Publications by authors named "Alexandr Hrabalek"

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Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Galina Karabanovich, Jan Dušek, Karin Savková, Oto Pavliš, Ivona Pávková

J Med Chem· September 2019

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Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
Jaroslav Roh, Galina Karabanovich, Hana Vlčková, Alejandro Carazo, Jan Němeček

Bioorg Med Chem· October 2017

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Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents.
Jan Němeček, Pavel Sychra, Miloslav Macháček, Markéta Benková, Galina Karabanovich

Eur J Med Chem· April 2017

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S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
Galina Karabanovich, Jan Němeček, Lenka Valášková, Alejandro Carazo, Klára Konečná

Eur J Med Chem· January 2017

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Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Galina Karabanovich, Júlia Zemanová, Tomáš Smutný, Rita Székely, Michal Šarkan

J Med Chem· March 2016

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1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
Galina Karabanovich, Jaroslav Roh, Tomáš Smutný, Jan Němeček, Petr Vicherek

Eur J Med Chem· July 2014

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The role of the trans double bond in skin barrier sphingolipids: permeability and infrared spectroscopic study of model ceramide and dihydroceramide membranes.
Barbora Skolová, Kateřina Jandovská, Petra Pullmannová, Ondřej Tesař, Jaroslav Roh

Langmuir· May 2014

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Transdermal delivery and cutaneous targeting of antivirals using a penetration enhancer and lysolipid prodrugs.
Denisa Diblíková, Monika Kopečná, Barbora Školová, Marcela Krečmerová, Jaroslav Roh

Pharm Res· April 2014

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Ceramides in the skin lipid membranes: length matters.
Barbora Skolová, Barbora Janůšová, Jarmila Zbytovská, Gert Gooris, Joke Bouwstra

Langmuir· December 2013

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Amino acid derivatives as transdermal permeation enhancers.
Barbora Janůšová, Barbora Skolová, Katarína Tükörová, Lea Wojnarová, Tomáš Simůnek

J Control Release· January 2013

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Enhanced topical and transdermal delivery of antineoplastic and antiviral acyclic nucleoside phosphonate cPr-PMEDAP.
Kateřina Vávrová, Petra Kovaříková, Barbora Skolová, Martina Líbalová, Jaroslav Roh

Pharm Res· December 2011

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Ammonium carbamates as highly active transdermal permeation enhancers with a dual mechanism of action.
Michal Novotný, Jana Klimentová, Barbora Janůšová, Karel Palát, Alexandr Hrabálek

J Control Release· March 2011

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Effect of ceramide acyl chain length on skin permeability and thermotropic phase behavior of model stratum corneum lipid membranes.
Barbora Janůšová, Jarmila Zbytovská, Petr Lorenc, Helena Vavrysová, Karel Palát

Biochim Biophys Acta· March 2011

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Transkarbams as transdermal permeation enhancers: effects of ester position and ammonium carbamate formation.
Michal Novotný, Alexandr Hrabálek, Barbora Janůsová, Jakub Novotný, Katerina Vávrová

Bioorg Med Chem Lett· May 2010

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Synthesis of fluorescent C24-ceramide: evidence for acyl chain length dependent differences in penetration of exogenous NBD-ceramides into human skin.
Jakub Novotný, Katerina Pospechová, Alexandr Hrabálek, Robert Cáp, Katerina Vávrová

Bioorg Med Chem Lett· December 2009

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Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: effects of linking chain length, chirality and polyfluorination.
Jakub Novotný, Petra Kovaríková, Michal Novotný, Barbora Janůsová, Alexandr Hrabálek

Pharm Res· April 2009

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Dicarboxylic acid esters as transdermal permeation enhancers: effects of chain number and geometric isomers.
Michal Novotný, Alexandr Hrabálek, Barbora Janůsová, Jakub Novotný, Katerina Vávrová

Bioorg Med Chem Lett· January 2009

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Permeation enhancer dodecyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: influence of pH, ion-pairing and skin species.
Katerina Vávrová, Katerina Lorencová, Jakub Novotný, Antonín Holý, Alexandr Hrabálek

Eur J Pharm Biopharm· November 2008

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Transdermal and dermal delivery of adefovir: effects of pH and permeation enhancers.
Katerina Vávrová, Katerina Lorencová, Jana Klimentová, Jakub Novotný, Antoni N Holý

Eur J Pharm Biopharm· June 2008

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Transkarbams with terminal branching as transdermal permeation enhancers.
Jana Klimentová, Petr Kosák, Katerina Vávrová, Tomás Holas, Jakub Novotný

Bioorg Med Chem Lett· March 2008

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HPLC method for determination of in vitro delivery through and into porcine skin of adefovir (PMEA).
Katerina Vávrová, Katerina Lorencová, Jana Klimentová, Jakub Novotný, Alexandr Hrabálek

J Chromatogr B Analyt Technol Biomed Life Sci· June 2007

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Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of Transkarbam 12.
Tomás Holas, Katerina Vávrová, Martin Síma, Jana Klimentová, Alexandr Hrabálek

Bioorg Med Chem· December 2006

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Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids.
Jana Klimentová, Petr Kosák, Katerina Vávrová, Tomás Holas, Alexandr Hrabálek

Bioorg Med Chem· December 2006

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Preliminary pharmaceutico-analytical evaluation of transkarbam 12 using liquid chromatography.
Ivana Pasáková, Jaroslav Sochor, Jiri Klimes, Alexandr Hrabálek

J Sep Sci· July 2006

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Synthesis and enhancing effect of transkarbam 12 on the transdermal delivery of theophylline, clotrimazole, flobufen, and griseofulvin.
Alexandr Hrabálek, Pavel Dolezal, Katerina Vávrová, Jarmila Zbytovská, Tomás Holas

Pharm Res· May 2006

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