Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, Dalila Ajjaji, and all authors Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation https://t.co/NtbbW6yLXm
Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation.
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Mar 2023 – Sep 2023Where it's discussed
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X / Twitter21 posts
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YouTube1 videos
AI synopsis
What people are saying
The group shows enthusiasm for the study, highlighting its relevance through phrases like 'structural insights' and 'collaborative study.' The mention of conference posters and preprints illustrates active engagement and interest, while references to lipid-protein interactions emphasize the perceived significance of the findings in the field.
Most discussions express approval and recognition of the significance of the research, supporting its contributions.
Numerous mentions of conference presentations, posters, and preprints indicate high interest in the topic and findings.
Posts include references to specific details like the protein PLIN3, membrane interactions, and experimental methods, showing active engagement.
There is a recognition that the study advances understanding of lipid membrane dynamics, which could influence future research directions.
Abstract in brief
- The study explores how lipid composition, specifically molecules like phosphatidic acid and diacylglycerol (DAG), influences the recruitment of perilipin 3 (PLIN3) to membranes and lipid droplets during their formation.
- When PLIN3 binds to DAG-enriched membranes, it causes structural changes in its PAT domain, shifting from a disordered to a more ordered, folded but dynamic structure.
- In cells, PLIN3 is directed to DAG-rich endoplasmic reticulum membranes through interactions involving the PAT domain and 11mer repeats, highlighting how certain lipids and protein domains work together to facilitate lipid droplet formation.]
Top posts
Most liked on X and Blueskyif you're at the #deuel conference make sure to check out Yong Mi's poster on perilipin 3 membrane association! if you're not, check out the preprint: Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation https://t.co/IjsUFaHpdF https://t.co/bodf5bnFn8
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
All mentions
Structural Analysis of Perilipin 3 Membrane Association in Lipid Droplet Formation
This video explores how lipid composition influences perilipin 3 recruitment to membranes and lipid droplets, highlighting structural changes in the PAT domain during DAG-enriched membrane binding and its role in lipid…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
RT @airola_lab: Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, D…
Our collaborative study with @Rachid_Thiam, John Burke, & Peter Borbat now out in @NatureComms. Congrats to @yongmi88514, Dalila Ajjaji, and all authors Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation https://t.co/NtbbW6yLXm
(Nature MS) Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation (RSS) #nature #MassSpec https://t.co/J3pgqBmbHV https://t.co/Zp8T1yOpYW
RT @airola_lab: if you're at the #deuel conference make sure to check out Yong Mi's poster on perilipin 3 membrane association! if you're…
if you're at the #deuel conference make sure to check out Yong Mi's poster on perilipin 3 membrane association! if you're not, check out the preprint: Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation https://t.co/IjsUFaHpdF https://t.co/bodf5bnFn8