bioRxiv July 2024 PMID 39091738

Limiting the impact of protein leakage in single-cell proteomics.

Andrew Leduc, Yanxin Xu, Gergana Shipkovenska, Zhixun Dou, Nikolai Slavov

Mentions

15
Peak: 11 in Jul 2024
across 3 sources since Jul 2024

Extended reach

50,990
potential audience

Total likes

45

Video views

1,350

Mentions per month

Jul 2024 – May 2025

Where it's discussed

  • X / Twitter10 posts
  • Bluesky3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a positive reception, with mentions of artifacts, presentation of methods, and potential improvements, evidenced by phrases like 'reducing influence' and 'methods to improve data quality.' The tone is technically focused yet acknowledges the significance of advancing research in this field, which supports the high impact score.

AgreementModerate agreement

Most discussions acknowledge the significance of the publication's focus on reducing protein leakage artifacts, indicating general support.

InterestModerate interest

The posts express curiosity and appreciation for the research, especially with mentions of upcoming defenses and methods, reflecting moderate interest.

EngagementModerate engagement

Posts include references to experimental and computational approaches, with some sharing specific insights, showing active engagement.

ImpactHigh impact

The discussions highlight the importance of improving data accuracy, emphasizing that this research could greatly influence single-cell proteomics.

Abstract in brief

  • The study focuses on reducing protein leakage artifacts in single-cell proteomics to improve data quality, analyzing cells prepared fresh or after cryopreservation.
  • Researchers identify a signature of protein leakage by examining permeabilized cells, enabling them to classify and detect damaged cells.
  • The leakage detection method is effective across various cell types and species, helping ensure more accurate proteomic analysis.]

Top posts

Most liked on X and Bluesky
Slavov Laboratory
@slavovLab · X

Next week, @shiri_tsour and @_AndrewLeduc will be defending their dissertations ! They will present research from: https://t.co/dObDKJ85EJ https://t.co/gyIhKSKRi8 https://t.co/hpnd38VDE1 https://t.co/7nqZfGAsZ7 and more

Sep 10, 2024 · 16 likes · 1 share · 2,853 followers View post →
Prof. Nikolai Slavov
@slavov_n · X

Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein leakage during sample preparation for single-cell proteomics. To reduce their influence, we suggest experimental & computational methods. The good ... https://t.co/gZigkYsadb https://t.co/zvZFwdf98b

Jul 28, 2024 · 12 likes · 5 shares · 20,075 followers View post →
Prof. Nikolai Slavov
@slavov_n · X

RT @slavovLab: Next week, @shiri_tsour and @_AndrewLeduc will be defending their dissertations ! They will present research from: https:…

Sep 10, 2024 · 1 share · 20,075 followers View post →
Jamie Timmons
@metapredict · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 2,056 followers View post →
Vitalii Kleshchevnikov, PhD
@vitaliikl · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 1,797 followers View post →
Scott Tyler (@ScienceScottT@genomic.social)
@ScienceScottT · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 1,351 followers View post →

All mentions

PastelBio
@pastelbio.bsky.social · Bluesky

Limiting the impact of protein leakage in single-cell proteomics www.nature.com/artic... --- #proteomics #prot-paper

May 6, 2025 View post →
Prof. Nikolai Slavov
@slavov_n · X

RT @slavovLab: Next week, @shiri_tsour and @_AndrewLeduc will be defending their dissertations ! They will present research from: https:…

Sep 10, 2024 · 1 share · 20,075 followers View post →
Slavov Laboratory
@slavovLab · X

Next week, @shiri_tsour and @_AndrewLeduc will be defending their dissertations ! They will present research from: https://t.co/dObDKJ85EJ https://t.co/gyIhKSKRi8 https://t.co/hpnd38VDE1 https://t.co/7nqZfGAsZ7 and more

Sep 10, 2024 · 16 likes · 1 share · 2,853 followers View post →
david
@Minde_DavidPaul · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 65 followers View post →
Scott Tyler (@ScienceScottT@genomic.social)
@ScienceScottT · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 1,351 followers View post →
Vitalii Kleshchevnikov, PhD
@vitaliikl · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 1,797 followers View post →
Jamie Timmons
@metapredict · X

RT @slavov_n: Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein…

Jul 28, 2024 · 5 shares · 2,056 followers View post →
Prof. Nikolai Slavov
@slavov_n · X

Limiting the impact of protein leakage in single-cell proteomics. @_AndrewLeduc observed artifacts that we traced to protein leakage during sample preparation for single-cell proteomics. To reduce their influence, we suggest experimental & computational methods. The good ... https://t.co/gZigkYsadb https://t.co/zvZFwdf98b

Jul 28, 2024 · 12 likes · 5 shares · 20,075 followers View post →
Pooled Sequencing
@pooledseq · X

bioArXiv_ Limiting the impact of protein leakage in single-cell proteomics https://t.co/7C67M6HsoP

Jul 27, 2024 · 419 followers View post →
SciencesNetwork
@SciencesNetwork · X

Limiting the impact of protein leakage in single-cell proteomics https://t.co/n9sJJ3HX27

Jul 27, 2024 · 345 followers View post →
bioRxiv Molecular Biology
@biorxiv-molbio.bsky.social · Bluesky

Limiting the impact of protein leakage in single-cell proteomics https://www.biorxiv.org/content/10.1101/2024.07.26.605378v1

Jul 27, 2024 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Limiting the impact of protein leakage in single-cell proteomics https://www.biorxiv.org/content/10.1101/2024.07.26.605378v1

Jul 27, 2024 View post →
bioRxiv Molecular Biology
@biorxiv_molbio · X

Limiting the impact of protein leakage in single-cell proteomics https://t.co/xNNSvWW8EI #biorxiv_molbio

Jul 27, 2024 · 550 followers View post →