Nature July 2025 PMID 40267983

Geographic and age variations in mutational processes in colorectal cancer.

Marcos Díaz-Gay, Wellington Dos Santos, Sarah Moody, Mariya Kazachkova, Ammal Abbasi, Christopher D Steele, Raviteja Vangara, Sergey Senkin, Jingwei Wang, Stephen Fitzgerald, Erik N Bergstrom, Azhar Khandekar, Burçak Otlu, Behnoush Abedi-Ardekani, Ana Carolina de Carvalho

Mentions

474
Peak: 57 in Apr 2025
across 7 sources since Apr 2025

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1,240,015
potential audience

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788

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AI synopsis

What people are saying

Many discussions highlight the connection between early-life exposure to the bacteria colibactin and rising rates of colorectal cancer, with users using terms like 'game changer' and 'critical issue' to describe its consequences. Phrasing such as 'new insights into mutation processes' and 'needs urgent attention' suggests that the choice of words and passionate tone significantly enhance the overall urgency and importance that the community places on this research.

AgreementModerate agreement

Most discussions show a moderate to strong support for the findings, indicating a general consensus about the relevance of the research.

InterestHigh interest

There is high curiosity surrounding the publication, with many users expressing interest in its implications and findings.

EngagementModerate engagement

Many posts reference specific aspects of the study, such as the mutagen colibactin, but some appear more casual in their commentary.

ImpactHigh impact

Participants generally believe that the publication has significant implications for understanding colorectal cancer incidence.

Abstract in brief

  • Incidence rates of colorectal cancer vary across regions and have increased, particularly for early-onset cases in individuals under 50, which have doubled in the last 20 years.
  • The study examined colorectal cancer genomes from 11 countries, revealing no major differences in unstable cancers but noted varying mutation burdens and patterns, especially in microsatellite-stable cases.
  • A specific mutagen produced by bacteria (colibactin) was associated with higher mutation loads in countries with increased colorectal cancer rates and was significantly linked to early-onset cases, suggesting that early life exposure to this mutagen might be a factor in the rising incidence.

Top posts

Most liked on X and Bluesky
はじめまして 平岡です
@HiraokaYasushi · X

原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C 国内大腸がん、5割が細菌原因か 毒素で変異、若年発症増に関係も(共同通信) https://t.co/VHqY7KYGG9

May 21, 2025 · 97 likes · 9 shares · 6,204 followers View post →
いっちー@バーチャル精神科医
@ichiipsy · X

コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes in colorectal cancer. Nature https://t.co/WxBcj7Kw58

Apr 30, 2025 · 27 likes · 5 shares · 79,323 followers View post →
IARC
@IARCWHO · X

New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer risk decades later, especially in those under 50. Unique mutational patterns across regions stress the need for tailored prevention: https://t.co/mLtg4LrEID

Apr 25, 2025 · 19 likes · 11 shares · 17,648 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hyKch #オープンアクセス @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/14XkZac0k6

Jul 6, 2025 · 14 likes · 5 shares · 91,363 followers View post →
音良 林太郎, MD, PhD
@Otola_ryntaro · X

こちら原文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/vB9I8UEWjW

May 21, 2025 · 12 likes · 15,668 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hyKch 閲覧用リンク:https://t.co/lox5NQDArX @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/D4Ftij6LJE

May 30, 2025 · 10 likes · 3 shares · 91,363 followers View post →

All mentions

bioZone
@thebiozone · X

information sources: +Rebecca Siegel et al. (2020). https://t.co/eUvb5f5Rqp +Christina Bailey et al. (2015). https://t.co/ZgedsO3JXI +Marcos Díaz-Gay et al. (2025). https://t.co/6V9GF22QA3 +Axel Rosendahl Huber et al. (2024). https://t.co/TmA2QRtFo2

Aug 31, 2025 · 186 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/8uQSA9VDtm

Aug 17, 2025 · 1 share · 3,153 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/8uQSA9VDtm

Aug 17, 2025 · 1 share · 3,153 followers View post →
Sandra kate
@sshanmugamgens1 · X

RT @ekocakavuk: Geographic and age variations in mutational processes in colorectal cancer | ⁦@Nature⁩ https://t.co/luMeKc3cPn

Aug 7, 2025 · 1 share · 862 followers View post →
Framin Sigy
@FraminSigy · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jul 8, 2025 · 5 shares · 204 followers View post →
Springer Healthplus JP
@shc_jp · X

大腸がんの変異過程における地理的および年齢による差異 Geographic and age variations in mutational processes in colorectal cancer https://t.co/W9BeD6Xeh6 #Nature誌 #大腸がん #全ゲノム解析 #コリバクチン毒素 #国際共同研究 #国立がん研究センター https://t.co/apTnlwnIiw

Jul 7, 2025 · 587 followers View post →
Atsuya Nishiyama
@NishiyamaAtsuya · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jul 7, 2025 · 5 shares · 679 followers View post →
Noriko Gotoh
@GotohNoriko · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jul 7, 2025 · 5 shares · 150 followers View post →
Takashi Kohno@Natl Cancer Ctr, Japan
@TakashiKohno2 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jul 7, 2025 · 5 shares · 601 followers View post →
竹内 康正 ❤️ Yasumasa Takeuchi
@zephyorg · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jul 7, 2025 · 5 shares · 6,309 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hyKch #オープンアクセス @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/14XkZac0k6

Jul 6, 2025 · 14 likes · 5 shares · 91,363 followers View post →
Alex Chudnovskiy
@ChudnovskiyLab · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/71TzrHutQO

Jul 6, 2025 · 1 like · 838 followers View post →
Sara Gutiérrez-Enríquez
@SaraGutierrezEn · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/rPEDoAB8Fu

Jul 4, 2025 · 3 likes · 725 followers View post →
kai
@kai958531911 · X

大腸がんの変異過程における地理的および年齢的変動 Geographic and age variations in mutational processes in colorectal cancer https://t.co/ISFz15onGT

Jun 27, 2025 · 265 followers View post →
tatsunori_shimoi 下井辰徳
@shimoi_oncology · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jun 20, 2025 · 3 shares · 1,408 followers View post →
Takashi Kohno@Natl Cancer Ctr, Japan
@TakashiKohno2 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jun 20, 2025 · 3 shares · 601 followers View post →
カオナシ(T. MATSUMOTO)
@CharStream · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

Jun 19, 2025 · 3 shares · 549 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hyKch #オープンアクセス @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/uz5IJ95CQF

Jun 19, 2025 · 4 likes · 3 shares · 91,363 followers View post →
yumi @gj
@ygjumi · X

RT @ygjumi: Geographic and age variations in mutational processes in colorectal cancer https://t.co/WX7iiDR5OJ

Jun 7, 2025 · 1 share · 12,773 followers View post →
フルチン中年男性
@otakutokkai · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in colo…

May 30, 2025 · 3 shares · 1,652 followers View post →
SAKAKIBARA Yoji
@sakak.bsky.social · Bluesky

Geographic and age variations in mutational processes in colorectal cancer | Nature www.nature.com/articles/s41...

May 30, 2025 View post →
SAKAKIBARA Yoji
@sakak · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in colo…

May 30, 2025 · 3 shares · 540 followers View post →
ryugo hayano
@hayano · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in colo…

May 30, 2025 · 3 shares · 117,522 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hyKch 閲覧用リンク:https://t.co/lox5NQDArX @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/D4Ftij6LJE

May 30, 2025 · 10 likes · 3 shares · 91,363 followers View post →
yumi @gj
@ygjumi · X

Geographic and age variations in mutational processes in colorectal cancer https://t.co/WX7iiDR5OJ

May 30, 2025 · 1 like · 1 share · 12,773 followers View post →
とこちゃん
@kasokukitearoom · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

May 30, 2025 · 6 shares · 2,246 followers View post →
フルチン中年男性
@otakutokkai · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

May 30, 2025 · 6 shares · 1,652 followers View post →
らどん
@radon12345 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

May 30, 2025 · 6 shares · 2,074 followers View post →
カオナシ(T. MATSUMOTO)
@CharStream · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

May 30, 2025 · 6 shares · 549 followers View post →
ryugo hayano
@hayano · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

May 30, 2025 · 6 shares · 117,522 followers View post →
blue
@__b__l__u__e___ · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in…

May 29, 2025 · 6 shares · 62 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov 氏らの #大腸がん における変異に関する@Nature #OA #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hyKch #オープンアクセス @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/UrKn1vb3xy

May 29, 2025 · 9 likes · 6 shares · 91,363 followers View post →
WinAlly
@WinAlly_com · X

Geographic and age variations in mutational processes in colorectal cancer #KolonKanseri #Colibactin #Kanser #Winally https://t.co/xzAogbYMz6

May 28, 2025 · 860 followers View post →
whiterabit_0330
@whiterabit_0330 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in color…

May 26, 2025 · 5 shares · 47 followers View post →
StillerNP
@LogosFNP · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/Q26n1Fq8Xp

May 25, 2025 · 1 like · 34 followers View post →
腸内細菌相談室
@chonai_saikin · X

参考文献

May 23, 2025 · 2 likes · 462 followers View post →
あお
@suirin_s · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in color…

May 23, 2025 · 5 shares · 4 followers View post →
doa
@uroyo0000 · X

RT @HiraokaYasushi: 原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C…

May 22, 2025 · 9 shares · 29 followers View post →
坪田博美@飛ばない存在感の薄い在庫処分品殲滅隊長(非売品&見習い期間中)火星には辿り着けるはず
@chuboht · X

@Sankei_news Díaz-Gay, M., dos Santos, W., Moody, S. et al. Geographic and age variations in mutational processes in colorectal cancer. Nature (2025). https://t.co/crELIFK32z

May 22, 2025 · 1,746 followers View post →
ε(ミミ ๑・ิ 』・ิ๑ )
@edamame0811 · X

RT @HiraokaYasushi: 原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C…

May 22, 2025 · 9 shares · 949 followers View post →
Takashi Kohno@Natl Cancer Ctr, Japan
@TakashiKohno2 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in color…

May 22, 2025 · 5 shares · 601 followers View post →
TakeTam
@bic_icr_kyoto · X

RT @HiraokaYasushi: 原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C…

May 22, 2025 · 9 shares · 742 followers View post →
yumi @gj
@ygjumi · X

RT @ygjumi: Geographic and age variations in mutational processes in colorectal cancer https://t.co/WX7iiDR5OJ

May 22, 2025 · 1 share · 12,773 followers View post →
ト
@uet1 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in color…

May 22, 2025 · 5 shares · 683 followers View post →
山人(Yamato)
@Yamato41510 · X

RT @NatureJapan: 柴田 龍弘 氏、Ludmil B. Alexandrov氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in color…

May 22, 2025 · 5 shares · 63 followers View post →
Nature Japan
@NatureJapan · X

柴田 龍弘 氏、Ludmil B. Alexandrov氏らの #大腸がん における変異に関する@Nature #論文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/Z1Cc1hzi1P 閲覧用リンク:https://t.co/lox5NQE8hv @NccriOfficial @UTokyo_News @UCSanDiego https://t.co/bFieDVGUOT

May 22, 2025 · 6 likes · 5 shares · 91,363 followers View post →
MATSUMOTO Yutaka
@yutakama · X

RT @HiraokaYasushi: 原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C…

May 21, 2025 · 9 shares · 3,198 followers View post →
かなかにゃ?
@VMw6MoJTnwD9ePZ · X

23 April 2025

May 21, 2025 · 288 followers View post →
umptemp
@Umptemping · X

https://t.co/YuO7poT6cR

May 21, 2025 · 41 followers View post →
間宮健太郎/土野魔魅
@mami_tuchino · X

RT @ma31stm: Geographic and age variations in mutational processes in colorectal cancer. https://t.co/zm3bhs4TTG

May 21, 2025 · 1 share · 801 followers View post →
まつこ
@ma31stm · X

Geographic and age variations in mutational processes in colorectal cancer. https://t.co/zm3bhs4TTG https://t.co/IS3Bq3oKOw

May 21, 2025 · 1 like · 1 share · 2,248 followers View post →
vivian
@phoebe_vivian · X

RT @HiraokaYasushi: 原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C…

May 21, 2025 · 9 shares · 154 followers View post →
Takefumi Kimura
@VulletForMy · X

RT @HiraokaYasushi: 原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C…

May 21, 2025 · 9 shares · 167 followers View post →
はじめまして 平岡です
@HiraokaYasushi · X

原論文はこちら Nature 2025 Geographic and age variations in mutational processes in colorectal cancer https://t.co/nnnb1mob6C 国内大腸がん、5割が細菌原因か 毒素で変異、若年発症増に関係も(共同通信) https://t.co/VHqY7KYGG9

May 21, 2025 · 97 likes · 9 shares · 6,204 followers View post →
yumi @gj
@ygjumi · X

Geographic and age variations in mutational processes in colorectal cancer https://t.co/WX7iiDR5OJ

May 21, 2025 · 1 share · 12,773 followers View post →
音良 林太郎, MD, PhD
@Otola_ryntaro · X

こちら原文 Geographic and age variations in mutational processes in colorectal cancer https://t.co/vB9I8UEWjW

May 21, 2025 · 12 likes · 15,668 followers View post →
SASANO Takayoshi
@uaa.bsky.social · Bluesky

国際共同研究により大腸がんの全ゲノム解析を実施し日本人症例を解析 日本人大腸がん患者さんの5割に特徴的な腸内細菌による発がん要因を発見(2025/05/21) www.ncc.go.jp/jp/informati... にも記されているけど、 Geographic and age variations in mutational processes in colorectal cancer (2025/04/23) www.nature.com/articles/s41... が元ネタか。 bsky.app/profile/47ne...

May 21, 2025 · 1 like · 2 shares View post →
ささもてぃんⁿ@糖尿魔王
@yukihirosasamo · X

これか。 Geographic and age variations in mutational processes in colorectal cancer https://t.co/kzf4hcisyr https://t.co/zlFqnFsTA0

May 21, 2025 · 10 likes · 6,475 followers View post →
Equity & Health
@equitylist · X

RT @GlobalPHObserv: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

May 20, 2025 · 3 shares · 28,812 followers View post →
Lucia Ruggiero EALR
@luciaruggiero · X

RT @GlobalPHObserv: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

May 20, 2025 · 3 shares · 1,033 followers View post →
Culture of Health Eq
@CofHEQ · X

RT @GlobalPHObserv: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

May 20, 2025 · 3 shares · 1,094 followers View post →
Global Health Observ
@GlobalPHObserv · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

May 20, 2025 · 5 likes · 3 shares · 6,556 followers View post →
旅人 tabito
@tabibito250 · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/LLwTTYvnL2

May 9, 2025 · 1,075 followers View post →
旅人 tabito
@tabibito250 · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/LLwTTYvnL2

May 8, 2025 · 1,075 followers View post →
Reiner 
@erlesen · X

RT @erlesen: Geographic and age variations in mutational processes in colorectal cancer. Signatures SBS88 and ID18, caused by the bacteria-…

May 7, 2025 · 1 share · 7,867 followers View post →
Cáncer Granada
@CancerGranada · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

May 6, 2025 · 11 shares · 1,006 followers View post →
John West
@JohnWest_JAWS · X

RT @AndrewW66619812: The paper in "Nature" the above "Guardian" article is based upon, & links to: “Geographic and age variations in mutat…

May 1, 2025 · 1 share · 25,775 followers View post →
Andy_Weeble_Weaver
@AndrewW66619812 · X

The paper in "Nature" the above "Guardian" article is based upon, & links to: “Geographic and age variations in mutational processes in colorectal cancer” 2/2 https://t.co/iseigMSQC7

May 1, 2025 · 1 like · 1 share · 4,341 followers View post →
3200Kelvin
@3200K · X

RT @ichiipsy: コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes i…

May 1, 2025 · 5 shares · 437 followers View post →
Jeffry Beltre E.
@Mr_Jeffry · X

RT @DoctorHumber: El estudio de Díaz-Gay et al. (2025) publicado en Nature encontró que:

Apr 30, 2025 · 1 share · 2,044 followers View post →
Doctor Humber
@DoctorHumber · X

El estudio de Díaz-Gay et al. (2025) publicado en Nature encontró que:

Apr 30, 2025 · 4 likes · 1 share · 47,327 followers View post →
がたいがでかい
@gataigadekai · X

RT @ichiipsy: コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes i…

Apr 30, 2025 · 5 shares · 413 followers View post →
モエギ@慶應通信文1
@moegi_edu · X

RT @ichiipsy: コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes i…

Apr 30, 2025 · 5 shares · 729 followers View post →
仲町六絵_32冊目 12/18発売
@karakusashuzai · X

RT @ichiipsy: コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes i…

Apr 30, 2025 · 5 shares · 1,866 followers View post →
下條美智3
@BBE5151 · X

RT @ichiipsy: コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes i…

Apr 30, 2025 · 5 shares · 190 followers View post →
いっちー@バーチャル精神科医
@ichiipsy · X

コリバクチンを産生する菌を減らすには腸内環境を整えることが大切で、食物繊維や発酵食品を食べ、運動をして、禁煙や節酒を心がけることが重要。 Geographic and age variations in mutational processes in colorectal cancer. Nature https://t.co/WxBcj7Kw58

Apr 30, 2025 · 27 likes · 5 shares · 79,323 followers View post →
Paul Pharoah
@paulpharoah.bsky.social · Bluesky

... cause that became more prevalent and is now waning. Infection seems to be a good candidate for something that changes over time in this way. Colibactin producing E Coli one possibility. pubmed.ncbi.nlm.nih.gov/40267983/ 3/3

Apr 29, 2025 · 3 likes · 2 shares View post →
Nathan Goodyear, MD, MD(H)
@drgoodyear · X

Colorectal Cancer Is Changing—And It Might Start in Your Gut Supporting evidence: Díaz-Gay, M., dos Santos, W., Moody, S. et al.Geographic and age variations in mutational processes in colorectal cancer. Nature (2025). https://t.co/MTP7Q8qrE8 https://t.co/go1IjX3FkL

Apr 29, 2025 · 1,710 followers View post →
Reiner
@erlangen.bsky.social · Bluesky

Geographic and age variations in mutational processes in colorectal cancer. Signatures SBS88 and ID18, caused by the bacteria-produced mutagen colibactin www.nature.com/articles/s41... Gefahr im Essen: Bakterien könnten Darmkrebs bei Jüngeren auslösen www.t-online.de/gesundheit/a...

Apr 29, 2025 View post →
Reiner 
@erlesen · X

Geographic and age variations in mutational processes in colorectal cancer. Signatures SBS88 and ID18, caused by the bacteria-produced mutagen colibactin https://t.co/PGgYPYlg3L Gefahr im Essen: Bakterien könnten Darmkrebs bei Jüngeren auslösen https://t.co/HJ6OMRws4z

Apr 29, 2025 · 2 likes · 1 share · 7,867 followers View post →
Lino C M
@lcm69e · X

Geographic and age variations in mutational processes in colorectal cancer Díaz-Gay, M., dos Santos, W., Moody, S. et al. Geographic and age variations in mutational processes in colorectal cancer. Nature (2025). https://t.co/p0hlhKXvWH https://t.co/mQJrACux3h

Apr 27, 2025 · 868 followers View post →
Paul Brennan
@Lyonpaul · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 27, 2025 · 11 shares · 697 followers View post →
Eric Chevet
@ericchevet.bsky.social · Bluesky

Geographic and age variations in mutational processes in colorectal cancer www.nature.com/articles/s41...

Apr 26, 2025 · 4 likes · 1 share View post →
Joel Moskowitz
@berkeleyprc · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 26, 2025 · 11 shares · 2,906 followers View post →
Giota Mitrou
@DrPMitrou · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 1,984 followers View post →
maria jose sanchez
@mjsanchezperez · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 2,957 followers View post →
Dr.OscarPLTox
@DROPUELLO · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 114 followers View post →
Mariam Khan
@mariamibkhan · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 1,155 followers View post →
Claire Taylor
@claire_taylor22 · X

Early-life mutagenic exposure to 107 colibactin-producing bacteria may contribute to the rising incidence of early-onset colorectal Díaz-Gay, et al. Geographic & age variations in mutational processes in colorectal cancer. Nature (2025). https://t.co/hbLvXMLgCh

Apr 25, 2025 · 2 likes · 2,294 followers View post →
Garcia(de
@SargentoGarcia · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 856 followers View post →
thewholehealthlab
@TWHLofficial · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 15 followers View post →
Grace Young
@futurecellg · X

RT @IARCWHO: New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer ris…

Apr 25, 2025 · 11 shares · 15 followers View post →
IARC
@IARCWHO · X

New IARC study shows that early exposure to certain gut bacteria may trigger genetic changes, increasing #colorectalcancer risk decades later, especially in those under 50. Unique mutational patterns across regions stress the need for tailored prevention: https://t.co/mLtg4LrEID

Apr 25, 2025 · 19 likes · 11 shares · 17,648 followers View post →
Alice
@Yaya24632175707 · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/m5k3uKozr8

Apr 25, 2025 · 196 followers View post →
Dr. Máté
@milena_mate · X

RT @sangerinstitute: Read ‘Geographic and age variations in mutational processes in colorectal cancer’ from @UCSanDiego and @sangerinstitu…

Apr 24, 2025 · 1 share · 1,068 followers View post →
Tae Hoon Kim
@taehoonkim · X

Geographic and age variations in mutational processes in colorectal cancer https://t.co/DDSTGh3Jj2

Apr 24, 2025 · 788 followers View post →
Equity & Health
@equitylist · X

RT @GlobalPHObserv: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

Apr 24, 2025 · 3 shares · 28,812 followers View post →
Culture of Health Eq
@CofHEQ · X

RT @GlobalPHObserv: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

Apr 24, 2025 · 3 shares · 1,094 followers View post →
Manju George MVSc PhD Rectal Cancer Survivor
@manjuggm · X

RT @josepereag: Geographic and age-related variations in CRC mutational profiles, suggesting that early-life mutagenic exposure to colibact…

Apr 24, 2025 · 5 shares · 2,536 followers View post →
Roberta Horgan
@HorganRoberta · X

RT @josepereag: Geographic and age-related variations in CRC mutational profiles, suggesting that early-life mutagenic exposure to colibact…

Apr 24, 2025 · 5 shares · 2,621 followers View post →
lynch syndrome irl @lsireland.bsky.social
@Lynchsyndromirl · X

RT @josepereag: Geographic and age-related variations in CRC mutational profiles, suggesting that early-life mutagenic exposure to colibact…

Apr 24, 2025 · 5 shares · 2,403 followers View post →
Edward Robinson
@edwardlabs · X

RT @weldeiry: Geographic and age variations in mutational processes in colorectal cancer https://t.co/ZqrHRieNyB

Apr 24, 2025 · 1 share · 32 followers View post →
Mac Jamil
@mac_jamil · X

Geographic and age variations in mutational processes in colorectal cancer https://t.co/8DXE2mWZaJ

Apr 24, 2025 · 358 followers View post →
ColorectalResearch_ICH
@CResearchICH · X

RT @josepereag: Geographic and age-related variations in CRC mutational profiles, suggesting that early-life mutagenic exposure to colibact…

Apr 24, 2025 · 5 shares · 435 followers View post →
Fradi Frad Dreizehn
@frad_fradi · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/iESMP7D90r

Apr 24, 2025 · 2,455 followers View post →
Wellcome Sanger Institute
@sangerinstitute.bsky.social · Bluesky

Read ‘Geographic and age variations in mutational processes in colorectal cancer’ from @ucsandiego.bsky.social and @sangerinstitute.bsky.social and their collaborators in @nature.com, here: www.nature.com/articles/s41...

Apr 24, 2025 · 2 likes View post →
Wellcome Sanger Institute
@sangerinstitute · X

Read ‘Geographic and age variations in mutational processes in colorectal cancer’ from @UCSanDiego and @sangerinstitute and their collaborators in @Nature, here: https://t.co/2K6T585YH6

Apr 24, 2025 · 1 like · 1 share · 71,976 followers View post →
Emily Harrold
@EmilyHarrold6 · X

RT @josepereag: Geographic and age-related variations in CRC mutational profiles, suggesting that early-life mutagenic exposure to colibact…

Apr 24, 2025 · 5 shares · 626 followers View post →
JOSÉ PEREA GARCÍA
@josepereag · X

Geographic and age-related variations in CRC mutational profiles, suggesting that early-life mutagenic exposure to colibactin-producing bacteria may contribute to the rising of #EOCRC. The importance of exploring geographical disparities among #EOCRC. https://t.co/F9iijPZW5B

Apr 24, 2025 · 9 likes · 5 shares · 1,252 followers View post →
Bartomeu Colom
@bartomeucolom.bsky.social · Bluesky

'Geographic and age variations in mutational processes in colorectal cancer' www.nature.com/articles/s41...

Apr 24, 2025 View post →
Lucia Ruggiero EALR
@luciaruggiero · X

RT @GlobalPHObserv: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

Apr 24, 2025 · 3 shares · 1,033 followers View post →
Global Health Observ
@GlobalPHObserv · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/AQzmCx2U75

Apr 23, 2025 · 5 likes · 3 shares · 6,556 followers View post →
Lucia Ruggiero
@lruggiero.bsky.social · Bluesky

Geographic and age variations in mutational processes in colorectal cancer | Nature www.nature.com/articles/s41...

Apr 23, 2025 View post →
Sara Gutiérrez-Enríquez
@SaraGutierrezEn · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/rPEDoAAAPW

Apr 23, 2025 · 725 followers View post →
priya joseph
@ayirpelle · X

RT @hlcao: Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/wQp9f68b9T

Apr 23, 2025 · 1 share · 4,978 followers View post →
Huiluo Cao 曹慧荦
@hlcao · X

Geographic and age variations in mutational processes in colorectal cancer | Nature https://t.co/wQp9f68b9T

Apr 23, 2025 · 1 like · 1 share · 2,835 followers View post →
Paul Brennan
@Lyonpaul · X

RT @CancerGrand: Find the full paper, "Geographic and age variations in mutational processes in colorectal cancer", led by Ludmil Alexandro…

Apr 23, 2025 · 4 shares · 697 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social · Bluesky

Geographic and age variations in mutational processes in colorectal cancer www.nature.com/articles/s41...

Apr 23, 2025 · 1 like View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Geographic and age variations in mutational processes in colorectal cancer https://t.co/ZqrHRieNyB

Apr 23, 2025 · 3 likes · 1 share · 18,503 followers View post →
Raviteja Vangara
@VangaraRaviteja · X

RT @CancerGrand: Find the full paper, "Geographic and age variations in mutational processes in colorectal cancer", led by Ludmil Alexandro…

Apr 23, 2025 · 4 shares · 232 followers View post →
DaveChuter@OGcancersupport
@CancerOG · X

RT @CancerGrand: Find the full paper, "Geographic and age variations in mutational processes in colorectal cancer", led by Ludmil Alexandro…

Apr 23, 2025 · 4 shares · 512 followers View post →
Lorenzo de la Rica (he/him)
@LdelaRica · X

RT @CancerGrand: Find the full paper, "Geographic and age variations in mutational processes in colorectal cancer", led by Ludmil Alexandro…

Apr 23, 2025 · 4 shares · 776 followers View post →
Lorenzo de la Rica
@ldelarica.bsky.social · Bluesky

Find the full paper

Apr 23, 2025 View post →
Emre Kocakavuk, MD, PhD
@ekocakavuk · X

Geographic and age variations in mutational processes in colorectal cancer | ⁦@Nature⁩ https://t.co/luMeKc3cPn

Apr 23, 2025 · 4 likes · 1 share · 936 followers View post →
GMIK69BSKY
@gmik69bsky.bsky.social · Bluesky

#Geographic and #age #variations in mutational processes in #colorectal #cancer, etidiohnew.blogspot.com/2025/04/geog...

Apr 23, 2025 View post →
Cancer Grand Challenges
@CancerGrand · X

Find the full paper, "Geographic and age variations in mutational processes in colorectal cancer", led by Ludmil Alexandrov @UCSanDiego, here: https://t.co/og8OK3VjWo

Apr 23, 2025 · 6 likes · 4 shares · 5,232 followers View post →