Publications by authors named "Agnes Rinaldo-Matthis"

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Discovery of a small molecule that inhibits Bcl-3-mediated cyclin D1 expression in melanoma cells.
Karunakar Saamarthy, Kristofer Ahlqvist, Renée Daams, Navisraj Balagunaseelan, Agnes Rinaldo-Matthis

BMC Cancer· January 2024

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Crystal structures of human MGST2 reveal synchronized conformational changes regulating catalysis.
Madhuranayaki Thulasingam, Laura Orellana, Emmanuel Nji, Shabbir Ahmad, Agnes Rinaldo-Matthis

Nat Commun· March 2021

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Investigation of calcium-dependent activity and conformational dynamics of zebra fish 12-lipoxygenase.
Monica Mittal, Mahmudul Hasan, Navisraj Balagunaseelan, Alexander Fauland, Craig Wheelock, Agnes Rinaldo-Matthis

Biochim Biophys Acta Gen Subj· August 2017

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Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase.
Marcus Cebula, Ilke Simsek Turan, Birgitta Sjödin, Madhuranayaki Thulasingam, Joseph Brock, Agnes Rinaldo-Matthis

Sci Rep· December 2016

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Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to Nanodiscs.
Ramakrishnan B Kumar, Lin Zhu, Helena Idborg, Olof Rådmark, Per-Johan Jakobsson, Agnes Rinaldo-Matthis

PLoS One· August 2016

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Kinetic investigation of human 5-lipoxygenase with arachidonic acid.
Monica Mittal, Ramakrishnan B Kumar, Navisraj Balagunaseelan, Mats Hamberg, Caroline Jegerschöld, Agnes Rinaldo-Matthis

Bioorg Med Chem Lett· August 2016

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Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.
Shabbir Ahmad, A Jimmy Ytterberg, Madhuranayaki Thulasingam, Fredrik Tholander, Tomas Bergman, Agnes Rinaldo-Matthis

J Biol Chem· August 2016

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A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase.
Joseph S Brock, Mats Hamberg, Navisraj Balagunaseelan, Michael Goodman, Ralf Morgenstern, Agnes Rinaldo-Matthis

Proc Natl Acad Sci U S A· January 2016

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Trimeric microsomal glutathione transferase 2 displays one third of the sites reactivity.
Shabbir Ahmad, Madhuranayaki Thulasingam, Isolde Palombo, Daniel O Daley, Kenneth A Johnson, Agnes Rinaldo-Matthis

Biochim Biophys Acta· October 2015

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Structure and inhibition of mouse leukotriene C4 synthase.
Damian Niegowski, Thea Kleinschmidt, Shabbir Ahmad, Abdul Aziz Qureshi, Michaela Mårback, Agnes Rinaldo-Matthis

PLoS One· January 2015

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A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity.
Marija Rakonjac Ryge, Michiharu Tanabe, Patrick Provost, Bengt Persson, Xinsheng Chen, Agnes Rinaldo-Matthis

Arch Biochem Biophys· March 2014

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Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor.
Alena Stsiapanava, Ulrika Olsson, Min Wan, Thea Kleinschmidt, Dorothea Rutishauser, Agnes Rinaldo-Matthis

Proc Natl Acad Sci U S A· March 2014

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Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.
Alena Stsiapanava, Fredrik Tholander, Ramakrishnan B Kumar, Abdul Aziz Qureshi, Damian Niegowski, Agnes Rinaldo-Matthis

Biochim Biophys Acta· February 2014

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Crystal structures of leukotriene C4 synthase in complex with product analogs: implications for the enzyme mechanism.
Damian Niegowski, Thea Kleinschmidt, Ulrika Olsson, Shabbir Ahmad, Agnes Rinaldo-Matthis

J Biol Chem· February 2014

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Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps.
Shabbir Ahmad, Damian Niegowski, Anders Wetterholm, Jesper Z Haeggström, Ralf Morgenstern, Agnes Rinaldo-Matthis

Biochemistry· March 2013

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A picomolar transition state analogue inhibitor of MTAN as a specific antibiotic for Helicobacter pylori.
Shanzhi Wang, Antti M Haapalainen, Funing Yan, Quan Du, Peter C Tyler, Agnes Rinaldo-Matthis

Biochemistry· September 2012

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Pre-steady-state kinetic characterization of thiolate anion formation in human leukotriene C₄ synthase.
Agnes Rinaldo-Matthis, Shabbir Ahmad, Anders Wetterholm, Peter Lachmann, Ralf Morgenstern

Biochemistry· January 2012

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A high-affinity adenosine kinase from Anopheles gambiae.
María B Cassera, Meng-Chiao Ho, Emilio F Merino, Emmanuel S Burgos, Agnes Rinaldo-Matthis

Biochemistry· March 2011

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Arginine 104 is a key catalytic residue in leukotriene C4 synthase.
Agnes Rinaldo-Matthis, Anders Wetterholm, Daniel Martinez Molina, Johanna Holm, Damian Niegowski

J Biol Chem· December 2010

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Structures and mechanisms of enzymes in the leukotriene cascade.
Agnes Rinaldo-Matthis, Jesper Z Haeggström

Biochimie· June 2010

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Advances in eicosanoid research, novel therapeutic implications.
Jesper Z Haeggström, Agnes Rinaldo-Matthis, Craig E Wheelock, Anders Wetterholm

Biochem Biophys Res Commun· May 2010

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Four generations of transition-state analogues for human purine nucleoside phosphorylase.
Meng-Chiao Ho, Wuxian Shi, Agnes Rinaldo-Matthis, Peter C Tyler, Gary B Evans

Proc Natl Acad Sci U S A· March 2010

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Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
Jemy A Gutierrez, Tamara Crowder, Agnes Rinaldo-Matthis, Meng-Chiao Ho, Steven C Almo

Nat Chem Biol· April 2009

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L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
Agnes Rinaldo-Matthis, Andrew S Murkin, Udupi A Ramagopal, Keith Clinch, Simon P H Mee

J Am Chem Soc· January 2008

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Crystal structures of human and murine deoxyribonucleotidases: insights into recognition of substrates and nucleotide analogues.
Karin Walldén, Agnes Rinaldo-Matthis, Benedetta Ruzzenente, Chiara Rampazzo, Vera Bianchi

Biochemistry· December 2007

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