Publications by authors named "Alessandro Zarpellon"

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Human PAR1 expressed on mouse platelets contributes to hemostasis and arterial occlusion.
Sachiko Kanaji, Alessandro Zarpellon, Roberto Aiolfi, Yosuke Morodomi, Jennifer Orje

bioRxiv· June 2025

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Platelet glycoprotein V spatio-temporally controls fibrin formation.
Sarah Beck, Patricia Öftering, Renhao Li, Katherina Hemmen, Magdolna Nagy, Alessandro Zarpellon

Nat Cardiovasc Res· April 2023

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Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection.
Yosuke Morodomi, Sachiko Kanaji, Brian M Sullivan, Alessandro Zarpellon, Jennifer N Orje

Proc Natl Acad Sci U S A· November 2022

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The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse.
Sachiko Kanaji, Yosuke Morodomi, Hartmut Weiler, Alessandro Zarpellon, Robert R Montgomery

Haematologica· September 2022

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Humanized GPIbα-von Willebrand factor interaction in the mouse.
Sachiko Kanaji, Jennifer N Orje, Taisuke Kanaji, Yuichi Kamikubo, Yosuke Morodomi, Alessandro Zarpellon

Blood Adv· October 2018

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PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
Amanda L Gavin, Deli Huang, Christoph Huber, Annica Mårtensson, Virginie Tardif, Alessandro Zarpellon

Nat Immunol· September 2018

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Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics.
Michael B A Oldstone, Brian C Ware, Lucy E Horton, Megan J Welch, Roberto Aiolfi, Alessandro Zarpellon

Proc Natl Acad Sci U S A· August 2018

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Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia.
Taisuke Kanaji, My-Nuong Vo, Sachiko Kanaji, Alessandro Zarpellon, Ryan Shapiro

Proc Natl Acad Sci U S A· August 2018

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Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4.
Zane S Kaplan, Alessandro Zarpellon, Imala Alwis, Yuping Yuan, James McFadyen

Nat Commun· July 2015

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Type I interferon is a therapeutic target for virus-induced lethal vascular damage.
Roberto Baccala, Megan J Welch, Rosana Gonzalez-Quintial, Kevin B Walsh, John R Teijaro, Alessandro Zarpellon

Proc Natl Acad Sci U S A· June 2014

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Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.
Lea Scheppke, Eric A Murphy, Alessandro Zarpellon, Jennifer J Hofmann, Alona Merkulova

Blood· March 2012

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The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.
Conglei Li, Siavash Piran, Pingguo Chen, Sean Lang, Alessandro Zarpellon

J Clin Invest· November 2011

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Regulation of serotonin transport in human platelets by tyrosine kinase Syk.
Martina Pavanetto, Alessandro Zarpellon, Christian Borgo, Arianna Donella-Deana, Renzo Deana

Cell Physiol Biochem· May 2011

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Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Alessandro Zarpellon, Reha Celikel, James R Roberts, Richard A McClintock, G Loredana Mendolicchio

Proc Natl Acad Sci U S A· May 2011

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Unravelling the mechanism and significance of thrombin binding to platelet glycoprotein Ib.
Zaverio M Ruggeri, Alessandro Zarpellon, James R Roberts, Richard A Mc Clintock, Hua Jing

Thromb Haemost· November 2010

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Serotonin (5-HT) transport in human platelets is modulated by Src-catalysed Tyr-phosphorylation of the plasma membrane transporter SERT.
Alessandro Zarpellon, Arianna Donella-Deana, Alessandra Folda, Loris Turetta, Martina Pavanetto

Cell Physiol Biochem· March 2008

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Inhibitory effect by new monocyclic 4-alkyliden-beta-lactam compounds on human platelet activation.
Martina Pavanetto, Alessandro Zarpellon, Daria Giacomini, Paola Galletti, Arianna Quintavalla

Platelets· August 2007

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