Publications by authors named "Al Charest"

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Heterogeneity of Extracellular Vesicles and Non-Vesicular Nanoparticles in Glioblastoma.
Tuoye Xu, Joao A Paulo, Piyan Zhang, Xinyue Liu, Alya Nguyen, Al Charest

J Extracell Vesicles· October 2025

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Surface Markers on Supermeres Outperform Extracellular Vesicles in Cancer Diagnosis.
Sonu Kumar, John Alex Sinclair, Tiger Shi, Gaeun Kim, Runyao Zhu, Al Charest

medRxiv· October 2025

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Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions.
Saad M Khan, Anthony Z Wang, Rupen R Desai, Colin R McCornack, Rui Sun, Al Charest

bioRxiv· April 2025

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Peptides from abnormal RNA processing in cancer offer an immunotherapy target.
Al Charest

Nature· March 2025

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Pleiotropic tumor suppressive functions of PTEN missense mutations during gliomagenesis.
Hyun Jung Jun, Joao A Paulo, Victoria A Appleman, Tomer M Yaron-Barir, Jared L Johnson, Al Charest

iScience· December 2024

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Comparison of EV characterization by commercial high-sensitivity flow cytometers and a custom single-molecule flow cytometer.
James Kim, Shihan Xu, Seung-Ryoung Jung, Alya Nguyen, Yuanhua Cheng, Al Charest

J Extracell Vesicles· August 2024

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The EV antibody database: An interactive database of curated antibodies for extracellular vesicle and nanoparticle research.
Amber Morey, Martin Ng, Michail Spanos, Piyan Zhang, Tuoye Xu, Al Charest

Extracell Vesicle· June 2024

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Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma.
Alan T Yeo, Rushil Shah, Konstantinos Aliazis, Rinku Pal, Tuoye Xu, Al Charest

Cancer Immunol Res· May 2023

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Male sterility in ROS1 receptor tyrosine kinase conditionally deleted in epididymal epithelial.
Hyun Jung Jun, Ziad A Ali, Al Charest

Biochim Biophys Acta Mol Cell Res· March 2023

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Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.
Bogdan Mateescu, Jennifer C Jones, Roger P Alexander, Eric Alsop, Ji Yeong An, Al Charest

iScience· August 2022

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Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression.
Alan T Yeo, Shruti Rawal, Bethany Delcuze, Anthos Christofides, Agata Atayde, Al Charest

Nat Immunol· June 2022

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EGFRvIII tumorigenicity requires PDGFRA co-signaling and reveals therapeutic vulnerabilities in glioblastoma.
Alan T Yeo, Hyun Jung Jun, Vicky A Appleman, Piyan Zhang, Hemant Varma, Al Charest

Oncogene· April 2021

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A high-grade glioma with amplification.
Barbara Vidal, Christine Bryke, Nancy Hsu, Ronnie Alterman, Alan T Yeo, Al Charest

Clin Neuropathol· March 2021

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Experimental and Biological Insights from Proteomic Analyses of Extracellular Vesicle Cargos in Normalcy and Disease.
Al Charest

Adv Biosyst· December 2020

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Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Aron Gyuris, Jose Navarrete-Perea, Ala Jo, Simona Cristea, Shuang Zhou, Al Charest

Cell Rep· June 2019

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A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Hyun Jung Jun, Vicky A Appleman, Hua-Jun Wu, Christopher M Rose, Javier J Pineda, Al Charest

Nat Commun· August 2018

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Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma.
Shuang Zhou, Vicky A Appleman, Christopher M Rose, Hyun Jung Jun, Juechen Yang, Al Charest

Life Sci Alliance· June 2018

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Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity.
Franz Ricklefs, Marco Mineo, Arun K Rooj, Ichiro Nakano, Al Charest

Cancer Res· May 2016

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PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations.
Helen Y Zou, Qiuhua Li, Lars D Engstrom, Melissa West, Vicky Appleman, Al Charest

Proc Natl Acad Sci U S A· March 2015

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ROS1 signaling regulates epithelial differentiation in the epididymis.
Hyun Jung Jun, Jeremy Roy, Tegan B Smith, Levi B Wood, Keara Lane, Al Charest

Endocrinology· September 2014

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Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.
Jaime Acquaviva, Hyun Jung Jun, Julie Lessard, Rolando Ruiz, Haihao Zhu, Al Charest

Cancer Res· December 2011

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Genetic modeling of gliomas in mice: new tools to tackle old problems.
Dolores Hambardzumyan, Luis F Parada, Eric C Holland, Al Charest

Glia· August 2011

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Report from the fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop.
David H Gutmann, Charles D Stiles, Scott W Lowe, Gideon E Bollag, Frank B Furnari, A L Charest

Neuro Oncol· July 2011

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The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.
Haihao Zhu, Steve Woolfenden, Roderick T Bronson, Zahara M Jaffer, Sofia Barluenga, Al Charest

Mol Cancer Ther· September 2010

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A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis.
Steve Woolfenden, Haihao Zhu, Al Charest

Genesis· October 2009

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