Publications by authors named "Keara Lane"

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Temporal tuning of switch-like virulence expression resolves environmental uncertainty through phenotypic heterogeneity.
Madison Spratt, Keara Lane

bioRxiv· July 2025

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Navigating Environmental Transitions: the Role of Phenotypic Variation in Bacterial Responses.
Madison R Spratt, Keara Lane

mBio· December 2022

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A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens.
Takamasa Kudo, Keara Lane, Markus W Covert

Cell Syst· May 2022

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Simultaneous cross-evaluation of heterogeneous datasets via mechanistic simulation.
Derek N Macklin, Travis A Ahn-Horst, Heejo Choi, Nicholas A Ruggero, Javier Carrera, Keara Lane

Science· July 2020

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Mechanically resolved imaging of bacteria using expansion microscopy.
Youngbin Lim, Anthony L Shiver, Margarita Khariton, Keara M Lane, Katharine M Ng

PLoS Biol· October 2019

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Escalating Threat Levels of Bacterial Infection Can Be Discriminated by Distinct MAPK and NF-κB Signaling Dynamics in Single Host Cells.
Keara Lane, Marta Andres-Terre, Takamasa Kudo, Denise M Monack, Markus W Covert

Cell Syst· March 2019

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Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level.
Miriam V Gutschow, John C Mason, Keara M Lane, Inbal Maayan, Jacob J Hughey

Mol Biol Cell· January 2019

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Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation.
Keara Lane, David Van Valen, Mialy M DeFelice, Derek N Macklin, Takamasa Kudo

Cell Syst· April 2017

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Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments.
David A Van Valen, Takamasa Kudo, Keara M Lane, Derek N Macklin, Nicolas T Quach

PLoS Comput Biol· November 2016

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ROS1 signaling regulates epithelial differentiation in the epididymis.
Hyun Jung Jun, Jeremy Roy, Tegan B Smith, Levi B Wood, Keara Lane

Endocrinology· September 2014

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Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.
Matthew J Lazzara, Keara Lane, Richard Chan, Paul J Jasper, Michael B Yaffe

Cancer Res· May 2010

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Dicer1 functions as a haploinsufficient tumor suppressor.
Madhu S Kumar, Ryan E Pester, Cindy Y Chen, Keara Lane, Christine Chin

Genes Dev· December 2009

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Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas.
Hyun Jung Jun, Steve Woolfenden, Shanie Coven, Keara Lane, Roderick Bronson

Cancer Res· March 2009

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ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.
Al Charest, Erik W Wilker, Margaret E McLaughlin, Keara Lane, Ram Gowda

Cancer Res· August 2006

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Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21).
Alain Charest, Keara Lane, Kevin McMahon, Julie Park, Elizabeth Preisinger

Genes Chromosomes Cancer· May 2003

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Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma.
Alan Charest, Vicky Kheifets, Julie Park, Keara Lane, Kevin McMahon

Proc Natl Acad Sci U S A· February 2003

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