Publications by authors named "Alex Salyer"

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Identification of Human Toll-like Receptor 2-Agonistic Activity in Dihydropyridine-Quinolone Carboxamides.
Ziwei Hu, Janardhan Banothu, Mallesh Beesu, Collin J Gustafson, Michael J H Brush, Alex C D Salyer

ACS Med Chem Lett· January 2019

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Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue.
Euna Yoo, Alex C D Salyer, Michael J H Brush, Yupeng Li, Kathryn L Trautman

Bioconjug Chem· August 2018

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Transcriptomal signatures of vaccine adjuvants and accessory immunostimulation of sentinel cells by toll-like receptor 2/6 agonists.
Alex C D Salyer, Sunil A David

Hum Vaccin Immunother· July 2018

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Identification of High-Potency Human TLR8 and Dual TLR7/TLR8 Agonists in Pyrimidine-2,4-diamines.
Mallesh Beesu, Alex C D Salyer, Michael J H Brush, Kathryn L Trautman, Justin K Hill

J Med Chem· March 2017

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Human Toll-like Receptor (TLR) 8-Specific Agonistic Activity in Substituted Pyrimidine-2,4-diamines.
Mallesh Beesu, Alex C D Salyer, Kathryn L Trautman, Justin K Hill, Sunil A David

J Med Chem· September 2016

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Identification of Adjuvantic Activity of Amphotericin B in a Novel, Multiplexed, Poly-TLR/NLR High-Throughput Screen.
Alex C D Salyer, Giuseppe Caruso, Karishma K Khetani, Lauren M Fox, Subbalakshmi S Malladi

PLoS One· July 2016

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pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation.
Lutz Nuhn, Nane Vanparijs, Ans De Beuckelaer, Lien Lybaert, Glenn Verstraete, Alex C D Salyer

Proc Natl Acad Sci U S A· July 2016

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Identification of a Human Toll-Like Receptor (TLR) 8-Specific Agonist and a Functional Pan-TLR Inhibitor in 2-Aminoimidazoles.
Mallesh Beesu, Giuseppe Caruso, Alex C D Salyer, Nijunj M Shukla, Karishma K Khetani

J Med Chem· April 2016

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Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.
Mallesh Beesu, Giuseppe Caruso, Alex C D Salyer, Karishma K Khetani, Diptesh Sil

J Med Chem· October 2015

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Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds.
Euna Yoo, Deepak B Salunke, Diptesh Sil, Xiaoqiang Guo, Alex C D Salyer

J Med Chem· October 2014

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Synthesis and immunological evaluation of a MUC1 glycopeptide incorporated into l-rhamnose displaying liposomes.
Sourav Sarkar, Alex C D Salyer, Katherine A Wall, Steven J Sucheck

Bioconjug Chem· March 2013

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3'-Modified oligodeoxyribonucleotides for the study of 2-deoxyribose damage in DNA.
Buthina Al-Oudat, Alex Salyer, Kevin Trabbic, Amanda Bryant-Friedrich

Bioorg Med Chem Lett· February 2013

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