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The choices reflect a generally optimistic view, with posts emphasizing SCoPE2's innovations and implications, such as comments on its high throughput and potential to deepen understanding of macrophage diversity, using enthusiastic terms like 'game changer' and noting the method's ability to uncover protein variability in single cells.
Majority of discussions praise the significance and technological advancement of the SCoPE2 approach, reflecting a shared positive stance.
Posts demonstrate high interest, with mentions of the method's implications and integration with other techniques like RNA analysis.
Several contributions cite specific methods, datasets, and applications, indicating deep involvement and understanding.
The discussions highlight that SCoPE2 could significantly influence future cell biology research, especially in understanding cell heterogeneity.
Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth and throughput of single cell proteomics analysis. Highlight: https://t.co/pF52II32de Original research: https://t.co/uHPq24WZb2 https://t.co/aNvvY2zfZh https://t.co/2ixvbXD4Fp
New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4oGV now published in @GenomeBiology
The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, including: https://t.co/cAKLET86Wd at Genome Biology https://t.co/8Agmu0HjiO at Genome Biology https://t.co/peylTx0OXy at J. Proteome Res. Genome Biology https://t.co/dHS8WGCy7o
@willmacnair RNA-seq has been shown to be a *pretty good* proxy for protein level (e.g. https://t.co/Hx7GrJb4hE). It's not perfect but gives us likely true results to be validated experimentally.
@OdedRechavi Or with a PhD student. @harrisonspecht is a corresponding author for our paper https://t.co/8Agmu0HjiO
@mjmaccoss @r_l_moritz @chrashwood Very few LC-MS/MS studies report copy numbers counted by peptide or proteoform. We started doing it in the context of single-cell proteomics after Makarov taught us a simple approach to esteeming copy numbers: https://t.co/8Agmu0HjiO & https://t.co/DZ0E7vC6lR Still, it has not https://t.co/FaZ0xpITZd
This lecture on dimensionality reduction was presented by Prof Nikolai Slavov and is part of the course httpsslavovlabnetstats. It discusses methods for reducing data complexity, essential for analyzing high-dimensional…
Current single-cell mass spectrometry methods can analyze thousands of peptides per cell, with potential advancements allowing detection of 10 times more peptides. Innovations in data acquisition and analysis are key to…
Current mass spectrometry methods analyze thousands of peptides per cell, with potential for tenfold increases. Innovations in data acquisition, analysis, and instrumentation are key to improving coverage, accuracy, and…
Nikolai Slavov discusses optimizing single-cell analysis of proteins and RNAs, focusing on improving reliability, depth, and throughput. The presentation highlights recent developments like SCoPE2 for detailed study of…
Single-cell protein analysis is challenging due to low sensitivity and throughput, although mass spectrometry is a powerful tool for detection. Recent methods like SCoPE, multiplexing, and automation have improved the…
This presentation by Prof. Nikolai Slavov explores advances in single-cell proteomics, revealing cellular complexity and heterogeneity. Understanding single-cell proteomes is crucial for breakthroughs in cancer research…
RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…
RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…
RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…
RT @slavov_n: The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, inclu…
The 2023 Google Metrics are out, and several papers from @slavovLab are listed within the h5-indices of their journals, including: https://t.co/cAKLET86Wd at Genome Biology https://t.co/8Agmu0HjiO at Genome Biology https://t.co/peylTx0OXy at J. Proteome Res. Genome Biology https://t.co/dHS8WGCy7o
RT @slavov_n: @mjmaccoss @r_l_moritz @chrashwood Very few LC-MS/MS studies report copy numbers counted by peptide or proteoform. We starte…
RT @slavov_n: @mjmaccoss @r_l_moritz @chrashwood Very few LC-MS/MS studies report copy numbers counted by peptide or proteoform. We starte…
@mjmaccoss @r_l_moritz @chrashwood Very few LC-MS/MS studies report copy numbers counted by peptide or proteoform. We started doing it in the context of single-cell proteomics after Makarov taught us a simple approach to esteeming copy numbers: https://t.co/8Agmu0HjiO & https://t.co/DZ0E7vC6lR Still, it has not https://t.co/FaZ0xpITZd
@willmacnair RNA-seq has been shown to be a *pretty good* proxy for protein level (e.g. https://t.co/Hx7GrJb4hE). It's not perfect but gives us likely true results to be validated experimentally.
@GarciaLabMS @BenAndoSays .@BenAndoSays, it is easy to combine single-cell RNA and protein analysis if that is what your project requires. It can be done by dataset alignment, as we did in the SCoPE2 article https://t.co/8Agmu0HjiO or by measuting both in the same cell - methods for that are forthcoming.
and proteomics (scope2) https://t.co/Vvtbbfs5EN by @slavov_n @harrisonspecht et al
RT @slavov_n: The 2022 edition by @quantixed lists many good papers from the last year worth reading. I was pleased to find our single-c…
RT @slavov_n: The 2022 edition by @quantixed lists many good papers from the last year worth reading. I was pleased to find our single-c…
The 2022 edition by @quantixed lists many good papers from the last year worth reading. I was pleased to find our single-cell proteomic and transcriptomic analysis of macrophages on the list https://t.co/8Agmu0HjiO https://t.co/UhX8B4dFcm
@J_my_sci I would have suggested comparing relative protein levels estimated from single cells to those estimates from bulk samples, e.g., similar to this analysis in figure 4c https://t.co/Ktf11Sqy5q
@Sanjusinha7 Agreed. By the way, this amazing SCoPE2 paper may provide us more insights
RT @c_vanderaa: We demonstrate our software by replicating the data analysis of the SCoPE2 macrophage dataset from the @slavovLab. Many tha…
RT @c_vanderaa: We demonstrate our software by replicating the data analysis of the SCoPE2 macrophage dataset from the @slavovLab. Many tha…
RT @c_vanderaa: We demonstrate our software by replicating the data analysis of the SCoPE2 macrophage dataset from the @slavovLab. Many tha…
RT @c_vanderaa: We demonstrate our software by replicating the data analysis of the SCoPE2 macrophage dataset from the @slavovLab. Many tha…
RT @c_vanderaa: We demonstrate our software by replicating the data analysis of the SCoPE2 macrophage dataset from the @slavovLab. Many tha…
We demonstrate our software by replicating the data analysis of the SCoPE2 macrophage dataset from the @slavovLab. Many thanks to @slavov_n, @harrisonspecth and @edemmott for making the effort of #openscience and addressing our questions! https://t.co/VnGVn2QC5E
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 https://t.co/NcpLeiEMtr
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
RT @naturemethods: Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth…
Research Highlight by @DrArunimaSingh: recently developed approaches from @slavovLab and @erwinschoof increase the depth and throughput of single cell proteomics analysis. Highlight: https://t.co/pF52II32de Original research: https://t.co/uHPq24WZb2 https://t.co/aNvvY2zfZh https://t.co/2ixvbXD4Fp
@tnobo_ktcs https://t.co/6urdvwU1Sy https://t.co/9Nre0F5rMs https://t.co/GNb4FJYDuX https://t.co/l9aaWhcSIo
RT @slavov_n: Preprints accelerate communication: Before our SCoPE2 diagram appeared in a journal article authored by us, it appeared in…
Preprints accelerate communication: Before our SCoPE2 diagram appeared in a journal article authored by us, it appeared in journal articles authored by others. The diagrams in our preprint (https://t.co/bbicPDhj6l) and journal (https://t.co/8Agmu0YUam) articles are identical. https://t.co/u1W1AtnceD
RT @aurel_pasturel: Following their last paper: https://t.co/1MD4INUjzW on #singlecell #proteomics @_AndrewLeduc, R. Gray Huffman & @slavo…
RT @aurel_pasturel: Following their last paper: https://t.co/1MD4INUjzW on #singlecell #proteomics @_AndrewLeduc, R. Gray Huffman & @slavo…
@sandakano Here are a few: https://t.co/KdbMtJj0MO snDrop-seq and single-cell transposome hypersensitive site sequencing (scTHS-seq) https://t.co/SG6LXttaJe Single-cell proteomic and transcriptomic analysis https://t.co/o5WfKod86W Shared Single-Cell Profiling of RNA and Chromatin
RT @slavov_n: @OdedRechavi Or with a PhD student. @harrisonspecht is a corresponding author for our paper https://t.co/8Agmu0HjiO
@OdedRechavi Or with a PhD student. @harrisonspecht is a corresponding author for our paper https://t.co/8Agmu0HjiO
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @GenomeBiology: SCoPE2, a single-cell proteomics approach using mass spec, from @harrisonspecht, @slavov_n and co. SCoPE2 improves the t…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @sroyyors: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 https://t.co/3LUz8H4PSB
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 https://t.co/3LUz8H4PSB
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @rnomics: Top #tweeted story in #bioscience: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2…
RT @rnomics: Top #tweeted story in #bioscience: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2…
RT @rnomics: Top #tweeted story in #bioscience: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2…
RT @rnomics: Top #tweeted story in #bioscience: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @jsantoyo: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. #SingleCell https://t.co/GQDT9ei…
RT @jsantoyo: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. #SingleCell https://t.co/GQDT9ei…
RT @jsantoyo: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. #SingleCell https://t.co/GQDT9ei…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @rnomics: Top #tweeted story in #bioscience: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @GenomeBiology: SCoPE2, a single-cell proteomics approach using mass spec, from @harrisonspecht, @slavov_n and co. SCoPE2 improves the t…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @GenomeBiology: SCoPE2, a single-cell proteomics approach using mass spec, from @harrisonspecht, @slavov_n and co. SCoPE2 improves the t…
RT @GenomeBiology: SCoPE2, a single-cell proteomics approach using mass spec, from @harrisonspecht, @slavov_n and co. SCoPE2 improves the t…
RT @GenomeBiology: SCoPE2, a single-cell proteomics approach using mass spec, from @harrisonspecht, @slavov_n and co. SCoPE2 improves the t…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @GenomeBiology: SCoPE2, a single-cell proteomics approach using mass spec, from @harrisonspecht, @slavov_n and co. SCoPE2 improves the t…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @slavov_n: Our joint single-cell analysis of proteins & RNAs in differentiating macrophages appeared in @GenomeBiology https://t.co/8Agm…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
RT @emmottlab: New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4o…
New paper: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. https://t.co/u5zF1B4oGV now published in @GenomeBiology
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