PubHawk
October 2025 PMID 40888730

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension.

John M Flack, Michel Azizi, Jenifer M Brown, Jamie P Dwyer, Jakub Fronczek, Erika S W Jones, Daniel S Olsson, Shira Perl, Hirotaka Shibata, Ji-Guang Wang, Ulrica Wilderäng, Janet Wittes, Bryan Williams

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542
Peak: 104 in Oct 2025
across 6 sources since Aug 2025

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AI synopsis

What people are saying

Multiple discussions underscore the promising results of the BaxHTN trial, noting how baxdrostat significantly lowers systolic blood pressure in patients who do not respond to traditional treatments. Phrases like 'game changer' and 'promising new option' reflect a positive and urgent tone, showcasing a collective eagerness to see this treatment implemented in clinical settings.

AgreementStrong agreement

The majority of discussions express strong support for the findings on baxdrostat's effectiveness, indicating a high level of consensus on its potential benefits.

InterestHigh interest

Participants show significant curiosity and relevance, with many using enthusiastic language and showcasing interest in the implications of the research.

EngagementModerate engagement

While many users share information, the depth of engagement varies; most comments focus on summary statements rather than personal insights or in-depth analysis.

ImpactHigh impact

Several contributors highlight the potential positive implications of baxdrostat for treatment-resistant hypertension, suggesting they view it as an important breakthrough in cardiovascular care.

Abstract in brief

  • Baxdrostat is an aldosterone synthase inhibitor that has been shown to effectively reduce seated systolic blood pressure in patients with uncontrolled and resistant hypertension, highlighting its potential as a treatment option.
  • In a phase 3 clinical trial involving 796 patients, those treated with 1 mg and 2 mg doses of baxdrostat experienced significant reductions in blood pressure compared to placebo after 12 weeks of treatment.
  • While baxdrostat showed promising results, there were some safety concerns, including elevated potassium levels in a small number of patients, necessitating careful monitoring.
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NEJM
@NEJM · X

Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.co/iRVxdmp7Ss Editorial: Aldosterone Synthase Inhibition for Hypertension https://t.co/qAx3z4Iy7s #Cardiology https://t.co/lmQPkR8Na7

Oct 10, 2025 · 321 likes · 92 shares · 936,101 followers View post →
NEJM
@NEJM · X

In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therapy led to a lower seated systolic blood pressure than placebo at 12 weeks. Full trial results and Research Summary: https://t.co/iRVxdmp7Ss https://t.co/UWfk8wIufr

Oct 13, 2025 · 46 likes · 5 shares · 936,101 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resistant hypertension, the addition of baxdrostat to background therapy resulted in a significantly lower seated systolic blood pressure at 12 weeks than placebo. https://t.co/GfmsNRPEYt

Sep 17, 2025 · 41 likes · 10 shares · 2,774 followers View post →
Medical Xpress
@medical_xpress · X

An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-resistant #Hypertension, offering a promising new option for improved cardiovascular outcomes. @uclnews @nejm https://t.co/lbdwIi3zHg https://t.co/ZIfKg275zh

Aug 30, 2025 · 24 likes · 21 shares · 173,154 followers View post →
René Escamilla
@ReneScamilla9 · X

@96king_of_f @Nephro_Ivan @NEJM DOI:10.1056/NEJMoa2507109

Oct 13, 2025 · 6 likes · 1 share · 96 followers View post →
NEJM.org
@nejm.org · Bluesky

In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therapy led to a lower seated systolic blood pressure than placebo at 12 weeks. Full trial results and Research Summary: nej.md/4my7xUZ #MedSky #CardioSky

Oct 13, 2025 · 6 likes · 2 shares View post →

All mentions

STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Baxdrostat significantly lowers systolic blood pressure in patients with uncontrolled and resistant hypertension, outperforming placebo in a pivotal trial. by Flack JM, Azizi M (...) Williams B et 10 al. in N Engl J Med https://t.co/akwuBB5j2Z #MedX #MedResearch

Oct 18, 2025 · 88 followers View post →
H.
@parisianmedstud · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 17, 2025 · 92 shares · 18 followers View post →
Ivan Velázquez
@Nephro_Ivan · X

@mogalju @NEJM Published August 30, 2025 N Engl J Med 2025;393:1363-1374 DOI: 10.1056/NEJMoa2507109

Oct 16, 2025 · 2,441 followers View post →
Ilich
@TheNameless72 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 14, 2025 · 92 shares · 1 followers View post →
Med Peds Hospitalist
@medpedshosp · X

https://t.co/AsawU45npw https://t.co/zgCeUGiEeI

Oct 14, 2025 · 1 like · 14,243 followers View post →
Med Peds Hospitalist
@medpedshosp · X

@Nephro_Ivan @NEJM https://t.co/AsawU45npw

Oct 14, 2025 · 1 like · 14,243 followers View post →
Med Peds Hospitalist
@medpedshosp · X

@96king_of_f @Nephro_Ivan @NEJM https://t.co/AsawU45npw

Oct 14, 2025 · 3 likes · 14,243 followers View post →
esteban rengel
@estebanrengel · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 14, 2025 · 92 shares · 33 followers View post →
Victor Adrian
@adriaan00 · X

RT @ReneScamilla9: @96king_of_f @Nephro_Ivan @NEJM DOI:10.1056/NEJMoa2507109

Oct 14, 2025 · 1 share · 63 followers View post →
René Escamilla
@ReneScamilla9 · X

@96king_of_f @Nephro_Ivan @NEJM DOI:10.1056/NEJMoa2507109

Oct 13, 2025 · 6 likes · 1 share · 96 followers View post →
kaouane chouaib0
@KChouaib017109 · X

RT @NEJM: In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therap…

Oct 13, 2025 · 5 shares · 4 followers View post →
dr.jov
@drjov10 · X

RT @NEJM: In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therap…

Oct 13, 2025 · 5 shares · 109 followers View post →
Miguel Marcos
@drmiguelmarcos · X

Baxdrostat (inhibidor de aldosterona) logra objetivo primario en fase 3 y baja la presión en hipertensión resistente. Artículo en @NEJM https://t.co/fIsSCJQMAs

Oct 13, 2025 · 1 like · 57,833 followers View post →
Edgar Fránquez
@EdgarFrnquez1 · X

RT @NEJM: In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therap…

Oct 13, 2025 · 5 shares · 12 followers View post →
Omar Habib
@cancerologyo · X

RT @NEJM: In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therap…

Oct 13, 2025 · 5 shares · 7 followers View post →
Dr. Fernando
@rotavirus1980 · X

Eficacia y seguridad de baxdrostat en la hipertensión no controlada y resistente | Revista de Medicina de Nueva Inglaterra https://t.co/5GuN7ZAsHx

Oct 13, 2025 · 187 followers View post →
Mark Anderson
@delanceydaily · X

RT @NEJM: In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therap…

Oct 13, 2025 · 5 shares · 1,863 followers View post →
NEJM.org
@nejm.org · Bluesky

In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therapy led to a lower seated systolic blood pressure than placebo at 12 weeks. Full trial results and Research Summary: nej.md/4my7xUZ #MedSky #CardioSky

Oct 13, 2025 · 6 likes · 2 shares View post →
NEJM
@NEJM · X

In the BaxHTN phase 3 trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therapy led to a lower seated systolic blood pressure than placebo at 12 weeks. Full trial results and Research Summary: https://t.co/iRVxdmp7Ss https://t.co/UWfk8wIufr

Oct 13, 2025 · 46 likes · 5 shares · 936,101 followers View post →
MEDICAL TRAINING SUPPORT- MEDSUP S.A
@mts_ecuador · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 200 followers View post →
Ignacio Monteón
@imonteon · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 479 followers View post →
Carmela Ramos
@Carmen98607067 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 6 followers View post →
Georgios Kyriakos
@giorg_kyriakos · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 1,206 followers View post →
paulo wolf
@baddragon007 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 93 followers View post →
dr
@drswsayed · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 91 followers View post →
Franklin Loachamin
@FranLoachamin · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 4,887 followers View post →
AliciaLee MD
@Alicia0319Lee · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 208 followers View post →
777
@crabgirl87 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 67 followers View post →
Tu Nutrióloga MX
@MxNutriologa · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 49 followers View post →
Marinos Gkounes
@MarinosGkounes · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 166 followers View post →
Dr.Lawrence Lawino _K
@LawrenceAwino · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 232 followers View post →
Felice Gragnano
@FeliceGragnano · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 5,362 followers View post →
Ivonne Torres-Atencio
@negrita73bn · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 2,381 followers View post →
DrMugeloveskidneys
@smuge2 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 399 followers View post →
Máximo Bernabeu
@MximoWittel · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 1,100 followers View post →
i̷_̷a̷m̷_̷m̷a̷r̷t̷y̷n̷
@kugonza6 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 1,069 followers View post →
Teresa Gijon Conde
@TGijonConde · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 1,054 followers View post →
Oscar Aspiazu Segovia. MD. ESP. MFYC| MsC.MPH
@opolito8514 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 284 followers View post →
drhungicu
@drhungicu · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 87 followers View post →
Michele Emdin
@MicheleEmdin · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 1,015 followers View post →
Dr. Christian Velasquez
@drchvelasquezb · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 110 followers View post →
Wimen
@1a31551c566e43d · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 671 followers View post →
X_MEDICINE_X
@XMedicinedoc · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 12, 2025 · 92 shares · 80 followers View post →
Curie-osity
@Annisaragi · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 257 followers View post →
Elad Sharon
@EladSharonMD · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 3,866 followers View post →
Almansour
@malmansour81 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 214 followers View post →
anymzcs
@anymzcs · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 44,144 followers View post →
Yanamandra Sastri
@Yanamandra70982 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 94 followers View post →
Mario Alamilla-Sánchez
@MarioAlamilla · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 1,014 followers View post →
A K
@annafval · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 204 followers View post →
Ari Johar
@Arijohar · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 524 followers View post →
C.K.
@firesigh · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 16 followers View post →
Dr. Carlos Orellana
@orellanamd · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 551 followers View post →
Letaief
@hmidato · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 370 followers View post →
Manuel Méndez
@mendez_bailon · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 7,784 followers View post →
Dr Benil
@hafeeq_benil · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 391 followers View post →
Herbs and Havoc
@HerbsAndHavoc · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 324 followers View post →
Nora
@Noralzahrani · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 365 followers View post →
Ramon Rivera ☕️
@RamonRiv92 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 342 followers View post →
TheKnightofEvening
@KnightofTh3v3ng · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 2,412 followers View post →
Martin Correa
@martinrafco · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 231 followers View post →
TAATJENE Food Industries
@taatjene1123 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 308 followers View post →
andres
@palacioendocrin · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 371 followers View post →
Mo H.
@Mahmoud59362551 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 135 followers View post →
DrJMLuther
@DrJMLuther · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 2,628 followers View post →
Jinn-Yuh Guh
@guhjy · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 136 followers View post →
Pokrath Hansasuta
@pokrath · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 94,500 followers View post →
Manuel Gaxiola
@cardiogax · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 7,990 followers View post →
Carlos Ávila
@CarlosAR016 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 278 followers View post →
Dr. Gilberto Pérez López MD PhD
@Endocrino_PED · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 4,799 followers View post →
Daniel Pita, MD
@danpita · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 1,302 followers View post →
Gibran Bello
@gibranbello · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 141 followers View post →
Gabi
@GabrielBuadesLu · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 159 followers View post →
fghp
@david464 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 163 followers View post →
rattana thiray
@RThiray77123 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 35 followers View post →
Blessing Muponda
@BMuponda · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 100 followers View post →
Manuel Alvarez
@manucardio84 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 42 followers View post →
Victoria Luna
@VictoriaLuna4 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 1,579 followers View post →
Obada Salameh , MD
@obada_dr · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 142 followers View post →
Jean-François RENUCCI
@JF_Renucci · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 174 followers View post →
Rx Readmore Livemore
@SopitaSirirata1 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 171 followers View post →
Shammari
@Shimri17 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 752 followers View post →
Mana
@manasigh · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 332 followers View post →
SergitoMelnick
@caminoportodos · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 144 followers View post →
HerniaHerney
@HerniaHerney · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 27 followers View post →
ملتقى علوم الاحياء
@Biology1802 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 54,577 followers View post →
Nada Hassib
@NadaHassib1 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 767 followers View post →
Mohammad Aleidi
@aleidimed · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 314 followers View post →
Ans Alamami
@ANS_ALAMAMI · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 190 followers View post →
Cristina Tejera
@cristinatejerap · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 11,477 followers View post →
Flavio Gargano
@GarganoFlavio · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 11, 2025 · 92 shares · 161 followers View post →
KIN LOPEZ
@KINWAHSIU · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 190 followers View post →
Somaditya Bandyopadhyay
@somsuj · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 395 followers View post →
mohamed
@stckmktaddict · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 1,226 followers View post →
orion77
@orion7710 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 1,492 followers View post →
GVATAKEN
@VISLAMDSCAIP · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 1,208 followers View post →
Francisca Martínez
@famartinez2001 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 10,036 followers View post →
Ranvier90, MD, Ph.D.
@ranvier90 · X

RT @NEJM: Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.c…

Oct 10, 2025 · 92 shares · 80 followers View post →
NEJM
@NEJM · X

Original Article: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) https://t.co/iRVxdmp7Ss Editorial: Aldosterone Synthase Inhibition for Hypertension https://t.co/qAx3z4Iy7s #Cardiology https://t.co/lmQPkR8Na7

Oct 10, 2025 · 321 likes · 92 shares · 936,101 followers View post →
Wimen
@1a31551c566e43d · X

RT @NEJM: New in the October 9, 2025, issue of NEJM: Baxdrostat Efficacy and Safety in Uncontrolled Hypertension (BaxHTN phase 3 trial)…

Oct 10, 2025 · 6 shares · 671 followers View post →
Andrew Gabrielson
@urogabe · X

RT @NEJM: New in the October 9, 2025, issue of NEJM: Baxdrostat Efficacy and Safety in Uncontrolled Hypertension (BaxHTN phase 3 trial)…

Oct 9, 2025 · 6 shares · 1,250 followers View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

“Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension.” Publié ce jour dans le @nejm.org. #MedSky www.nejm.org/doi/full/10....

Oct 9, 2025 View post →
いまちにぶりっくす
@haematolo · X

アルドステロン合成酵素阻害剤なんてのがあるのね、CYP11B2を選択的に阻害するとか ステムは-drostatか Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | New England Journal of Medicine https://t.co/2KYcRqFq9E

Oct 8, 2025 · 1 like · 33 followers View post →
Muzamil L. Banday
@muzamilkidney · X

Another molecule in the armamentarium ! Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | New England Journal of Medicine https://t.co/vr0D6XI9Se

Oct 6, 2025 · 551 followers View post →
Abdallah Al-Mohammad
@AAlMohammad87 · X

Interesting new result from @escardio #ESC2025 @NEJM the #BaxHTN study showed the aldosterone synthase inhibitor #Baxtrostat significantly lowered the seated sBP at 12 weeks in pts with uncontrolled hypertension #cardiotwitter @SheffieldHosp https://t.co/RSrLmST33f

Sep 24, 2025 · 2 likes · 927 followers View post →
Aycan Erkan
@AycanErkan10 · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 18, 2025 · 10 shares · 357 followers View post →
Ananya Vihaan
@ananya_vihaan · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 84 followers View post →
Ripusudan Srivastava
@RipusudanSriva2 · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 1,846 followers View post →
Luck InHeels
@LuckInHeels147 · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 354 followers View post →
Dr.AMiT JAiSWAL
@aadvikmedics · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 64 followers View post →
Poonam Velagapudi
@Pooh_Velagapudi · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 11,732 followers View post →
Almansour
@malmansour81 · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 214 followers View post →
Dr Anastasia Mihailidou FAHA FCSANZ FESC
@AnastasiaSMihai · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 19,312 followers View post →
LS
@LiliaSierra2 · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 2,517 followers View post →
Hany Ragy
@Hragy · X

RT @drbennisahmed: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resist…

Sep 17, 2025 · 10 shares · 80,489 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension Among patients with uncontrolled or resistant hypertension, the addition of baxdrostat to background therapy resulted in a significantly lower seated systolic blood pressure at 12 weeks than placebo. https://t.co/GfmsNRPEYt

Sep 17, 2025 · 41 likes · 10 shares · 2,774 followers View post →
University of Utah Health Research
@uuhsresearch.bsky.social · Bluesky

Jamie Dwyer, MD, led one of two large clinical trials for baxdrostat, which have been widely recognized as a breakthrough in hypertension care. Nearly half of U.S. adults are affected.https://www.nejm.org/doi/full/10.1056/NEJMoa2507109

Sep 15, 2025 · 1 like View post →
Ibrahim Khan
@iakhan13.bsky.social · Bluesky

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | New England Journal of Medicine www.nejm.org/doi/full/10....

Sep 10, 2025 View post →
Andy_Weeble_Weaver
@AndrewW66619812 · X

The paper in "NEJM" on one of the new drugs the above article in "Nature Reviews Drug Discovery" is based upon & links to: “Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension” 2/ https://t.co/9qn15ae3OE

Sep 10, 2025 · 4,327 followers View post →
STITCHES Medicine - the Best of Medical Research
@STITCHESMed · X

Baxdrostat significantly lowers blood pressure in patients with uncontrolled or resistant hypertension compared to placebo, showing potent efficacy. by Flack JM, Azizi M (...) Williams B et 10 al. in N Engl J Med https://t.co/akwuBB5j2Z #MedX #MedResearch

Sep 8, 2025 · 88 followers View post →
@MARTINSVEL
@MARTINSVEL · X

RT @nicolasrennamd: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | New England Journal of Medicine https://…

Sep 8, 2025 · 2 shares · 412 followers View post →
Jean-François RENUCCI
@JF_Renucci · X

RT @nicolasrennamd: Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | New England Journal of Medicine https://…

Sep 8, 2025 · 2 shares · 174 followers View post →
Nicolas Renna, MD PhD ISHF FESC
@nicolasrennamd · X

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | New England Journal of Medicine https://t.co/2lKpYGeQEt

Sep 7, 2025 · 4 likes · 2 shares · 935 followers View post →
pinacol
@pinacol · X

【RCT】利尿剤を含む2剤以上の降圧剤または3剤以上の降圧剤を服用しているにもかかわらず収縮期血圧が140から170mmHg未満の間の患者へのBaxdrostat投与は、プラセボの投与と比較して、収縮期血圧を減少させた。 #ペ読 https://t.co/x66mWOO0LH

Sep 7, 2025 · 1 like · 1,617 followers View post →
markusathome
@markusathome.bsky.social · Bluesky

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension by Drs. Flack, Williams, et al. www.nejm.org/doi/full/10.... The addition of baxdrostat to background therapy resulted in a significantly lower seated systolic blood pressure at 12 weeks than placebo.

Sep 4, 2025 · 1 like View post →
Thanh Nha Thai, MD
@thaithanhnha.bsky.social · Bluesky

A new treament - Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension. www.nejm.org/doi/full/10.... @escardio.bsky.social @nejm.org #CardioSky #ESC2025 #ESCCongress

Aug 30, 2025 · 1 like · 1 share View post →
Errant Thoughts
@ErrantThoughts · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 281 followers View post →
Fandomguy (Destructive Creation arc)
@sciencefandom · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 927 followers View post →
Misha Booltink
@MishaBooltink · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 542 followers View post →
strawberry
@strawberry88122 · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 1,122 followers View post →
Luis Alberto Luengo
@luengo1958 · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 17,889 followers View post →
juan m garcia cuevas
@Geol_juanm · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 218 followers View post →
Seraphina
@Ricky0227Ricky · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 38 followers View post →
PsyberspaceSuperstar
@psybrspcsuprstr · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 1,577 followers View post →
DGG
@DGG7334 · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 113 followers View post →
Phys.org
@physorg_com · X

RT @medical_xpress: An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-re…

Aug 30, 2025 · 21 shares · 1,024,235 followers View post →
Medical Xpress
@medical_xpress · X

An experimental drug targeting #Aldosterone imbalance significantly lowers blood pressure in patients with treatment-resistant #Hypertension, offering a promising new option for improved cardiovascular outcomes. @uclnews @nejm https://t.co/lbdwIi3zHg https://t.co/ZIfKg275zh

Aug 30, 2025 · 24 likes · 21 shares · 173,154 followers View post →
NEJM.org
@nejm.org · Bluesky

Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension (BaxHTN phase 3 trial) nej.md/4my7xUZ Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia (ESSENCE–TIMI 73b Phase 3 trial) nej.md/4mws7Vt

Aug 30, 2025 · 1 share View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

“Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension.” Présenté ce jour à #ESCCongress et publié dans le @nejm.org. #MedSky #CardioSky #ESC2025 www.nejm.org/doi/full/10....

Aug 30, 2025 View post →