The overall discussions show enthusiasm and support, with mentions of the review's focus on mechanistic simplifications, such as 'dimensionality reduction' and 'self-organization,' which highlight both interest and engagement. Words like 'discuss' and 'Have a look' signal active scientific curiosity, contributing to the perception of moderate impact within the scientific community.
AgreementModerate agreement
Most discussions express support or positive acknowledgment of the article, such as the mention that the review has 'appeared' and covers concepts like dimensionality reduction and self-organization, indicating agreement with the importance or validity of
InterestHigh interest
The conversation shows strong curiosity, with posts highlighting key aspects like the mechanics, self-organization, and simplification of complex protein behaviors; notably, phrases such as 'Have a look' and referencing interesting topics suggest high int
EngagementModerate engagement
Posts reference specific scientific topics and encourage further reading, reflecting active engagement, especially the mention of 'dimensionality reduction' and the paper's role in explaining protein functions.
ImpactModerate impact
While it's mostly supportive discussions, the review's potential to influence understanding and future research in protein mechanics gives it moderate impact, supported by posts emphasizing its relevance to understanding biological machines.
Abstract in brief
Protein machines are tiny, complex systems that typically require powerful supercomputers to fully understand their cycles, which take weeks to analyze.
Despite their complexity, many features of these proteins can be explained using simple mechanical models that treat them as elastic networks.
The study shows that the collective behavior of these proteins can be simplified to a low-dimensional space, making their function easier to analyze and understand.]
Our review 'Simple mechanics of protein machines' has now appeared. We discuss e.g. dimensionality reduction and self-organization effects. Have a look https://t.co/omQombLUoL
Jun 21, 2019 · 1 like · 2 shares · 9 followersView post →
R飯
Ryota IINO 飯野亮太
@ryotaiino · X
RT @HolgerFlechsig: Our review 'Simple mechanics of protein machines' has now appeared. We discuss e.g. dimensionality reduction and self-o…
Jun 21, 2019 · 2 shares · 6,465 followersView post →
マ世
マーキュリー２世
@uranus_2 · X
タンパク質機構に関するレビュー。Simple mechanics of protein machines https://t.co/yoUjaWawh0
#Coronavirus hijacks the cells micro machines to build new copies of itself. Here is an introduction to them and a paper that shows how the machines could work.
https://t.co/nUkDVOqODf
https://t.co/QrUduE1NBn
This simulation shows the ATP-dependent conformational motions in the hepatitis C virus helicase protein motor. Using a simplified elastic network model, the study demonstrates how the helicase unzips DNA by translating…
Simulation of an elastic network functioning as a protein motor transporting a filament through ratchet mechanisms. The model translates cyclic conformational changes into unidirectional filament movement, providing…
This simulation shows the ATP-dependent conformational motions in the hepatitis C virus helicase protein motor. Using an inchworm ratchet mechanism, the motor translocates unidirectionally along DNA by cycling through…
An elastic network with ordered collective domain motions models a machine powered by ligands. It cyclically changes conformation after binding, converting and releasing ligands, illustrating ligand-induced…
The active dimer model uses ligand-induced motions to simulate molecular motor operations, translating cyclic protein motions into steady filament transport through a ratchet mechanism, providing insight into protein…
Simulation of an elastic network operating as a model protein machine in a lipid bilayer membrane. This system serves as a structurally resolved model of active membrane inclusions, revealing mechanochemical motions…
#Coronavirus hijacks the cells micro machines to build new copies of itself. Here is an introduction to them and a paper that shows how the machines could work.
https://t.co/nUkDVOqODf
https://t.co/QrUduE1NBn
RT @HolgerFlechsig: Our review 'Simple mechanics of protein machines' has now appeared. We discuss e.g. dimensionality reduction and self-o…
Jun 21, 2019 · 2 shares · 665 followersView post →
R飯
Ryota IINO 飯野亮太
@ryotaiino · X
RT @HolgerFlechsig: Our review 'Simple mechanics of protein machines' has now appeared. We discuss e.g. dimensionality reduction and self-o…
Jun 21, 2019 · 2 shares · 6,465 followersView post →
HF
Holger Flechsig
@HolgerFlechsig · X
Our review 'Simple mechanics of protein machines' has now appeared. We discuss e.g. dimensionality reduction and self-organization effects. Have a look https://t.co/omQombLUoL
Jun 21, 2019 · 1 like · 2 shares · 9 followersView post →
マ世
マーキュリー２世
@uranus_2 · X
タンパク質機構に関するレビュー。Simple mechanics of protein machines https://t.co/yoUjaWawh0
org/doi/10.1098/rsif.2019.0244 Cito: "En gran medida, la célula viva es una población de máquinas moleculares que interactúan [ 1 ]. Estas máquinas ...
org/doi/10.1098/rsif.2019.0244 Cito: "En gran medida, la célula viva es una población de máquinas moleculares que interactúan [ 1 ]. Estas máquinas ...
HF
R飯
マ世
NR
TK