Mol Neurobiol October 2011 PMID 21279554

Evolutionary aspects of diet: the omega-6/omega-3 ratio and the brain.

Artemis P Simopoulos

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Mentions

27
Peak: 1 in Feb 2021
across 5 sources since Feb 2021

Extended reach

28,846
potential audience

Total likes

877

Video views

13,193

Mentions per month

Feb 2021 – Apr 2025

Where it's discussed

  • News12 articles
  • X / Twitter5 posts
  • Facebook4 posts
  • YouTube3 videos
  • Blogs3 articles

AI synopsis

What people are saying

Several posts discuss the metabolic and neurological significance of the omega-6/omega-3 ratio, such as references to its role in depression and disease, with language indicating curiosity and support, like 'evolutionary aspects' and 'dietary implications,' which reflect a moderate but meaningful engagement and recognition of impact.

AgreementModerate agreement

Most discussions acknowledge the importance of the omega-6/omega-3 ratio based on the article, with some emphasizing its relevance to health and depression.

InterestModerate interest

Participants express moderate interest through comments about dietary implications and evolutionary perspectives.

EngagementModerate engagement

Posts show some depth by referencing specific mechanisms, like inflammation and brain development, but overall engagement remains moderate.

ImpactModerate impact

The discussions generally recognize the potential health impact of balancing fatty acids, illustrating a collective view that the research could influence dietary strategies.

Abstract in brief

  • Human ancestors evolved on a diet with an omega6 to omega3 fatty acid ratio of about 11:1, but modern Western diets have a much higher ratio of 10-20:1, leading to omega3 deficiency.
  • Omega6 and omega3 fatty acids are essential for cell membranes and are not interchangeable in the human body; DHA is particularly crucial for brain and retina development, especially in premature infants.
  • Maintaining a proper balance of omega6 and omega3 fatty acids is important for overall health, brain function, and emotional regulation, with emerging evidence linking omega3s like EPA and DHA to reduced hostility, violence, and substance abuse issues.]

Top posts

Most liked on X and Bluesky
Thomas P Seager, PhD
@seagertp · X

@TheRealCVDW @Mangan150 "imbalance in the omega-6/omega-3 PUFA ratio in major depression may be related to the increased production of proinflammatory cytokines" "The fatty acids are available to composition of cell membranes depend on diet and endogenous metabolism of LA & ALA" https://t.co/QGyDHHlUpH

Nov 25, 2022 · 4 likes · 13,048 followers View post →
Jane Doe
@J__Doh · X

@ejustin46 Thank you. Only take omega 3, we get enough of the others in light of evolution https://t.co/TOtG1r80On

Apr 21, 2024 · 1 like · 742 followers View post →
Victor Robert
@viktorobert · X

@SwipeWright Simopoulos AP. Evolutionary aspects of diet: the omega-6/omega-3 ratio and the brain. Mol Neurobiol 2011;44:203–15.

Nov 18, 2024 · 1,317 followers View post →
Diane Langdon
@diane_idaho · X

@nob12deficiency I know your focus is B12 deficiency but … An Omega 6:3 ratio >4:1 is driver of metabolic disease. In 2011, urban India had 38-50:1 ratio. Evolutionary Aspects of Diet: The Omega-6/Omega-3 Ratio and the Brain, October 2011, Molecular Neurobiology 44(2):203-15 https://t.co/IEMngPAWvY

Jan 20, 2024 · 534 followers View post →

All mentions

roei zucker
@roeizucker · X

@MikeRouah @BatyaCohen1 איך אתה יכול להוכיח שהיחס בין אומגה 6 לאומגה 3 לא חשוב? אי אפשר להוכיח שזה לא חשוב בלי לעשות ניסויים על בני אדם, ממש כמו עם MSG. בפועל אם אתה רוצה ללכת בדרך ה"טבע", בטבע בני אדם צרכו יחס של 1/1: https://t.co/F0AiWMpzb4. צריכה של דגים ושמן צמחי ביחד תיתן יחס כזה.

Apr 4, 2025 · 14 followers View post →
Victor Robert
@viktorobert · X

@SwipeWright Simopoulos AP. Evolutionary aspects of diet: the omega-6/omega-3 ratio and the brain. Mol Neurobiol 2011;44:203–15.

Nov 18, 2024 · 1,317 followers View post →
Jane Doe
@J__Doh · X

@ejustin46 Thank you. Only take omega 3, we get enough of the others in light of evolution https://t.co/TOtG1r80On

Apr 21, 2024 · 1 like · 742 followers View post →
Diane Langdon
@diane_idaho · X

@nob12deficiency I know your focus is B12 deficiency but … An Omega 6:3 ratio >4:1 is driver of metabolic disease. In 2011, urban India had 38-50:1 ratio. Evolutionary Aspects of Diet: The Omega-6/Omega-3 Ratio and the Brain, October 2011, Molecular Neurobiology 44(2):203-15 https://t.co/IEMngPAWvY

Jan 20, 2024 · 534 followers View post →
Thomas P Seager, PhD
@seagertp · X

@TheRealCVDW @Mangan150 "imbalance in the omega-6/omega-3 PUFA ratio in major depression may be related to the increased production of proinflammatory cytokines" "The fatty acids are available to composition of cell membranes depend on diet and endogenous metabolism of LA & ALA" https://t.co/QGyDHHlUpH

Nov 25, 2022 · 4 likes · 13,048 followers View post →