November 2023 PMID 38076795

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP.

Andrew Leduc, Luke Koury, Joshua Cantlon, Nikolai Slavov

Mentions

23
Peak: 7 in Nov 2023
across 5 sources since Nov 2023

Extended reach

18,651
potential audience

Total likes

58

Video views

3,444

Mentions per month

Nov 2023 – Nov 2025

Where it's discussed

  • X / Twitter8 posts
  • YouTube7 videos
  • Bluesky4 posts
  • News2 articles
  • Blogs2 articles

AI synopsis

What people are saying

The discussions collectively praise the publication for its innovative approach to single-cell proteomics, with posts emphasizing the method's scalability, speed, and use of common lab materials. For example, users refer to the study as a 'preprint of great significance' and highlight specific figures, demonstrating both enthusiasm and detailed engagement that underscore its potential to transform proteomics research.

AgreementModerate agreement

Most discussions express strong support or positive acknowledgment of the study, highlighting its significance in the field.

InterestHigh interest

The topic clearly piques interest, with multiple posts emphasizing enthusiasm for the technical advancements.

EngagementModerate engagement

Posts often reference specific figures like 'figure 5' or methodologies such as 'plexDIA,' indicating moderate but active engagement.

ImpactHigh impact

Many comments describe the method as a 'game changer' or 'significant,' reflecting perceived high impact on proteomics research.

Abstract in brief

  • nPOP is a high-throughput method that allows the preparation of thousands of single-cell samples in tiny droplets on glass slides, making single-cell proteomics faster and more scalable.
  • It uses mass spectrometry, specifically plexDIA, to accurately measure around 3000 to 3700 proteins per human cell, with the whole process taking only 1 or 2 days for over 3000 cells.
  • The protocol is flexible, utilizes common lab materials, and includes quality control tools, making it easier for labs to adopt and expand for large-scale single-cell protein analysis.]

Top posts

Most liked on X and Bluesky
Pastel BioScience
@PastelBio · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/FrVTNiCKGb --- #proteomics #prot-paper https://t.co/PXJE5eDnby

Aug 10, 2024 · 6 likes · 5,375 followers View post →
Pastel BioScience
@PastelBio · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/dRljOR5m3g --- #proteomics #prot-preprint https://t.co/GBhisslTel

Nov 29, 2023 · 4 likes · 1 share · 5,375 followers View post →
Geming (Brian) Lu
@Brian74534732 · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP. https://t.co/u4cMhLv8ga

Dec 16, 2023 · 3 likes · 724 followers View post →
MD BABU MIA, PHD
@BabuuDx · X

Great preprint of "Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP" from @slavovLab Look at the figure 5! https://t.co/JYGRzKDR7S

Nov 28, 2023 · 3 likes · 476 followers View post →
PastelBio
@pastelbio.bsky.social · Bluesky

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP www.biorxiv.org/cont... --- #proteomics #prot-preprint

Nov 29, 2023 · 2 likes · 1 share View post →
J of Mass Spec & Advances in the Clinical Lab
@JMSACL · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/hjHMUQpBQc

Dec 11, 2023 · 1 like · 1,009 followers View post →

All mentions

PastelBio
@pastelbio.bsky.social · Bluesky

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP www.nature.com/artic... --- #proteomics #prot-paper

Aug 10, 2024 View post →
Pastel BioScience
@PastelBio · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/FrVTNiCKGb --- #proteomics #prot-paper https://t.co/PXJE5eDnby

Aug 10, 2024 · 6 likes · 5,375 followers View post →
Kermit Murray
@kermitmurray · X

(BioRxiv All) Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/hlVkSFLjKY (RSS) #BioRxiv #MassSpecRSS https://t.co/UIVbKW7Rzm

Dec 21, 2023 · 1,969 followers View post →
Geming (Brian) Lu
@Brian74534732 · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP. https://t.co/u4cMhLv8ga

Dec 16, 2023 · 3 likes · 724 followers View post →
J of Mass Spec & Advances in the Clinical Lab
@JMSACL · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/hjHMUQpBQc

Dec 11, 2023 · 1 like · 1,009 followers View post →
Mass-spec@RIKEN BDR KOBE
@bdr_massspec · X

RT @PastelBio: Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/dRljOR5m3g --- #proteo…

Nov 29, 2023 · 1 share · 68 followers View post →
PastelBio
@pastelbio.bsky.social · Bluesky

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP www.biorxiv.org/cont... --- #proteomics #prot-preprint

Nov 29, 2023 · 2 likes · 1 share View post →
Pastel BioScience
@PastelBio · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/dRljOR5m3g --- #proteomics #prot-preprint https://t.co/GBhisslTel

Nov 29, 2023 · 4 likes · 1 share · 5,375 followers View post →
MD BABU MIA, PHD
@BabuuDx · X

Great preprint of "Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP" from @slavovLab Look at the figure 5! https://t.co/JYGRzKDR7S

Nov 28, 2023 · 3 likes · 476 followers View post →
bioRxiv Bioengineering
@bioRxiv_bioE · X

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://t.co/r0NF8dCQgW #biorxiv_bioE

Nov 28, 2023 · 206 followers View post →
bioRxiv Bioengineering
@biorxiv-bioeng.bsky.social · Bluesky

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://www.biorxiv.org/content/10.1101/2023.11.27.568927v1

Nov 28, 2023 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP https://www.biorxiv.org/content/10.1101/2023.11.27.568927v1

Nov 28, 2023 View post →