Publications by authors named "Alessandro Senes"

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Packing of apolar amino acids is not a strong stabilizing force in transmembrane helix dimerization.
Gilbert J Loiseau, Alessandro Senes

Biophys J· November 2025

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High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq.
Samantha M Anderson, Joshua Choi, Emma M Cushman, Megan Leander, Srivatsan Raman, Alessandro Senes

PNAS Nexus· October 2025

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High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq.
Samantha M Anderson, Joshua Choi, Emma M Cushman, Megan Leander, Srivatsan Raman, Alessandro Senes

bioRxiv· May 2025

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Thermodynamic analysis of the GAS transmembrane motif supports energetic model of dimerization.
Gladys Díaz Vázquez, Qiang Cui, Alessandro Senes

Biophys J· January 2023

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The coiled-coil domain of Escherichia coli FtsLB is a structurally detuned element critical for modulating its activation in bacterial cell division.
Samuel J Craven, Samson G F Condon, Gladys Díaz Vázquez, Qiang Cui, Alessandro Senes

J Biol Chem· January 2022

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Analysis of spliceosome dynamics by maximum likelihood fitting of dwell time distributions.
Harpreet Kaur, Fatemehsadat Jamalidinan, Samson G F Condon, Alessandro Senes, Aaron A Hoskins

Methods· January 2019

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The Cytokinin Oxidase/Dehydrogenase CKX1 Is a Membrane-Bound Protein Requiring Homooligomerization in the Endoplasmic Reticulum for Its Cellular Activity.
Michael C E Niemann, Henriette Weber, Tomáš Hluska, Georgeta Leonte, Samantha M Anderson, Alessandro Senes

Plant Physiol· March 2018

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The FtsLB subcomplex of the bacterial divisome is a tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions.
Samson G F Condon, Deena-Al Mahbuba, Claire R Armstrong, Gladys Diaz-Vazquez, Samuel J Craven, Alessandro Senes

J Biol Chem· February 2018

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Combination of Cα-H Hydrogen Bonds and van der Waals Packing Modulates the Stability of GxxxG-Mediated Dimers in Membranes.
Samantha M Anderson, Benjamin K Mueller, Evan J Lange, Alessandro Senes

J Am Chem Soc· November 2017

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Ptc7p Dephosphorylates Select Mitochondrial Proteins to Enhance Metabolic Function.
Xiao Guo, Natalie M Niemi, Paul D Hutchins, Samson G F Condon, Adam Jochem, Alessandro Senes

Cell Rep· January 2017

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Screening for transmembrane association in divisome proteins using TOXGREEN, a high-throughput variant of the TOXCAT assay.
Claire R Armstrong, Alessandro Senes

Biochim Biophys Acta· November 2016

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Toward high-resolution computational design of the structure and function of helical membrane proteins.
Patrick Barth, Alessandro Senes

Nat Struct Mol Biol· June 2016

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BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes.
Zhi Zhang, Sabareesh Subramaniam, Justin Kale, Chenyi Liao, Bo Huang, Alessandro Senes

EMBO J· January 2016

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Fluorophores, environments, and quantification techniques in the analysis of transmembrane helix interaction using FRET.
Ambalika S Khadria, Alessandro Senes

Biopolymers· July 2015

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Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.
Guolin Ma, Ming Wei, Lian He, Chongxu Liu, Bo Wu, Alessandro Senes

Nat Commun· July 2015

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Backbone dependency further improves side chain prediction efficiency in the Energy-based Conformer Library (bEBL).
Sabareesh Subramaniam, Alessandro Senes

Proteins· November 2014

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A Gly-zipper motif mediates homodimerization of the transmembrane domain of the mitochondrial kinase ADCK3.
Ambalika S Khadria, Benjamin K Mueller, Jonathan A Stefely, Chin Huat Tan, David J Pagliarini, Alessandro Senes

J Am Chem Soc· October 2014

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The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.
Katarzyna A Gromek, Fabian P Suchy, Hannah R Meddaugh, Russell L Wrobel, Loren M LaPointe, Alessandro Senes

J Biol Chem· July 2014

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A frequent, GxxxG-mediated, transmembrane association motif is optimized for the formation of interhelical Cα-H hydrogen bonds.
Benjamin K Mueller, Sabareesh Subramaniam, Alessandro Senes

Proc Natl Acad Sci U S A· March 2014

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Measurement of transmembrane peptide interactions in liposomes using Förster resonance energy transfer (FRET).
Ambalika Khadria, Alessandro Senes

Methods Mol Biol· February 2014

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The transmembrane domains of the bacterial cell division proteins FtsB and FtsL form a stable high-order oligomer.
Ambalika S Khadria, Alessandro Senes

Biochemistry· October 2013

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Structural organization of FtsB, a transmembrane protein of the bacterial divisome.
Loren M LaPointe, Keenan C Taylor, Sabareesh Subramaniam, Ambalika Khadria, Ivan Rayment, Alessandro Senes

Biochemistry· April 2013

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An energy-based conformer library for side chain optimization: improved prediction and adjustable sampling.
Sabareesh Subramaniam, Alessandro Senes

Proteins· August 2012

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Structural informatics, modeling, and design with an open-source Molecular Software Library (MSL).
Daniel W Kulp, Sabareesh Subramaniam, Jason E Donald, Brett T Hannigan, Benjamin K Mueller, Alessandro Senes

J Comput Chem· July 2012

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Oligomerization state of photosynthetic core complexes is correlated with the dimerization affinity of a transmembrane helix.
Jen Hsin, Loren M LaPointe, Alla Kazy, Christophe Chipot, Alessandro Senes

J Am Chem Soc· September 2011

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