J Proteome Res August 2018 PMID 29945450

Transformative Opportunities for Single-Cell Proteomics.

Harrison Specht, Nikolai Slavov

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Mentions

151

Peak: 30 in Jun 2019

across 5 sources since Dec 2017

Extended reach

1,059,663

potential audience

Total likes

676

Video views

27,665

Mentions per month

Dec 2017 – Oct 2025

Where it's discussed

X / Twitter130 posts
YouTube9 videos
Blogs8 articles
Facebook2 posts
News2 articles

AI synopsis

What people are saying

Participants frequently praise the technological advancements in single-cell proteomics, such as the SCoPE2 protocol and high-throughput methods, with words like 'exciting,' 'major gains,' and 'transformative,' which reflect both enthusiasm and recognition of its potential. The tone and detailed references suggest a community deeply engaged and optimistic about the scientific impact of these innovations.

AgreementModerate agreement

Most participants express strong support and enthusiasm for the developments in single-cell proteomics, emphasizing its transformative potential and technological progress.

InterestHigh interest

Discussions show high interest, with many references to advances, future opportunities, and ongoing research efforts, indicating active engagement in the field.

EngagementHigh engagement

Posts include detailed technical insights, references to conferences, figures, and methodologies, demonstrating deep involvement and analysis.

ImpactHigh impact

The conversations highlight a significant impact on scientific research, funding, and methodological evolution, showing this field's potential to revolutionize biology.

Abstract in brief

Single-cell proteomics using mass spectrometry (MS) has the potential to revolutionize medical research by allowing precise measurement of thousands of proteins in individual cells, which is currently limited.
Advances in technology are focused on significantly improving the sensitivity and speed of MS, enabling the analysis of many cells more efficiently and accurately.
These developments will lead to breakthroughs in diagnosing diseases, understanding biological processes, and developing targeted treatments, ultimately transforming medicine and biological research.]

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All mentions

Advancements in Single-Cell Proteomics Using Mass Spectrometry

Nikolai Slavov · Dec 2, 2017 9,014 views

Advancements in Single-Cell Proteomics and Benchmark Standards

In this presentation, Nikolai Slavov discusses miniaturizing and automating sample preparation for single-cell proteomics. Emphasizing key challenges and solutions, he presents single-cell protein measurements and…

Nikolai Slavov · Jun 20, 2019 4,970 views

Designing Effective Single-Cell Proteomics Experiments for Accurate Data

Nikolai Slavov · Jun 20, 2019 3,695 views

Advancements in Single-Cell Proteomics Using SCoPE2 Technology

This presentation by Nikolai Slavov introduces SCoPE2, a novel technology that enhances single-cell proteomics analysis. It focuses on quantifying over 2000 proteins in individual monocytes and macrophages, highlighting…

Nikolai Slavov · Jun 20, 2019 2,780 views

Advances in Single-Cell Proteomics Sample Preparation for Mass Spectrometry

Presentation by Ed Emmott discussing the SCoPE2 pipeline for processing single-cell samples, emphasizing automation and high throughput, essential for accurate proteomics analysis in small samples.

Nikolai Slavov · Jun 20, 2019 2,715 views

Advancements and Challenges in Single-Cell Proteomics Using Mass Spectrometry

Nikolai Slavov discusses progress and standards in single-cell proteomics, highlighting how mass spectrometry can revolutionize medical research by enabling precise measurement of proteins in individual cells. These…

Nikolai Slavov · Aug 14, 2018 2,123 views

Optimizing Single-Cell Proteomics with LC-MS/MS Techniques

Gray Huffman discusses experimental and computational methods for optimizing single-cell mass spec analysis, focusing on setting optimal parameters for improved sensitivity and accuracy in proteomics research.

Nikolai Slavov · Jun 20, 2019 1,920 views

Exploring Trends in Single-Cell Proteomics at SCP2024

This panel discussion at SCP2024 examines major trends and opportunities in single-cell proteomics. Advances in technology allow for detailed analysis at the single-cell level, crucial for breakthroughs in cancer…

Nikolai Slavov · Jul 19, 2024 396 views

Advances in Single-Cell Proteomics Techniques and Challenges

Panel discussion at SCP2025 on major trends and opportunities in single-cell proteomics, focusing on emerging single-molecule and mass spectrometry methods to analyze the proteome's complexity.

Nikolai Slavov · Jun 26, 2025 54 views

Parallel Squared Technology Institute (PTI)

@ParallelSqTech · X

RT @slavov_n: The counting statistics for single-cell MS support accurate estimates of protein abundance in single cells, which is essentia…

Oct 4, 2025 · 1 share · 839 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

The counting statistics for single-cell MS support accurate estimates of protein abundance in single cells, which is essential for quantitative analysis. Further, measuring and modeling protein degradation is key to biological interpretations. https://t.co/peylTx1mN6

Oct 4, 2025 · 7 likes · 1 share · 20,844 followers View post →

Single-Cell Proteomics Conference

@SCP_meeting · X

RT @slavov_n: This @SCP_meeting presentation discusses more details of such comparisons, especially in regard to using the "black" scatter…

Jan 4, 2025 · 1 share · 2,196 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

This @SCP_meeting presentation discusses more details of such comparisons, especially in regard to using the "black" scatter plots for QC. . https://t.co/y2DdXQSJDe

Jan 3, 2025 · 4 likes · 1 share · 19,787 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

Simpson’s Paradox is one of the confounding relationships that single-cell analysis can help reveal: https://t.co/peylTx0OXy https://t.co/KpumGOEJ56

Oct 18, 2024 · 8 likes · 19,970 followers View post →

Jonathan Hoyne

@HoyneJonat82207 · X

RT @SCP_meeting: Our panel discussion from #SCP2024 is on YouTube: Major trends and opportunities in single-cell proteomics https://t.co/…

Jul 19, 2024 · 1 share · 16 followers View post →

Single-Cell Proteomics Conference

@SCP_meeting · X

Our panel discussion from #SCP2024 is on YouTube: Major trends and opportunities in single-cell proteomics https://t.co/fj4YmR0uy5

Jul 19, 2024 · 2 likes · 1 share · 2,196 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

Recently, a funder told me that our 2018 @JProteomeRes perspective influenced the funding of a research proposal that I had submitted years ago. Perspectives may catalyze intellectual progress and even influence practical matters. https://t.co/peylTx0OXy

Feb 16, 2024 · 8 likes · 19,970 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

RT @Convergent_FROs: We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking t…

Dec 6, 2023 · 6 shares · 19,970 followers View post →

Ben Reinhardt

@Ben_Reinhardt · X

RT @Convergent_FROs: We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking t…

Dec 6, 2023 · 6 shares · 11,514 followers View post →

Parallel Squared Technology Institute (PTI)

@ParallelSqTech · X

RT @Convergent_FROs: We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking t…

Dec 6, 2023 · 6 shares · 807 followers View post →

Kumar Garg

@KumarAGarg · X

RT @Convergent_FROs: We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking t…

Dec 6, 2023 · 6 shares · 38,088 followers View post →

Ben Andrew

@benwandrew · X

RT @Convergent_FROs: We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking t…

Dec 6, 2023 · 6 shares · 202 followers View post →

Anastasia Gamick

@AGamick · X

RT @Convergent_FROs: We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking t…

Dec 6, 2023 · 6 shares · 1,809 followers View post →

Convergent Research

@Convergent_FROs · X

We read that 2018 roadmap paper (in 2020) and thought: "let's FRO" https://t.co/UXcVv52D7U More such forward-looking technical roadmaps from the research community would be appreciated. https://t.co/Bis5zxpruN

Dec 6, 2023 · 15 likes · 6 shares · 3,807 followers View post →

Slavov Laboratory

@slavovLab · X

RT @slavov_n: Looking back at this perspective from 2018, technology developed along expected trends, untapped by creative solutions and so…

Aug 12, 2023 · 1 share · 2,828 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

Looking back at this perspective from 2018, technology developed along expected trends, untapped by creative solutions and solid engineering. More surprises came from biological discoveries enabled by the new technologies. https://t.co/peylTx1mN6

Aug 12, 2023 · 6 likes · 1 share · 19,970 followers View post →

Nguyen Nguyen

@nhunguyen9426 · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 26, 2023 · 11 shares · 48 followers View post →

Bit Civilization

@bitcivilization · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 26, 2023 · 11 shares · 22 followers View post →

Kathryn M. Ross

@DrKathrynRoss · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 1,602 followers View post →

Joy A. Franco, PhD

@engineering_joy · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 2,983 followers View post →

Dr. Darren Abbey

@thebiologistisn · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 8,518 followers View post →

the_kinky_parrot

@KinkyParrot · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 60 followers View post →

司徒

@szetoinsitu · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 1,824 followers View post →

Mac Shine

@jmacshine · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 3,962 followers View post →

Ana B Villaseñor-Altamirano

@AnaBetty2304 · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 848 followers View post →

Burçin Acar

@neseruzgari · X

RT @slavov_n: Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 11 shares · 776 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

Data always have "patterns", which reminds me of this quote. https://t.co/eUxC1vYT2w https://t.co/R8ZnLDJDz1

Jul 25, 2023 · 180 likes · 11 shares · 19,787 followers View post →

Slavov Laboratory

@slavovLab · X

RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…

Jul 22, 2023 · 4 shares · 2,828 followers View post →

audrey combes

@Audrey_Combes · X

RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…

Jul 22, 2023 · 4 shares · 20 followers View post →

Szu Shuo Lee

@ShuoSzu · X

RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…

Jul 21, 2023 · 4 shares · 156 followers View post →

Northeastern University Bioengineering

@NUBioE1 · X

RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…

Jul 21, 2023 · 4 shares · 613 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

Jul 21, 2023 · 19 likes · 4 shares · 19,970 followers View post →

Single-Cell Proteomics Conference

@SCP_meeting · X

RT @slavov_n: We also discussed this at the 2019 @SCP_meeting: https://t.co/NdkV6wSbDf https://t.co/bA8QdGodr2

Jun 28, 2023 · 1 share · 2,196 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

We also discussed this at the 2019 @SCP_meeting: https://t.co/NdkV6wSbDf https://t.co/bA8QdGodr2

Jun 28, 2023 · 1 like · 1 share · 19,787 followers View post →

Selima Webb

@selimawebb · X

RT @slavov_n: It's remarkable to see how much of #HUPO2022 is devoted to single-cell proteomics, technologies and method development. I wo…

Dec 2, 2022 · 2 shares · 77 followers View post →

Pastel BioScience

@PastelBio · X

RT @slavov_n: It's remarkable to see how much of #HUPO2022 is devoted to single-cell proteomics, technologies and method development. I wo…

Dec 1, 2022 · 2 shares · 5,376 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

It's remarkable to see how much of #HUPO2022 is devoted to single-cell proteomics, technologies and method development. I would love to see these efforts delivering on the biological promises that motivated it from the very beginning. https://t.co/peylTx0OXy

Dec 1, 2022 · 5 likes · 2 shares · 19,970 followers View post →

lbgbox

@lbgbox · X

RT @slavov_n: I gave this talk at @cshlmeetings 5 years ago. It was a turbulent & exciting time for single-cell proteomics my mass-spec.…

Nov 16, 2022 · 4 shares · 51 followers View post →

Ron Finn

@Finnsense · X

RT @slavov_n: I gave this talk at @cshlmeetings 5 years ago. It was a turbulent & exciting time for single-cell proteomics my mass-spec.…

Nov 15, 2022 · 4 shares · 1,121 followers View post →

Mustafa

@must426 · X

RT @slavov_n: I gave this talk at @cshlmeetings 5 years ago. It was a turbulent & exciting time for single-cell proteomics my mass-spec.…

Nov 15, 2022 · 4 shares · 56 followers View post →

Prof(ret.) Dr Rune Linding 

@RuneLinding · X

RT @slavov_n: I gave this talk at @cshlmeetings 5 years ago. It was a turbulent & exciting time for single-cell proteomics my mass-spec.…

Nov 15, 2022 · 4 shares · 3,019 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

I gave this talk at @cshlmeetings 5 years ago. It was a turbulent & exciting time for single-cell proteomics my mass-spec. https://t.co/ElpEIO3f0E has caused a stir but many colleagues did not yet believe mass-spec was sensitive enough.

Nov 15, 2022 · 16 likes · 4 shares · 19,787 followers View post →

Slavov Laboratory

@slavovLab · X

RT @slavov_n: The 2022 Google Metrics are out https://t.co/gALibbmuNr Several papers from @slavovLab are listed within the h5-indices of t…

Jul 10, 2022 · 1 share · 2,828 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

The 2022 Google Metrics are out https://t.co/gALibbmuNr Several papers from @slavovLab are listed within the h5-indices of their journals, including: https://t.co/peylTx0OXy at @JProteomeRes https://t.co/EXrnHYM17V at @PLOSCompBiol https://t.co/cAKLET86Wd at @GenomeBiology

Jul 9, 2022 · 4 likes · 1 share · 19,970 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

@J_my_sci There are other approaches as well, including spiked in peptides, fluorescent proteins. Showing high repeatability and no accuracy estimates can be rather misleading. I think that is a very important issue and have emphasized it at @SCP_meeting workshops https://t.co/ZOVGTE9UcB https://t.co/cqQm7qtmjX

Nov 11, 2021 · 1 like · 19,787 followers View post →

Uthpala Seneviratne

@UthpalaISen · X

RT @slavov_n: At a 2017 CSHL meeting, I talked about the benefits of multiplexing for single-cell proteomics https://t.co/wCrawtlVzm Yet,…

Nov 1, 2021 · 5 shares · 146 followers View post →

Amit Kumar Yadav

@theoneamit · X

RT @slavov_n: At a 2017 CSHL meeting, I talked about the benefits of multiplexing for single-cell proteomics https://t.co/wCrawtlVzm Yet,…

Oct 31, 2021 · 5 shares · 1,423 followers View post →

Single Cell Media

@SingleCellMedia · X

RT @slavov_n: At a 2017 CSHL meeting, I talked about the benefits of multiplexing for single-cell proteomics https://t.co/wCrawtlVzm Yet,…

Oct 31, 2021 · 5 shares · 3,840 followers View post →

Andrew Leduc

@_AndrewLeduc · X

RT @slavov_n: At a 2017 CSHL meeting, I talked about the benefits of multiplexing for single-cell proteomics https://t.co/wCrawtlVzm Yet,…

Oct 31, 2021 · 5 shares · 576 followers View post →

Vadim Demichev

@DemichevLab · X

RT @slavov_n: At a 2017 CSHL meeting, I talked about the benefits of multiplexing for single-cell proteomics https://t.co/wCrawtlVzm Yet,…

Oct 31, 2021 · 5 shares · 3,582 followers View post →

Prof. Nikolai Slavov

@slavov_n · X

Oct 31, 2021 · 19 likes · 5 shares · 19,787 followers View post →

Joel Steele

@JoelisSteele · X