeWright Here’s a second study. https://t.co/anLGrwGPAk

Nov 19, 2024 · 130 followers View post →
Danny
@gainoholic · X

@SwipeWright https://t.co/YSkaeCjKSc https://t.co/ISC6Ze9rPH

Nov 18, 2024 · 18 followers View post →
son_of_apollo
@apollo_21c · X

@SwipeWright https://t.co/PavZgSfqWs

Nov 18, 2024 · 56 followers View post →
Charlotte°❀⋆
@charlottexou · X

Studies: seed oils https://t.co/gEKsrxAYkr https://t.co/av77BzxINg https://t.co/cTjdLNMzDY

Aug 2, 2024 · 1 like · 11,331 followers View post →
Reiner 
@erlesen · X

RT @erlesen: Human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids of ~ 1 whereas in Western diets the ra…

Jun 18, 2024 · 3 shares · 7,848 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @erlesen: Human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids of ~ 1 whereas in Western diets the ra…

Jun 17, 2024 · 3 shares · 767 followers View post →
_MCRicardo_
@_MCRicardo_ · X

RT @erlesen: Human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids of ~ 1 whereas in Western diets the ra…

Jun 16, 2024 · 3 shares · 1,966 followers View post →
Reiner
@erlangen.bsky.social · Bluesky

Human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids of ~ 1 whereas in Western diets the ratio is 15/1-16.7/1. Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty acids pubmed.ncbi.nlm.nih.gov/18408140/ 2008 Apr

Jun 15, 2024 View post →
Reiner 
@erlesen · X

Human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids of ~ 1 whereas in Western diets the ratio is 15/1-16.7/1. Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty acids https://t.co/cQrBGG7J3t 2008 Apr

Jun 15, 2024 · 7 likes · 3 shares · 7,848 followers View post →
Tom Speed
@TomSpeed420 · X

@fpc @CLEARdrugpolicy Superior diets. Likely good sources of Omega fats. Omega 3:6 fats are the precurors/building blocks for endocannabinoids, and studies show having O3:6 in ratios other than around 1:3 tends to promote disease states! FYI, Hemp SEED oil = 1:3, PERFECT! https://t.co/QiraDaLGe9 https://t.co/p19Cpw6JCQ

Jun 14, 2024 · 2,040 followers View post →
StandingTall
@hapyhusbandwife · X

@SamanthaRedeemd Now I just shows the evidence, no hate here. The doses make the poison https://t.co/Y6DmkmOjaP, https://t.co/IlWvbBwYuR, https://t.co/eRuYWXKpQR.

Apr 14, 2024 · 1 like · 366 followers View post →
Legalise Cannabis Campaign Scotland
@Legalisecanabo · X

RT @TomSpeed420: The correct ratio of Omega 3:6 fats are crucial to preventing many disease states. It varies from one disease to another,…

Mar 7, 2024 · 2 shares · 3,004 followers View post →
Kansans For Hemp
@Kansans4Hemp · X

RT @TomSpeed420: The correct ratio of Omega 3:6 fats are crucial to preventing many disease states. It varies from one disease to another,…

Mar 6, 2024 · 2 shares · 2,787 followers View post →
Tom Speed
@TomSpeed420 · X

The correct ratio of Omega 3:6 fats are crucial to preventing many disease states. It varies from one disease to another, but a ratio of around 1:4 (O3:6) is best overall, and that can be found in? Yup, Hemp Seed Oil.

Mar 6, 2024 · 7 likes · 2 shares · 2,040 followers View post →
David Vio
@DavidVio2 · X

@MountainVisions @martykendall2 Harris is wrong The importance of the n-6/n-3 fatty acid ratio in CVD and other chronic diseases "ratio of 2.5/1 reduced rectal cell proliferation in patients with colorectal cancer, whereas a ratio of 4/1 with the same amount of n-3 PUFA had no effect" https://t.co/zY5oHPb93j

Feb 19, 2024 · 243 followers View post →
Diane Langdon
@diane_idaho · X

@CaryKelly11 Omega 6:3 ratio is driven higher with consumption of seed oils and nuts which are higher in Omega 6. Link to article below notes that a “ratio of 4/1 was associated with a 70% decrease in total mortality.” https://t.co/G3ULnMNUeU

Feb 17, 2024 · 530 followers View post →
Thomas Günzler
@TGnzler · X

RT @JoshuaDurhamDO: Normalize that omega 6:3 ratio back to an evolutionary level of <4:1 and see what happens. We are not all here to be si…

Jan 22, 2024 · 2 shares · 95 followers View post →
Diane Langdon
@diane_idaho · X

RT @JoshuaDurhamDO: Normalize that omega 6:3 ratio back to an evolutionary level of <4:1 and see what happens. We are not all here to be si…

Jan 6, 2024 · 2 shares · 530 followers View post →
Joshua Durham D.O.
@JoshuaDurhamDO · X

Normalize that omega 6:3 ratio back to an evolutionary level of <4:1 and see what happens. We are not all here to be sick! https://t.co/6j31Dore3m

Jan 6, 2024 · 6 likes · 2 shares · 582 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/sRqoMPQ38u La importancia de la relación de ácidos grasos omega-6 / omega-3 en enfermedades cardiovasculares y otras enfermedades crónicas

Oct 30, 2023 · 8,042 followers View post →
Johan Slåttavik
@JohanSlattavik · X

@NisselueP @segrov Her er noen kilder: https://t.co/4Q0waQJE3Y https://t.co/ACCGc7Xbhu https://t.co/x5ticC6T5n https://t.co/Op77m6tCgk https://t.co/8Cjod8pXyu

Jul 29, 2023 · 1 like · 1,503 followers View post →
Dr Shiivv
@shiv_twitts · X

https://t.co/JCuDQtJ3de

Jun 26, 2023 · 1 like · 1,523 followers View post →
Jeetu Gurdasani
@Jeetu_2486 · X

RT @JacobEdwardInc: Studies have also demonstrated that a lower omega-6 to omega-3 ratio resulted in favorable outcomes compared to those w…

Feb 7, 2023 · 2 shares · 148 followers View post →
Nashe Richmond
@kingfisher6919 · X

RT @JacobEdwardInc: Studies have also demonstrated that a lower omega-6 to omega-3 ratio resulted in favorable outcomes compared to those w…

Feb 7, 2023 · 2 shares · 1,115 followers View post →
Jacob Edward
@JacobEdwardInc · X

Studies have also demonstrated that a lower omega-6 to omega-3 ratio resulted in favorable outcomes compared to those with higher ratios in the following conditions: -Colorectal cancer -Breast cancer -Asthma -Rheumatoid arthritis… https://t.co/g0w66jGRlf

Feb 7, 2023 · 7 likes · 2 shares · 20,624 followers View post →
Danitsa Rodrigues MD, MSc,PhD
@psiquidanitsa · X

dietas ocidentais tem razão ômega6/ômega3 alta o q se associa a maior risco de doenças crônicas não transmissíveis https://t.co/jPbLx7O10y

Aug 2, 2022 · 1 like · 763 followers View post →
Ty Beal
@TyBealPhD · X

@kevinnbass Simolpoulos seem to disagree still, just 6 months prior to this publication. https://t.co/6mGUISwFJV

Nov 1, 2021 · 12,577 followers View post →
Ty Beal
@TyRBeal · X

@kevinnbass Simolpoulos seem to disagree still, just 6 months prior to this publication. https://t.co/6mGUISwFJV

Nov 1, 2021 · 12,343 followers View post →
Ty Beal
@TyRBeal · X

And a somewhat more recent paper on the subject. https://t.co/6mGUISwFJV

Nov 1, 2021 · 5 likes · 12,343 followers View post →
Ty Beal
@TyBealPhD · X

And a somewhat more recent paper on the subject. https://t.co/6mGUISwFJV

Nov 1, 2021 · 5 likes · 12,577 followers View post →
Jayson Merlino ©
@mindcrook · X

RT @DiscoStew66: https://t.co/hzvq9oyq85

May 9, 2021 · 1 share · 286 followers View post →
Dr Dawn Arda
@DawnArda · X

Chronic #inflammation is linked to several long term illnesses such as cancer, heart disease and Alzheimer’s. One way to influence inflammation in the body is the ratio of #omega6 (pro-inflammatory) to #omega3 fats (anti-inflammatory) in the diet. https://t.co/flrFnLFwUL https://t.co/jhHMm3XcO3

Dec 5, 2020 · 8 likes · 8,141 followers View post →
MacroFour
@MacroFour · X

@Tom_Babington1 @ScepticalDoctor Just to finish this off, here is a paper cited 476 times discussing the relevance to health of the omega6:omega3 ratio. https://t.co/d1XP4H777N It wouldn't be the 1st time to be blocked for demonstrating someone was intellectually dishonest & them running away to avoid issues. https://t.co/0SkUeO5eQ6

Oct 6, 2020 · 6,073 followers View post →
Mike Roberto
@MicroBerto · X

@neighborchick @ChristianTams @TerryExSci @patentbobm @ChristianAssad 4. "The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases" https://t.co/Mt74fH6GSN

Aug 7, 2020 · 4,193 followers View post →
Jivo Wellness
@jivo_wellness · X

Good Ratio of Omega-6 & Omega-3 fatty acid are beneficial in in cardiovascular disease and other chronic diseases. SOURCE: https://t.co/398SKf00AJ #HealthyCanola #JivoWorldHealthyWorld #StayHomeStaySafe #FreeHomeDelivery #Jivo #COD https://t.co/3u38ZkQSll

Aug 7, 2020 · 3 likes · 867 followers View post →
Melchior Meijer
@PolderPaleo · X

@ScepticalDoctor https://t.co/w8ydZIMKPl

Jul 4, 2020 · 1 like · 5,180 followers View post →
Nick Eggleton
@NickEggleton · X

@TheAlanAragon Ironic that you’re ‘merely responding’ to my mere response. ;-) Yes. I’m with Rob. I asked rather than presumed though. So I’ll see your 2 & raise you one. https://t.co/ry6Nack9HV https://t.co/tMNAPturYk https://t.co/vVSmORlxc3 P&G will welcome your crisco fandom though.

Jun 7, 2020 · 2,221 followers View post →
Nick Eggleton
@NickEggleton · X

@The_Nutrivore @TerryExSci @FoodFirst_Ty https://t.co/ry6Nack9HV https://t.co/9yfkgMD3e5 https://t.co/tMNAPturYk

Jun 4, 2020 · 2,221 followers View post →
Brain Armor
@Brain_Armor · X

@OrganicLiveFood Yes! Lowering the Omega6: Omega3 ratio to 4:1 is associated with lower inflammation and a 70% decrease in total mortality! https://t.co/Nrm9GmpxBr

May 14, 2020 · 1,287 followers View post →
Health Research
@GuiltFreeTips · X

The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. - #PubMed - @NCBI https://t.co/dsdv2RCxmE

Jul 27, 2019 · 2,270 followers View post →
BioNews Central
@bionewscentral · X

Massachusetts General Hospital investigators used novel transgenic mouse models to obtain new evidence supporting the importance of the omega-6/omega-3 fatty acid ratio in #ChronicDisease #prevention. #PolyunsaturatedFattyAcids #PUFA #FattyAcidBalance https://t.co/SFgdwnek8f

Jul 26, 2019 · 222 followers View post →
Mohammad Qudah
@msqud1 · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Jul 5, 2019 · 9 shares · 126 followers View post →
Davor Stamenovic
@Thoraxchirurg_ · X

@Mangan150 It seems as if you might have been wrong regarding the rape seeds! According to Dr.Simopoulos, it should be containing ALA, the "parent" omega 3 FA. Btw. flax, chia, perilla and walnuts should be containing ALA as well https://t.co/mIthE5RfYB

Jun 23, 2019 · 394 followers View post →
Linda Galliher
@LindaGalliher · X

@KenDBerryMD @ChristianAssad @Travis_Statham The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. - PubMed - NCBI https://t.co/VwWxoAwN46

Jun 15, 2019 · 841 followers View post →
Dr Sam Pappas
@DrSamPappas · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Apr 25, 2019 · 9 shares · 2,089 followers View post →
K.R.L.Rao Chilukuri
@letsgrowmoney · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Apr 25, 2019 · 9 shares · 596 followers View post →
Özüm Şenoğlu
@ozumsenoglu · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Apr 24, 2019 · 9 shares · 117 followers View post →
post scriptum
@psipika · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Apr 24, 2019 · 9 shares · 391 followers View post →
MF
@MFraylick · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Apr 24, 2019 · 9 shares · 668 followers View post →
DiscoStew
@DiscoStew66 · X

RT @Mangan150: A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer.…

Apr 24, 2019 · 9 shares · 10,586 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

A lower ratio of omega-6/omega-3 fatty acids reduces the risk of many chronic diseases, including heart disease and cancer. Unfortunately, the Western diet promotes a high ratio. https://t.co/KZVgfFBeMu

Apr 24, 2019 · 55 likes · 9 shares · 291,091 followers View post →