Front Sports Act Living August 2024 PMID 39205815

Give it a rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy.

Alec Singer, Milo Wolf, Leonardo Generoso, Elizabeth Arias, Kenneth Delcastillo, Edwin Echevarria, Amaris Martinez, Patroklos Androulakis Korakakis, Martin C Refalo, Paul A Swinton, Brad J Schoenfeld

Mentions

86
Peak: 64 in Aug 2024
across 4 sources since Apr 2024

Extended reach

590,610
potential audience

Total likes

7,003

Video views

234,254

Mentions per month

Apr 2024 – Jan 2026

Where it's discussed

  • X / Twitter76 posts
  • News6 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The discussions reflect a balanced view, with many posts discussing how the review supports shorter rest periods for hypertrophy, using phrases like 'modest negative effect' and 'more gains,' which convey both support and nuance. Additionally, some posts emphasize the complexity of the topic, indicating thoughtful engagement and recognition of practical implications.

AgreementModerate agreement

Most discussions acknowledge the findings, especially that shorter rest times may slightly hinder hypertrophy, showing general support.

InterestModerate interest

Posts show moderate interest, with some focusing on practical recommendations and individualization, indicating active engagement but not extreme curiosity.

EngagementModerate engagement

Participants reference specific research details, such as rest durations and effects on muscle growth, reflecting meaningful engagement.

ImpactModerate impact

The social discussions highlight how the review could influence training practices and future research directions, indicating a moderate impact.

Abstract in brief

  • This systematic review and Bayesian meta-analysis examined how different rest interval durations between sets affect muscle growth, using data from studies that controlled most training variables and measured muscle gains in healthy adults.
  • The results showed some evidence that shorter rest periods (around 60 seconds) might promote slightly more muscle hypertrophy, especially in the arms and thighs, possibly due to reduced volume load, but differences were small and varied across studies.
  • Rest intervals longer than about 90 seconds did not show significant additional benefits, suggesting that extending rest beyond this point doesn't further enhance muscle growth, as the negative effects on training volume tend to stabilize.

Top posts

Most liked on X and Bluesky
Brad Schoenfeld, PhD
@BradSchoenfeld · X

Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very short rest (~1 min); above 90 secs, no appreciable differences https://t.co/2kvEtTsAkT

Aug 2, 2024 · 333 likes · 45 shares · 95,680 followers View post →
Daniel Berglind, PhD
@DanielBerglind · X

Systematic review: More rest between set = more gains

Aug 22, 2024 · 67 likes · 15 shares · 7,849 followers View post →
Brad Schoenfeld, PhD
@BradSchoenfeld · X

@ActivateGlutes @adamcvscott @Guadango @jake_tuura @MarkBennett07 Actually, very short rest periods (~1 min or less) appear to blunt hypertrophy https://t.co/jJYNaiEDVe

Dec 27, 2024 · 5 likes · 95,680 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/rSMlGQWZu2

Aug 26, 2024 · 3 likes · 1 share · 4,255 followers View post →
Michael Tiger
@tiga_style · X

How long should you rest during training? It depends on your goal. For muscle growth, resting at least 60 seconds works best. Personally, I use a timer as a guide, but I always listen to my body—resting just enough to properly execute the next set. https://t.co/pLvm1NxKy1

Sep 10, 2024 · 3 likes · 1 share · 1,433 followers View post →
Nick Krontiris
@nick_krontiris · X

Give it a rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy (open access) https://t.co/WMyl87KEK0

Aug 14, 2024 · 2 likes · 19,387 followers View post →

All mentions

FungibleEther
@FungibleEther · X

@DeanTTraining While I agree, this is a meta analysis of the literature. So they are pointing towards lower rest times across many studies. Granted we need to take in ecological validity, but it is a pretty strong finding. https://t.co/Y5lcJWzo9L

Jun 5, 2025 · 1 like · 83 followers View post →
FungibleEther
@FungibleEther · X

@DeanTTraining This is a really complicated topic and a recent meta analysis shows that rest times really depend on many factors and may be individualized event to muscle groups. I am curious to see how the research unfolds in this area. https://t.co/Y5lcJWyQkd

May 17, 2025 · 1 like · 83 followers View post →
ユウキ/トレーナー×理学療法士×肉焼店長
@xqkk5s5FxE89350 · X

May 2, 2025 · 36 followers View post →
Dr. Grayson Wickham
@drgraysonDPT · X

[9/9] Rest duration between lifts references: https://t.co/e3cBKasfVx https://t.co/jrWh3x9sLh https://t.co/XCAmWhk9Xm https://t.co/XddZFjtDRw? https://t.co/XddZFjtDRw? https://t.co/2ujHRzx1a9 https://t.co/8kvxcyYnq2

Feb 18, 2025 · 449 followers View post →
Brad Schoenfeld, PhD
@BradSchoenfeld · X

@ActivateGlutes @adamcvscott @Guadango @jake_tuura @MarkBennett07 Actually, very short rest periods (~1 min or less) appear to blunt hypertrophy https://t.co/jJYNaiEDVe

Dec 27, 2024 · 5 likes · 95,680 followers View post →
Haresh Suppiah
@hareshsuppiah · X

Oct 24, 2024 · 2,080 followers View post →
Héctor Hernández
@hectorhernzfit · X

Referencia: https://t.co/hcDMa88bo0

Sep 15, 2024 · 2 likes · 2,669 followers View post →
Tiger Resilience LLC
@Tigeresilience · X

RT @tiga_style: How long should you rest during training? It depends on your goal. For muscle growth, resting at least 60 seconds works b…

Sep 10, 2024 · 1 share · 128 followers View post →
Michael Tiger
@tiga_style · X

How long should you rest during training? It depends on your goal. For muscle growth, resting at least 60 seconds works best. Personally, I use a timer as a guide, but I always listen to my body—resting just enough to properly execute the next set. https://t.co/pLvm1NxKy1

Sep 10, 2024 · 3 likes · 1 share · 1,433 followers View post →
比嘉一雄/筋肉まわりの全て/ヒガトレ®︎/AI 筋トレマシン Higatrec®
@Higa_Kazuo · X

休息時間の長さが筋肥大に与える影響は限定的。 60秒は休んだ方がよさそうだが、120秒以上はほぼ変わらない。 https://t.co/DNUKLrBSRH

Sep 2, 2024 · 1 like · 1,650 followers View post →
Danilo Amorim
@danilonutripers · X

RT @tecoughlin: Reference: https://t.co/rSMlGQWZu2

Aug 27, 2024 · 1 share · 104 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/rSMlGQWZu2

Aug 26, 2024 · 3 likes · 1 share · 4,255 followers View post →
ivanpinzon
@ivanpin81236291 · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 23, 2024 · 15 shares · 58 followers View post →
Slawomir
@Slawomi18369321 · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 23, 2024 · 15 shares · 85 followers View post →
Kinetic Impact
@KineticImpactRP · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 23, 2024 · 15 shares · 154 followers View post →
Gabriel Pérez
@gperez441 · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 284 followers View post →
Carlos Alberto
@CarlosAbertoVM · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 142 followers View post →
Joe Collins
@JD_Collins7 · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 341 followers View post →
Koushik
@koushikphysio · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 523 followers View post →
Adrián De la Rosa G.
@AdrianDeGonz · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 172 followers View post →
Anan
@Anan83174H · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 32 followers View post →
Ideefixe - Ιντεφίξ
@idefix_ideefixe · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 13 followers View post →
Liza Stathokostas, PhD
@ActiveAgingJnx · X

Review provides new direction for inter-set rest interval duration for muscle hypertrophy. Hypertrophy can be achieved across wide spectrum of rest interval w/ small benefit to employing longer vs. shorter inter-set rest intervals. https://t.co/GxCsIrFAso

Aug 22, 2024 · 1 like · 981 followers View post →
Mind Your Science!
@MindYourSci · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 132 followers View post →
Fundación Iberoamericana de Nutrición
@FinutOrg · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 4,047 followers View post →
Bensther DF
@BenstherDf · X

RT @DanielBerglind: Systematic review: More rest between set = more gains

Aug 22, 2024 · 15 shares · 143 followers View post →
Daniel Berglind, PhD
@DanielBerglind · X

Systematic review: More rest between set = more gains

Aug 22, 2024 · 67 likes · 15 shares · 7,849 followers View post →
s_vahid hosseini
@s_vahidhosseini · X

Is it time to reconsider the prescribed rest duration between sets for muscle hypertrophy? @BradSchoenfeld https://t.co/1uy7Me9DYh

Aug 21, 2024 · 86 followers View post →
Ale Moraes
@AleHartley · X

https://t.co/ZUvFbZF1UF

Aug 15, 2024 · 19 followers View post →
Frontiers - Sports and Active Living
@FrontSportsAL · X

New Research: Give it a rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy https://t.co/ivTp5hWr0O #FrontiersIn #SportsActiveLiving

Aug 14, 2024 · 4,167 followers View post →
Nick Krontiris
@nick_krontiris · X

Give it a rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy (open access) https://t.co/WMyl87KEK0

Aug 14, 2024 · 2 likes · 19,387 followers View post →
Ilustre Kefas
@Esperanza_Mex · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 10, 2024 · 45 shares · 796 followers View post →
Mind Your Science!
@MindYourSci · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 5, 2024 · 45 shares · 132 followers View post →
José Antonio Benítez Muñoz
@jabenitezm4 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 5, 2024 · 45 shares · 435 followers View post →
Mahito L'apostolos
@OMaMihai · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 4, 2024 · 45 shares · 306 followers View post →
Raúl Celdrán
@NTSAcademia · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 4, 2024 · 45 shares · 3,088 followers View post →
Footnotes of History
@curious_ledger · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 4, 2024 · 45 shares · 981 followers View post →
PA
@perfathletix · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 802 followers View post →
Carrie Mullin Innes
@scorenutrition · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 118 followers View post →
Incremental_Logic
@Incrementallog1 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 4,641 followers View post →
John Kenneth
@walkinginparis · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 1,412 followers View post →
William Amaral
@_sempreguica · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 122 followers View post →
Rosalie Brown
@rosaliebrownfit · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 1,931 followers View post →
s_vahid hosseini
@s_vahidhosseini · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 86 followers View post →
Thomas [Everyone is Satoshi. Except CSW]
@zoogydoogy · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 487 followers View post →
Kristopher Mendes de Souza
@KristopherDoc · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 66 followers View post →
Camille Goddard
@camillegoddard · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 137 followers View post →
Argón
@metilargon · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 352 followers View post →
Roger Hilfiker
@RogerHilfiker · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 1,618 followers View post →
Rodney Kennedy
@Rodn3yK3nn3dy · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 181 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 5,357 followers View post →
Oliver Faude
@OliverFaude · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 1,965 followers View post →
Pantelis Αngelides
@pantangelides · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 931 followers View post →
Tío Terrón
@AriesTerron · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 26,064 followers View post →
gio de biase
@gio1974db · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 462 followers View post →
Rx Readmore Livemore
@SopitaSirirata1 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 174 followers View post →
Thryve | Stress & Wellness
@ReallyThryve · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 314 followers View post →
Mean & Lean Fitness
@MeanLeanFitness · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 3, 2024 · 45 shares · 642 followers View post →
Prof. Nasser Alzerwi
@NAlzerwi · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 1,736 followers View post →
Jay Bert
@bert695 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 873 followers View post →
MarcoAntonioMedeiros
@professormarcoa · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 711 followers View post →
Raul
@RaulM06 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 851 followers View post →
Zack
@keychupkicap · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 389 followers View post →
Leonardo Amorim, MSc
@leonardo_amr · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 48 followers View post →
Daniel Godeassi
@dangodeassi · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 204 followers View post →
Dr Paul Swinton
@PaulSwinton9 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 451 followers View post →
Wil Martínez, entrenador
@Wilentrenador · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 130 followers View post →
Jeff A ⚜️
@JeffA000 · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 129 followers View post →
Mikey
@GaintrustMikey · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 32,661 followers View post →
-
@AlanMG__ · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 57 followers View post →
Dr Chris Kirk
@ChrisKirk_ASP · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 2,780 followers View post →
gx
@Gxrawr · X

RT @BradSchoenfeld: Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very sh…

Aug 2, 2024 · 45 shares · 43 followers View post →
Brad Schoenfeld, PhD
@BradSchoenfeld · X

Our meta-analysis on the effect of rest intervals on hypertrophy officially pubbed. Modest negative effect with very short rest (~1 min); above 90 secs, no appreciable differences https://t.co/2kvEtTsAkT

Aug 2, 2024 · 333 likes · 45 shares · 95,680 followers View post →
Nick Vardavas
@vardavas · X

1. Singer, Alec et al. (2024). Give it a Rest: A systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy. 10.51224/SRXIV.395.

Jun 12, 2024 · 134 followers View post →
Lorenzo S.Wayne
@LorenzoSWayne · X

Give it a Rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy

Apr 15, 2024 · 1 like · 51 followers View post →
javierbutra
@javierbutra · X

Give it a Rest A systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy https://t.co/QtEb4u3n2a https://t.co/YOvgmIrh5k

Apr 15, 2024 · 1 like · 14,356 followers View post →