Publications by authors named "Alexander Oster"

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Circulating HIV-Specific Interleukin-21(+)CD4(+) T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions.
Bruce T Schultz, Jeffrey E Teigler, Franco Pissani, Alexander F Oster, Gregory Kranias

Immunity· January 2016

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Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia.
Susan Johnson, Michael Eller, Jeffrey E Teigler, Sebastien M Maloveste, Bruce T Schultz, Alexander F Oster

J Virol· August 2015

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Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.
Miriam Schieffer, Heiko K Jessen, Alexander F Oster, Franco Pissani, Damien Z Soghoian

J Virol· July 2014

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17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development.
Sandrine Marchais-Oberwinkler, Claudia Henn, Gabriele Möller, Tobias Klein, Matthias Negri, Alexander Oster

J Steroid Biochem Mol Biol· May 2011

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Bicyclic substituted hydroxyphenylmethanone type inhibitors of 17 β-hydroxysteroid dehydrogenase Type 1 (17 β-HSD1): the role of the bicyclic moiety.
Alexander Oster, Tobias Klein, Claudia Henn, Ruth Werth, Sandrine Marchais-Oberwinkler

ChemMedChem· March 2011

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Bicyclic substituted hydroxyphenylmethanones as novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) for the treatment of estrogen-dependent diseases.
Alexander Oster, Stefan Hinsberger, Ruth Werth, Sandrine Marchais-Oberwinkler, Martin Frotscher

J Med Chem· November 2010

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Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.
Alexander Oster, Tobias Klein, Ruth Werth, Patricia Kruchten, Emmanuel Bey

Bioorg Med Chem· May 2010

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New insights into the SAR and binding modes of bis(hydroxyphenyl)thiophenes and -benzenes: influence of additional substituents on 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitory activity and selectivity.
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Matthias Negri, Patricia Kruchten, Alexander Oster

J Med Chem· November 2009

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Selective inhibition of 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) reduces estrogen responsive cell growth of T47-D breast cancer cells.
Patricia Kruchten, Ruth Werth, Emmanuel Bey, Alexander Oster, Sandrine Marchais-Oberwinkler

J Steroid Biochem Mol Biol· April 2009

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The role of the heterocycle in bis(hydroxyphenyl)triazoles for inhibition of 17beta-Hydroxysteroid Dehydrogenase (17beta-HSD) type 1 and type 2.
Yaseen A Al-Soud, Emmanuel Bey, Alexander Oster, Sandrine Marchais-Oberwinkler, Ruth Werth

Mol Cell Endocrinol· March 2009

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Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1).
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Ruth Werth, Matthias Negri, Yaseen A Al-Soud, Alexander Oster

J Med Chem· November 2008

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Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases.
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Patricia Kruchten, Martin Frotscher, Ruth Werth, Alexander Oster

Bioorg Med Chem· June 2008

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