38,848 results match your criteria: "Chimera"

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Diverse genetic mechanisms underlie worldwide convergent rice feralization.
Jie Qiu, Lei Jia, Dongya Wu, Xifang Weng, Lijuan Chen

March 2020

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Sex redefined.
Claire Ainsworth

Nature· February 2015

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Chimeric antigen receptor T cells for sustained remissions in leukemia.
Shannon L Maude, Noelle Frey, Pamela A Shaw, Richard Aplenc, David M Barrett

N Engl J Med· October 2014

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Disputed maternity leading to identification of tetragametic chimerism.
Neng Yu, Margot S Kruskall, Juan J Yunis, Joan H M Knoll, Lynne Uhl

May 2002

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Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation.
Daniel Schäfer, Cristian Prieto-Garcia, Jianhui Wang, Marcel Heinz, Vigor Matkovic

Angew Chem Int Ed Engl· December 2025

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Targeting KRAS G12D: Advances in Inhibitor Design.
Kaiyin Shi, Amin Li

Thorac Cancer· December 2025

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Molecular mechanisms for the activation of human organic anion transporting polypeptide 1B3 by quercetin-3-O-α-L-arabinopyranosyl(1 → 2)-α-L-rhamnopyranoside.
Ru Huan, Peigen Xu, Shuang Chen, Yao Dong, Chen Zhang

Int J Biol Macromol· December 2025

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Recent advances in antitumor indole-chalcone derivatives: a mini review.
Guangyuan Liu, Yawei Han, Yuhao Wei, Pengyu Qian, Yirong Zhou

Eur J Pharmacol· December 2025

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Simulated use of the Water Circuit Disinfection Device on a Mycobacterium chimaera-contaminated LivaNova 3T Heater Cooler Device - results of mycobacterial and bacterial surveillance: Abbreviated title: WCDD on M. chimaera-contaminated HCD.
C Reiber, T Aigner, B Chakrakodi, M Dunic, S Ernst

J Hosp Infect· December 2025

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Conformation-Dependent Complexation Interactions for a SMARCA2 PROTAC and Cyclodextrin.
Matthew N O'Brien Laramy, José G Napolitano, Yuhui Zhou, David J Russell, Sarah Robinson

Mol Pharm· December 2025

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Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities.
Jianfeng Ge, Shoko Hirosue, Leticia Castillon, Saroor A Patel, Ludovic Wesolowski

EMBO Mol Med· December 2025

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Synthesis and identification of a novel selective USP7 degrader that inhibits the migration of upper gastrointestinal cancer cells without affecting proliferation.
Xu-Bin Ma, Kai Sun, Yuan-Yuan Liu, Liang Wang, Chen-Ran Lu

Eur J Med Chem· December 2025

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Novel PROTACs with polyhedral alkanes as linkers for enhanced ALK degradation in drug-resistant NSCLC.
Dongchen Chu, Huijie Han, Chaochun Wei, Xiaokun Zhang, Hong Yan

Bioorg Med Chem· December 2025

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Dietary patterns and breast cancer risk: a large-scale case control study among Moroccan women.
Najoua Lamchabbek, Najia Mane, Siham Mrah, Chaimaa Elattabi, Zineb Ourrad

Eur J Nutr· December 2025

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Proteolysis Targeting Chimera Loaded Extracellular Vesicles for Developing Triple Negative Breast Cancer Treatment.
Nina Erwin, Umasankar De, Yufeng Xiao, Lei Wang, Chandra K Maharjan

J Extracell Vesicles· December 2025

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Computational Modeling of PROTAC Ternary Complexes as Ensembles Using SILCS-xTAC.
Erik B Nordquist, Mingtian Zhao, Wenbo Yu, Alexander D MacKerell

J Chem Inf Model· December 2025

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Autophagosome degraders: a novel therapeutic strategy with broad application potential in human diseases.
Wei-Fang Zuo, Xinyi Huang, Cheng Peng, Bo Han, Qian Zhao

Future Med Chem· December 2025

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Conserved inter-domain interactions drive trans-Golgi network localisation and trafficking of homologous copper-ATPases.
Sharon Mary Jose, Saptarshi Maji, Mrittika Paul, Chirag Singhal, Sreeramaiah N Gangappa

J Cell Sci· December 2025

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Phenotypic Variability and Paternal Inheritance of a CHD8 Variant Causing Intellectual Developmental Disorder With Autism and Macrocephaly Confirmed by Epigenetic and Structural Analyses.
Yutaka Furuta, Kimberly M Ezell, Rizwan Hamid, Joy D Cogan, Thomas A Cassini

Mol Genet Genomic Med· December 2025

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Investigating the olfactory function of microplusin-like proteins in Rhipicephalus microplus through molecular docking and dynamics simulations.
Afito Luciano, Yuxin Huo, Sha Tan, Mandie Liu, Yuting Ma

Vet Parasitol· December 2025

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Identification of N-tert-butyloxycarbonyl protected amino acids as novel hydrophobic tags to induce targeted protein degradation.
Hui Sun, Xueyi Luo, Hengjie Hu, Cong Li, Cheng Lyu

Eur J Med Chem· December 2025

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"The RAS Dam Has Broken".

Cancer Discov· December 2025

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Recent Developments in Cyclin-Dependent Kinase (CDK) PROTAC in Cancer Therapy.
Arijit Nandi, Anwesha Das, M Rhia L Stone, Mark A T Blaskovich

ACS Med Chem Lett· December 2025

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Isodrimenine Derivatives Selectively Inhibit Human α7-Containing Nicotinic Acetylcholine Receptors via Negative Allosteric Modulation.
Han-Shen Tae, Marcelo O Ortells, Alexandru Ciocarlan, Aculina Aricu, Lidia Lungu

ACS Chem Neurosci· December 2025

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Development of Cathepsin B-Responsive GalNAc-PROTACs for Hepatocyte-Targeting Protein Degradation.
Yunhua Peng, Tao Li, Donghua Liu, Wenxin Li, Yimeng Zhang

J Med Chem· December 2025

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Targeting tumor-infiltrating regulatory T cells: combining CD47 and PD-L1 inhibition via a novel aptamer-siRNA chimera.
Yu Zeng, Xiaoli Chen, Wenqiong Huang, Chi Ho Chan, Ziqi Chen

Mol Biomed· December 2025

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Antibody-lectin chimeras for glyco-immune checkpoint blockade.
Jessica C Stark, Melissa A Gray, Itziar Ibarlucea-Benitez, Marta Lustig, Annalise Bond

Nat Biotechnol· December 2025

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A Facile Protocol for C(sp)-C(sp) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands.
Anita Maksutova, Thomas M Geiger, Lorenzo Cianni, Dominika E Pieńkowska, Jan Gerhartz

ChemMedChem· December 2025

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Exposing Hidden Binding Pockets in Cereblon: His378 Conformational Dynamics Inform Novel Ligand Design.
Jiangnan Du, Cunhong Luo, Jin Feng, Xianqiang Sun, Yaozong Li

J Phys Chem B· December 2025

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Targeted degradation of estrogen receptor β to overcome Osimertinib resistance in non-small cell lung carcinoma.
Yunchong Meng, Xiaofei Deng, Baohua Xie, Wei Lin, Na Wang

Bioorg Chem· December 2025

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Development of glucagon-like Peptide-1 lysosomal targeting chimeras for degradation of extracellular and membrane proteins.
Liquan Zhu, Haotian Liu, Xin Zeng, Ke Liu, Xiaozhen Liu

Eur J Med Chem· December 2025

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