Publications by authors named "Alan Roach"

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National variation in the composition of rheumatology multidisciplinary teams: a cross-sectional study.
Mwidimi Ndosi, Rachel Ferguson, Michael R Backhouse, Lindsay Bearne, Phillip Ainsworth, Alan Roach

Rheumatol Int· September 2017

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Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects.
Clare E Buckley, Anita Marguerie, Alan G Roach, Paul Goldsmith, Angeleen Fleming

Neuropharmacology· September 2010

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Decreased BDNF levels are a major contributor to the embryonic phenotype of huntingtin knockdown zebrafish.
Heike Diekmann, Oleg Anichtchik, Angeleen Fleming, Marie Futter, Paul Goldsmith, Alan Roach

J Neurosci· February 2009

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Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery.
Stéphane Berghmans, Paul Butler, Paul Goldsmith, Gareth Waldron, Iain Gardner, Alan Roach

J Pharmacol Toxicol Methods· October 2008

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Loss of PINK1 function affects development and results in neurodegeneration in zebrafish.
Oleg Anichtchik, Heike Diekmann, Angeleen Fleming, Alan Roach, Paul Goldsmith

J Neurosci· August 2008

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Non-associative learning in larval zebrafish.
Jonathan D Best, Stéphane Berghmans, Julia J F G Hunt, Samantha C Clarke, Angeleen Fleming, Alan G Roach

Neuropsychopharmacology· April 2008

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Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants.
Stephane Berghmans, Julia Hunt, Alan Roach, Paul Goldsmith

Epilepsy Res· June 2007

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Quinazoline and benzimidazole MCH-1R antagonists.
Rosa Arienzo, Sue Cramp, Hazel J Dyke, Peter M Lockey, Dennis Norman, Alan G Roach

Bioorg Med Chem Lett· March 2007

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Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors.
Steve Price, Walter Bordogna, Richard J Bull, David E Clark, Peter H Crackett, Alan G Roach

Bioorg Med Chem Lett· January 2007

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Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors.
Steve Price, Walter Bordogna, Ruth Braganza, Richard J Bull, Hazel J Dyke, Alan G Roach

Bioorg Med Chem Lett· January 2007

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Structure-activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists.
Rosa Arienzo, David E Clark, Sue Cramp, Stephen Daly, Hazel J Dyke, Alan G Roach

Bioorg Med Chem Lett· August 2004

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A virtual screening approach to finding novel and potent antagonists at the melanin-concentrating hormone 1 receptor.
David E Clark, Christopher Higgs, Stephen P Wren, Hazel J Dyke, Melanie Wong, Alan G Roach

J Med Chem· July 2004

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