Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
Increasing the throughput of sensitive proteomics by plexDIA.
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Nov 2021 – Nov 2025Where it's discussed
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X / Twitter99 posts
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YouTube12 videos
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Blogs5 articles
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News3 articles
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What people are saying
Overall, the discussions reflect a high level of enthusiasm and support, with examples such as the mention of plexDIA increasing proteomics throughput and references to presentations by notable researchers like Prof. Slavov. The tone is technical yet optimistic, emphasizing the transformative potential of this framework for sensitive proteomics and single-cell analysis.
Most discussions express strong support for the publication, highlighting its significance and potential to advance proteomics technology.
The majority of discussions demonstrate high interest, with references to detailed techniques and enthusiasm for the framework's benefits.
Users engage deeply by referencing specific methods like plexDIA, mentioning related presentations, and asking reflective questions about the field's progress.
Many discussions imply that the study could revolutionize proteomics, especially for small samples, increasing throughput and detection capabilities in single-cell analysis.
Abstract in brief
- Current mass spectrometry methods excel in high-throughput proteomics for large samples but struggle with low sample amounts, limiting depth and throughput.
- Researchers developed plexDIA, a new framework that enables simultaneous multiplexing of peptide and sample analysis, significantly boosting throughput without sacrificing proteome coverage or accuracy.
- plexDIA's use of three-plex non-isobaric mass tags allows for the quantification of more protein ratios in small samples, achieving impressive data completeness and enabling detailed analysis of proteins in single human cells.
Top posts
Most liked on X and BlueskySampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️ All proteomic technologies face it. Below are our thoughts on how to overcome it
I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CSTKeZ5L9P https://t.co/Rg0oN8c0Br
A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that increases the throughput of sensitive #proteomics by simultaneously multiplexing the analysis of peptides and samples. @slavov_n ❔ Q&A: https://t.co/mrpWMDw62a https://t.co/nxNGHL5gZ5
Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t.co/yjktRumYtZ
We focussed on: ◼️ What is the number of protein molecules that single-molecule proteomics methods need to count to achieve comprehensive proteome coverage ? ◼️ What strategies may reduce this number ? We briefly discussed these Qs at @SCP_meeting https://t.co/lhwLbEkLuK
All mentions
Advances in Single-Cell Proteomics Using Mass Spectrometry Techniques
This lecture introduces single-cell proteomics by mass spectrometry, highlighting plexDIA's high-throughput multiplexing capabilities for small samples, enabling detailed protein analysis in individual human cells.
Advancements in Single-Cell Protein Analysis Using Mass Spectrometry
Prof. Nikolai Slavov discusses innovations in single-cell mass spectrometry, highlighting methods to increase peptide detection, improve data accuracy, and advance biomedical research through enhanced instrumentation…
Single-cell Mass Spectrometry Proteomics Data Acquisition and Analysis Techniques
Workshop on single-cell mass spectrometry proteomic data acquisition using plexDIA and timsTOF, with initial interpretation via QuantQC, held at SCP2024. Focuses on improving data quality by minimizing protein leakage…
Advancements in Single-Cell Proteomics with plexDIA Technology
Exploring new methodologies for sensitive protein analysis in single cells, focusing on plexDIA's framework that enhances throughput, accuracy, and proteome coverage for low sample amounts.
Advances in Single-Molecule Proteomics for Detailed Cell Analysis
New methods in single-molecule protein detection are improving how scientists analyze proteins at a very detailed level, allowing for more thorough study of individual cells. These advances aim to increase detection…
Advancements in Single-Cell Proteomics with plexDIA Technology
Prof. Nikolai Slavov discusses plexDIA, a new method boosting throughput and proteome coverage in single-cell proteomics through multiplexing, enabling detailed analysis of proteins in individual human cells.
Proteomics Insights: Single-Cell Variation and Molecular Mechanisms
This presentation explores proteome variation at the single-cell level and the underlying molecular mechanisms. It discusses progress in proteomics, analyzing over 1000 human samples, revealing significant amino acid…
Enhancing Single-Cell Proteomics with Trapped Ion Mobility Technology
This presentation discusses trapped ion mobility's benefits for single-cell proteomics, enabling higher throughput and improved accuracy. It highlights the plexDIA framework that integrates multiplexing to analyze small…
Regulators of Protein Transport Revealed by Single-Nucleus Proteomics
Presentation by Dr. Jason Derks at SCP2024 discussing how singlenucleus proteomics identifies regulators of protein transport, leveraging multiplexed analysis to enhance proteome coverage and accuracy in small samples…
Enhancing Protein Analysis with plexDIA and MaxQuant
This presentation by Prof. Juergen Cox at the 7th Single Cell Proteomics Conference discusses sensitive and accurate plexDIA techniques using MaxQuant. The talk highlights recent advancements in library-based and…
Advancements in Single-Cell Proteomics with plexDIA Methodology
The video discusses advancements in single-cell proteomics using mass spectrometry focusing on overcoming current limitations. plexDIA is highlighted as a framework for increasing throughput and sensitivity…
Enhancing Single-Cell Proteomics: Techniques and Data Interpretation
Making the larger is challenging, but we may be able to host more workshops. We recorded the last one, so at least we can share a recording on YouTube. https://t.co/gqJUlhAI3e
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
RT @slavov_n: Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️…
Sampling a sufficient number of protein molecules to cover the huge dynamic ranges of the proteome is a common challenge. ◼️ All proteomic technologies face it. Below are our thoughts on how to overcome it
RT @ParallelSqTech: A recording of our @SCP_meeting workshop is up on YouTube: Data acquisition and initial interpretation for single-cell…
RT @ParallelSqTech: A recording of our @SCP_meeting workshop is up on YouTube: Data acquisition and initial interpretation for single-cell…
A recording of our @SCP_meeting workshop is up on YouTube: Data acquisition and initial interpretation for single-cell proteomics by mass spectrometry. Thanks to @_AndrewLeduc and team for leading it! https://t.co/OwiKrmkIYe
RT @SCP_meeting: The talk by Dr. Jason Derks (@_JasonDerks) at #SCP2024 is on YouTube: Single-nucleus proteomics identifies regulators o…
Sensitive and accurate plexDIA with @maxquant A presentation by Prof. Juergen Cox (@TheCoxLab) at #SCP2024 https://t.co/9jpjyPqHfG
RT @slavovLab: Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t…
RT @SCP_meeting: The talk by Dr. Jason Derks (@_JasonDerks) at #SCP2024 is on YouTube: Single-nucleus proteomics identifies regulators o…
The talk by Dr. Jason Derks (@_JasonDerks) at #SCP2024 is on YouTube: Single-nucleus proteomics identifies regulators of protein transport. Preprint: https://t.co/2IJYEIs6f1 Talk: https://t.co/I8qqVFyvjG
RT @slavovLab: Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t…
RT @slavovLab: Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t…
RT @slavovLab: Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t…
RT @slavovLab: Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t…
Single-molecule proteomics can greatly benefit from separation. A talk from @SCP_meeting: https://t.co/BQTRXMc60G https://t.co/yjktRumYtZ
Here is my reflection on it in 2022, asking a question: ◼️ Could we have started 10 years earlier ? https://t.co/5WrIRLNSdt https://t.co/Mgdk2ClF1m
The talk by Dr. Matthew Willetts at #SCP2023 is on YouTube: The benefits of trapped ion mobility for single-cell proteomics https://t.co/VM9srMknWi
RT @slavov_n: We discussed these issues at @SCP_meeting last year: https://t.co/lhwLbEljki
RT @slavov_n: We discussed these issues at @SCP_meeting last year: https://t.co/lhwLbEljki
We discussed these issues at @SCP_meeting last year: https://t.co/lhwLbEljki
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/9NpAZMYEXo
Increasing the throughput of sensitive proteomics by plexDIA | Nature Biotechnology https://t.co/DNWXWlU1h2 #proteomics
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/9y0ioItRvy
RT @slavov_n: We focussed on: ◼️ What is the number of protein molecules that single-molecule proteomics methods need to count to achieve…
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
We focussed on: ◼️ What is the number of protein molecules that single-molecule proteomics methods need to count to achieve comprehensive proteome coverage ? ◼️ What strategies may reduce this number ? We briefly discussed these Qs at @SCP_meeting https://t.co/lhwLbEkLuK
RT @ScienceinBoston: A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that incre…
RT @ScienceinBoston: A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that incre…
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @ScienceinBoston: A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that incre…
RT @ScienceinBoston: A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that incre…
A @NatureBiotech paper from @_JasonDerks and a team in the @SlavovLab introduces a framework called plexDIA that increases the throughput of sensitive #proteomics by simultaneously multiplexing the analysis of peptides and samples. @slavov_n ❔ Q&A: https://t.co/mrpWMDw62a https://t.co/nxNGHL5gZ5
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
Increasing the throughput of sensitive proteomics by plexDIA | https://t.co/Fw9umPRN1u #proteomics https://t.co/4lwvW7f2nJ
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @CDProteomics: Increasing the throughput of sensitive proteomics by plexDIA Proteomics of small sample sizes using data-independent acqu…
Increasing the throughput of sensitive proteomics by plexDIA Proteomics of small sample sizes using data-independent acquisition methods achieves higher throughput with multiplexing. https://t.co/whQZ6kBfiW
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @SCP_meeting: Exploring functional protein covariation across single cells A presentation by Prof. Slavov (@slavov_n) at the 5th single…
Exploring functional protein covariation across single cells A presentation by Prof. Slavov (@slavov_n) at the 5th single-cell proteomics conference #SCP2022. https://t.co/5O00FqDcWL
TW : Increasing the throughput of sensitive proteomics by plexDIA: ...which receives its core funding from Cancer Research UK (FC001134); the UK Medical Research Council (FC001134); and the... https://t.co/3LZ6rAYmXi https://t.co/cTKaKYGry9
RT @realBioMassSpec: Increasing the throughput of sensitive proteomics by plexDIA #NatBiotechnol #MassSpec https://t.co/BYFvudKXI9
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
Increasing the throughput of sensitive proteomics by plexDIA #NatBiotechnol #MassSpec https://t.co/BYFvudKXI9
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @SCP_meeting: Overcoming the dynamic-range challenge of the human proteome A presentation by Prof. Nikolai Slavov (@slavov_n) at the 5t…
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
RT @NatureBiotech: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CZA27dr3Iw https://t.co/RFgnGECg2V
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/2HfLQecrfJ #nature #MassSpecPub https://t.co/wyMA7jTG7Q
RT @SCP_meeting: Overcoming the dynamic-range challenge of the human proteome A presentation by Prof. Nikolai Slavov (@slavov_n) at the 5t…
Overcoming the dynamic-range challenge of the human proteome A presentation by Prof. Nikolai Slavov (@slavov_n) at the 5th single-cell proteomics conference #SCP2022. https://t.co/umHpoNt9gV
RT @SourceEsi: Today at 11am EST - Join EMERGE Episode 8 with Jason Derks - “Increasing the throughput of sensitive proteomics by plexDIA”…
Today at 11am EST - Join EMERGE Episode 8 with Jason Derks - “Increasing the throughput of sensitive proteomics by plexDIA” Register and join free now: https://t.co/EPtXZCBP4N #webinar #emerge #plexDIA #proteomics https://t.co/LRSdkFFjpA
RT @StoyanStoychev1: Please join us for EMERGE Ep 8 with @_JasonDerks from the @slavovLab: "Increasing the throughput of sensitive proteomi…
RT @StoyanStoychev1: Please join us for EMERGE Ep 8 with @_JasonDerks from the @slavovLab: "Increasing the throughput of sensitive proteomi…
RT @StoyanStoychev1: Please join us for EMERGE Ep 8 with @_JasonDerks from the @slavovLab: "Increasing the throughput of sensitive proteomi…
Please join us for EMERGE Ep 8 with @_JasonDerks from the @slavovLab: "Increasing the throughput of sensitive proteomics by plexDIA" (27 April 17:00 CET, 11:00am EDT) - *|https://t.co/hAmZ5uozpa|* https://t.co/qkuxOqDELJ
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/mJ8Nuge3GC
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/rEpcdrdJX1
RT @PromPreprint: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/kJd9G7YCoJ
RT @biorxivpreprint: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/EUhlLaVZPp #bioRxiv
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @PastelBio: multiplexed DIA: plexDIA Increasing the throughput of sensitive proteomics by plexDIA | https://t.co/L0kF3gcFba #proteomics…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @_JasonDerks: I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of…
RT @PastelBio: multiplexed DIA: plexDIA Increasing the throughput of sensitive proteomics by plexDIA | https://t.co/L0kF3gcFba #proteomics…
RT @PastelBio: multiplexed DIA: plexDIA Increasing the throughput of sensitive proteomics by plexDIA | https://t.co/L0kF3gcFba #proteomics…
multiplexed DIA: plexDIA Increasing the throughput of sensitive proteomics by plexDIA | https://t.co/L0kF3gcFba #proteomics and article https://t.co/dEFta5UZHy https://t.co/7DxNM1y3My
RT @biorxivpreprint: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/EUhlLaVZPp #bioRxiv
I'm very excited to share the work we've done @slavovLab in collaboration with @DemichevLab! Increasing the throughput of sensitive proteomics by plexDIA https://t.co/CSTKeZ5L9P https://t.co/Rg0oN8c0Br
RT @biorxivpreprint: Increasing the throughput of sensitive proteomics by plexDIA https://t.co/EUhlLaVZPp #bioRxiv
Increasing the throughput of sensitive proteomics by plexDIA https://t.co/7YvOnbmiyn #biorxiv_sysbio
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