Publications by authors named "Adam Darwich"

Claim this Profile
C
Concentration-dependent blood binding: assessing implications through physiologically based Pharmacokinetic modeling of tacrolimus as a case example.
Eman El-Khateeb, Deeyen Karsanji, Adam S Darwich, Amin Rostami-Hodjegan

J Pharmacokinet Pharmacodyn· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Issues in Identifying Strategies for Youth Mental Well-Being in Stockholm Municipalities Using Participatory Sessions and Text Mining: Qualitative Study.
Harsha Krishna, Adam S Darwich, Sebastiaan Meijer

Online J Public Health Inform· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A dynamic nonlinear flow algorithm to model patient flow.
Arsineh Boodaghian Asl, Jayanth Raghothama, Adam S Darwich, Sebastiaan Meijer

Sci Rep· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploring the discrepancies between clinical trials and real-world data: A small-cell lung cancer study.
Luca Marzano, Adam S Darwich, Asaf Dan, Salomon Tendler, Rolf Lewensohn

Clin Transl Sci· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploring Hospital Overcrowding with an Explainable Time-to-Event Machine Learning Approach.
Tobias Haraldsson, Luca Marzano, Harsha Krishna, Sven Lethval, Nina Falk, Adam S Darwich

Stud Health Technol Inform· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Population Pharmacokinetic Analysis and Simulation of Alternative Dosing Regimens for Biosimilars to Adalimumab and Etanercept in Patients with Rheumatoid Arthritis.
Stephanie F Ling, Kayode Ogungbenro, Adam S Darwich, Amirah Binti Mohammad Ariff, Nisha Nair

Pharmaceutics· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diagnosing an overcrowded emergency department from its Electronic Health Records.
Luca Marzano, Adam S Darwich, Raghothama Jayanth, Lethvall Sven, Nina Falk

Sci Rep· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Using Prior Knowledge on Systems Through PBPK to Gain Further Insight into Routine Clinical Data on Trough Concentrations: The Case of Tacrolimus in Chronic Kidney Disease.
Eman El-Khateeb, Rajkumar Chinnadurai, Jokha Al Qassabi, Daniel Scotcher, Adam S Darwich

Ther Drug Monit· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigating the Connections Between Delivery of Care, Reablement, Workload, and Organizational Factors in Home Care Services: Mixed Methods Study.
Adam S Darwich, Anne-Marie Boström, Susanne Guidetti, Jayanth Raghothama, Sebastiaan Meijer

JMIR Hum Factors· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Application of Process Mining for Modelling Small Cell Lung Cancer Prognosis.
Luca Marzano, Sebastiaan Meijer, Asaf Dan, Salomon Tendler, Luigi De Petris, Adam S Darwich

Stud Health Technol Inform· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel analytical framework for risk stratification of real-world data using machine learning: A small cell lung cancer study.
Luca Marzano, Adam S Darwich, Salomon Tendler, Asaf Dan, Rolf Lewensohn

Clin Transl Sci· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective.
Clive G Wilson, Leon Aarons, Patrick Augustijns, Joachim Brouwers, Adam S Darwich

Eur J Pharm Sci· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series.
Mark McAllister, Talia Flanagan, Susan Cole, Andreas Abend, Evangelos Kotzagiorgis, Adam Darwich

Pharmaceutics· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A latent variable approach to account for correlated inputs in global sensitivity analysis.
Nicola Melillo, Adam S Darwich

J Pharmacokinet Pharmacodyn· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Review article: time to revisit Child-Pugh score as the basis for predicting drug clearance in hepatic impairment.
Eman El-Khateeb, Adam S Darwich, Brahim Achour, Varinder Athwal, Amin Rostami-Hodjegan

Aliment Pharmacol Ther· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in Rats.
Daniel Scotcher, Nicola Melillo, Sirisha Tadimalla, Adam S Darwich, Sabina Ziemian

Mol Pharm· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy.
Adam S Darwich, Thomas M Polasek, Jeffrey K Aronson, Kayode Ogungbenro, Daniel F B Wright

Annu Rev Pharmacol Toxicol· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Amais Ahmad, Xavier Pepin, Leon Aarons, Yuya Wang, Adam S Darwich

Eur J Pharm Biopharm· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Application of the Nested Enzyme-Within-Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects.
Hiroyuki Takita, Adam S Darwich, Amais Ahmad, Amin Rostami-Hodjegan

CPT Pharmacometrics Syst Pharmacol· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue Distribution.
Estelle Yau, Andrés Olivares-Morales, Michael Gertz, Neil Parrott, Adam S Darwich

AAPS J· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.
Michael X Henderson, Eli J Cornblath, Adam Darwich, Bin Zhang, Hannah Brown

Nat Neurosci· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Impact of Formulation, Delivery, and Dosing Regimen on the Risk of Drug-Drug Interactions.
Adam S Darwich, Lisa von Moltke

Clin Pharmacol Ther· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The nested enzyme-within-enterocyte (NEWE) turnover model for predicting dynamic drug and disease effects on the gut wall.
Adam S Darwich, Howard J Burt, Amin Rostami-Hodjegan

Eur J Pharm Sci· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Accounting for inter-correlation between enzyme abundance: a simulation study to assess implications on global sensitivity analysis within physiologically-based pharmacokinetics.
Nicola Melillo, Adam S Darwich, Paolo Magni, Amin Rostami-Hodjegan

J Pharmacokinet Pharmacodyn· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing.
Thomas M Polasek, Amin Rostami-Hodjegan, Dong-Seok Yim, Masoud Jamei, Howard Lee, Adam S Darwich

AAPS J· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis