Publications by authors named "Alessandra Polara"

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RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta-site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain.
Michael Honer, Alessandra Polara, Hiroto Kuwabara, Helmut Jacobsen, Axel Pähler

J Labelled Comp Radiopharm· July 2023

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β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.
Hans Hilpert, Wolfgang Guba, Thomas J Woltering, Wolfgang Wostl, Emmanuel Pinard, Alessandra Polara

J Med Chem· May 2013

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Multiple chirality transfers in the enantioselective synthesis of 11-O-debenzoyltashironin. Chiroptical analysis of the key cascade.
Alessandra Polara, Silas P Cook, Samuel J Danishefsky

Tetrahedron Lett· October 2008

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A fascination with 1,2-diacetals.
Steven V Ley, Alessandra Polara

J Org Chem· August 2007

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The total synthesis of (+/-)-11-O-debenzoyltashironin.
Silas P Cook, Alessandra Polara, Samuel J Danishefsky

J Am Chem Soc· December 2006

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Targeting C-reactive protein for the treatment of cardiovascular disease.
Mark B Pepys, Gideon M Hirschfield, Glenys A Tennent, J Ruth Gallimore, Melvyn C Kahan, Alessandra Polara

Nature· April 2006

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Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides.
Steven V Ley, Darren J Dixon, Richard T Guy, Maria A Palomero, Alessandra Polara

Org Biomol Chem· December 2004

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