Our article about HyMS microscopy is the featured resource article in today's issue of @CellCellPress https://t.co/5d2omhahMW https://t.co/nASmTSHLLS
Volumetric Ca Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy.
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Apr 2019 – Sep 2021Where it's discussed
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News14 articles
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X / Twitter6 posts
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Blogs6 articles
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Facebook4 posts
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What people are saying
The discussions reflect a generally positive reception, with several posts praising the reproducibility efforts such as including RRIDs and recognizing the article as a featured resource in a prestigious journal. Phrases like 'appreciate' and 'thank you' convey support, while mentions of the technical innovation like 'using 2P and 3P concurrently' highlight interest in the method's capabilities, suggesting that the community values the potential for advancing neuroscience research.
Most discussions express positive acknowledgment of the publication's contributions, especially highlighting the importance of reproducibility and technical advancements.
The discussions demonstrate high interest by emphasizing the innovative aspects of HyMS microscopy and its potential applications in neuroscience.
Posts show moderate engagement, with some referencing specific techniques like RRID inclusion and the feature in the journal, but lacking deep analysis or critique.
Users seem to see the work as impactful within the scientific community, though the discussions center around acknowledgment rather than widespread application or change.
Abstract in brief
- This study introduces a new hybrid multiplexed sculpted light microscopy technique for calcium imaging in the mouse brain, overcoming traditional limitations like limited field of view, slow acquisition speed, and depth restrictions in scattering tissue.
- The system is modular and can perform volumetric recordings at single-cell resolution within large brain areas (up to 1,122 mm³) at a high speed of 17Hz, even in awake, behaving mice.
- The researchers demonstrated the system's capabilities by successfully recording activity from up to 12,000 neurons across various brain regions, such as the auditory cortex, posterior parietal cortex, and hippocampus, highlighting its potential for detailed in vivo neuroscience studies.]
Top posts
Most liked on X and BlueskyHybrid multiplexed sculpted light #Microscopy (HyMS) uses 2P and 3P concurrently to allow volumetric recording of neuroactivity at #SingleCell resolution! https://t.co/96NryUU6QD
https://t.co/recC5DF4GS
The authors of "Volumetric Ca2+ Imaging in the Mouse Brain Using H…" (https://t.co/rf8qWwqK2t) included RRIDs in their paper! We appreciate the author's support of reproducibility. #OpenScience #RRID
The authors of "untitled" (https://t.co/rf8qWw98DT) included RRIDs in their paper! Thank you for making your #methodsmatter. #reproducibility
RRIDs were included in the Cell paper "untitled" (https://t.co/rf8qWw98DT). We appreciate the author's support of reproducibility. #reproducibility #ReproducibleResearch
All mentions
Advanced Multiplexed Light Microscopy for Neuronal Calcium Imaging in Mice
This video introduces a hybrid multiplexed sculpted light microscopy technique for calcium imaging in the mouse brain, enabling volumetric recordings at single-cell resolution across large areas at high speed in awake…
Advanced Calcium Imaging Technique for In Vivo Neuronal Activity Analysis
This video discusses a new hybrid multiplexed sculpted light microscopy system that enables volumetric calcium imaging in the mouse brain, capturing activity from thousands of neurons across multiple regions with high…
The authors of "Volumetric Ca2+ Imaging in the Mouse Brain Using H…" (https://t.co/rf8qWwqK2t) included RRIDs in their paper! We appreciate the author's support of reproducibility. #OpenScience #RRID
The authors of "untitled" (https://t.co/rf8qWw98DT) included RRIDs in their paper! Thank you for making your #methodsmatter. #reproducibility
RRIDs were included in the Cell paper "untitled" (https://t.co/rf8qWw98DT). We appreciate the author's support of reproducibility. #reproducibility #ReproducibleResearch
Our article about HyMS microscopy is the featured resource article in today's issue of @CellCellPress https://t.co/5d2omhahMW https://t.co/nASmTSHLLS
Hybrid multiplexed sculpted light #Microscopy (HyMS) uses 2P and 3P concurrently to allow volumetric recording of neuroactivity at #SingleCell resolution! https://t.co/96NryUU6QD
https://t.co/recC5DF4GS