Publications by authors named "Adam Shutes"

Claim this Profile
D
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
Richard D Caldwell, Hui Qiu, Ben C Askew, Andrew T Bender, Nadia Brugger, Adam Shutes

J Med Chem· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A precision therapy against cancers driven by mutations.
Erica K Evans, Alexandra K Gardino, Joseph L Kim, Brian L Hodous, Adam Shutes

Sci Transl Med· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.
Margit Hagel, Chandra Miduturu, Michael Sheets, Nooreen Rubin, Weifan Weng, Adam Shutes

Cancer Discov· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Srinivasa Karra, Yufang Xiao, Xiaoling Chen, Lesley Liu-Bujalski, Bayard Huck, Adam Shutes

Bioorg Med Chem Lett· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Allosteric IGF-1R Inhibitors.
Timo Heinrich, Ulrich Grädler, Henning Böttcher, Andree Blaukat, Adam Shutes

ACS Med Chem Lett· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Capillary microfluidic electrophoretic mobility shift assays: application to enzymatic assays in drug discovery.
Dominique Perrin, Christèle Frémaux, Adam Shutes

Expert Opin Drug Discov· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis.
Adam Shutes, Channing J Der

Methods Enzymol· June 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
Cercina Onesto, Adam Shutes, Virginie Picard, Fabien Schweighoffer, Channing J Der

Methods Enzymol· June 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms.
Kevin D Healy, Louis Hodgson, Tai-Young Kim, Adam Shutes, Savitri Maddileti

Mol Carcinog· May 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
Adam Shutes, Cercina Onesto, Virginie Picard, Bertrand Leblond, Fabien Schweighoffer

J Biol Chem· December 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biochemical analyses of the Wrch atypical Rho family GTPases.
Adam Shutes, Anastacia C Berzat, Emily J Chenette, Adrienne D Cox, Channing J Der

Methods Enzymol· March 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Real-time in vitro measurement of GTP hydrolysis.
Adam Shutes, Channing J Der

Methods· October 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transforming activity of the Rho family GTPase, Wrch-1, a Wnt-regulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif.
Anastacia C Berzat, Janice E Buss, Emily J Chenette, Carolyn A Weinbaum, Adam Shutes

J Biol Chem· September 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase.
Adam Shutes, Anastacia C Berzat, Adrienne D Cox, Channing J Der

Curr Biol· November 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.
Randall J Kimple, Miller B Jones, Adam Shutes, Benjamin R Yerxa, David P Siderovski

Comb Chem High Throughput Screen· June 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of magnesium in nucleotide exchange on the small G protein rac investigated using novel fluorescent Guanine nucleotide analogues.
Adam Shutes, Robert A Phillips, John E T Corrie, Martin R Webb

Biochemistry· March 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis